Navigation Links
Osteoarthritis medicine delivered on-demand
Date:11/6/2013

Scientists are reporting development of a squishy gel that when compressed like at a painful knee joint releases anti-inflammatory medicine. The new material could someday deliver medications when and where osteoarthritis patients need it most. Their study appears in the ACS journal Biomacromolecules.

Xinqiao Jia, Chandran R. Sabanayagam and colleagues note that in the past few decades, researchers have been developing a variety of "smart" hydrogels that can release medications over several days rather than in a single burst. Most of these gels release medicine all the time or in response to changes in temperature, light or other factors. Very few respond to physical pressure, which is what causes pain in the 27 million osteoarthritis patients in the U.S. Osteoarthritis is called the "wear-and-tear" type of arthritis. The cartilage between the bones becomes damaged and wears away, making everyday movements of the knees, hands, backs and hips severely painful. Jia and Sabanayagam set out to develop an on-demand, drug-delivery system for pain management and tissue repair in a way that makes more sense for osteoarthritis patients.

They created a special type of hydrogel that responds to compression such as the pressure between joints that occurs in everyday movement and loaded it with an anti-inflammatory drug called dexamethasone, which is sometimes used to treat arthritis. When they compressed the hydrogel in the laboratory, it boosted the release of the drug. The researchers are currently testing their smart pain medications in laboratory animals.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Worlds largest meeting dedicated to osteoporosis and osteoarthritis opens in Rome
2. Less than 1 month to start of European Congress on Osteoporosis & Osteoarthritis in Rome
3. Yale Study links common chemicals to osteoarthritis
4. European Congress on Osteoporosis and Osteoarthritis
5. Lack of vitamin D contributes to pain in black Americans with knee osteoarthritis
6. UIC study examines exercise and weight loss for older adults with osteoarthritis
7. Scientists discover an epigenetic cause of osteoarthritis
8. College of Veterinary Medicine researcher doubles down on deadly, infectious cat diseases
9. Ludwig scientist Richard D. Kolodner elected to the Institute of Medicine
10. Leader of smoking cessation and tobacco prevention efforts receives Institute of Medicines 2013 Lienhard Award
11. Institute of Medicine Elects 70 New Members, 10 Foreign Associates
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/13/2017)... SANTA MONICA, Calif. , April 13, 2017 /PRNewswire/ ... New York will feature emerging and ... Innovation Summits. Both Innovation Summits will run alongside the ... variety of speaker sessions, panels and demonstrations focused on ... east coast,s largest advanced design and manufacturing event will ...
(Date:4/11/2017)... , April 11, 2017 NXT-ID, ... security technology company, announces the appointment of independent Directors Mr. ... to its Board of Directors, furthering the company,s corporate ... ... NXT-ID, we look forward to their guidance and benefiting from ...
(Date:4/4/2017)...   EyeLock LLC , a leader of iris-based ... Patent and Trademark Office (USPTO) has issued U.S. Patent ... an iris image with a face image acquired in ... 45 th issued patent. "The ... the multi-modal biometric capabilities that have recently come to ...
Breaking Biology News(10 mins):
(Date:7/26/2017)... ... July 26, 2017 , ... Cambridge Semantics ... that its Anzo Smart Data Lake® (Anzo SDL) product won ‘Best Text ... (SIIA) CODiE Awards. , Cambridge Semantics’ Anzo SDL uses Knowledge Graphs based ...
(Date:7/26/2017)... ... July 25, 2017 , ... The leading Regenerative Veterinary ... stem cell therapy has been used on more than 13,000 animals. VetStem ... potentially fatal injuries to tendons and ligaments. , In 2003 VetStem signed a ...
(Date:7/26/2017)... ... 26, 2017 , ... NLP Logix today announced a collaboration ... by Mayo Clinic and the experience in developing and deploying artificial intelligence solutions ... Microsoft Azure platform and will focus on assisting physicians to more accurately and ...
(Date:7/25/2017)... , ... July 25, 2017 , ... Fiberstar, Inc ... and beverage industry, offers Citri-Fi® 125. This natural citrus fiber is used to improve ... extend real tomato in sauces, condiments and spreads. Today, more than ever, consumers connect ...
Breaking Biology Technology: