Navigation Links
Osteoarthritis medicine delivered on-demand
Date:11/6/2013

Scientists are reporting development of a squishy gel that when compressed like at a painful knee joint releases anti-inflammatory medicine. The new material could someday deliver medications when and where osteoarthritis patients need it most. Their study appears in the ACS journal Biomacromolecules.

Xinqiao Jia, Chandran R. Sabanayagam and colleagues note that in the past few decades, researchers have been developing a variety of "smart" hydrogels that can release medications over several days rather than in a single burst. Most of these gels release medicine all the time or in response to changes in temperature, light or other factors. Very few respond to physical pressure, which is what causes pain in the 27 million osteoarthritis patients in the U.S. Osteoarthritis is called the "wear-and-tear" type of arthritis. The cartilage between the bones becomes damaged and wears away, making everyday movements of the knees, hands, backs and hips severely painful. Jia and Sabanayagam set out to develop an on-demand, drug-delivery system for pain management and tissue repair in a way that makes more sense for osteoarthritis patients.

They created a special type of hydrogel that responds to compression such as the pressure between joints that occurs in everyday movement and loaded it with an anti-inflammatory drug called dexamethasone, which is sometimes used to treat arthritis. When they compressed the hydrogel in the laboratory, it boosted the release of the drug. The researchers are currently testing their smart pain medications in laboratory animals.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Worlds largest meeting dedicated to osteoporosis and osteoarthritis opens in Rome
2. Less than 1 month to start of European Congress on Osteoporosis & Osteoarthritis in Rome
3. Yale Study links common chemicals to osteoarthritis
4. European Congress on Osteoporosis and Osteoarthritis
5. Lack of vitamin D contributes to pain in black Americans with knee osteoarthritis
6. UIC study examines exercise and weight loss for older adults with osteoarthritis
7. Scientists discover an epigenetic cause of osteoarthritis
8. College of Veterinary Medicine researcher doubles down on deadly, infectious cat diseases
9. Ludwig scientist Richard D. Kolodner elected to the Institute of Medicine
10. Leader of smoking cessation and tobacco prevention efforts receives Institute of Medicines 2013 Lienhard Award
11. Institute of Medicine Elects 70 New Members, 10 Foreign Associates
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/31/2016)... Florida , March 31, 2016 ... ) ("LegacyXChange" or the "Company") LegacyXChange ... potential users of its soon to be launched online ... ( https://www.youtube.com/channel/UCyTLBzmZogV1y2D6bDkBX5g ) will also provide potential ... use of DNA technology to an industry that is ...
(Date:3/22/2016)... , PROVO and ... -- Newborn Screening Ontario (NSO), which operates the highest ... for molecular testing, and Tute Genomics and UNIConnect, leaders ... technology respectively, today announced the launch of a project ... sequencing (NGS) testing panel. NSO has ...
(Date:3/15/2016)... 15, 2016 Yissum Research Development Company ... company of the Hebrew University, announced today the formation ... technology of various human biological indicators. Neteera Technologies has ... from private investors. ... detection of electromagnetic emissions from sweat ducts, enables reliable ...
Breaking Biology News(10 mins):
(Date:4/27/2016)... India , April 27, 2016 ... market research report with specific focus on US, ... Japan , to the healthcare business ... research library. Complete report on the ... 11 companies and supported with 282 tables and ...
(Date:4/26/2016)... Mass. (PRWEB) , ... April 26, 2016 , ... ... has been selected as one of three finalists for the European Inventor Award ... EPO’s annual innovation prize will be announced at a ceremony in Lisbon on June ...
(Date:4/26/2016)... ... , ... This unique "Fertility Happy Hour" event will be held at The ... the lowdown on female fertility and the reproductive technologies that are empowering a new ... IVF - The Arizona Center, will give a short presentation and answer questions ...
(Date:4/26/2016)... , VIENNA and ... -- The prize recognizes the innovation ... revolutionary innovations that will benefit patients and laboratory ... ) , Norma Instruments ... trend setting products in the field of hematology, ...
Breaking Biology Technology: