Navigation Links
Osteoarthritis medicine delivered on-demand
Date:11/6/2013

Scientists are reporting development of a squishy gel that when compressed like at a painful knee joint releases anti-inflammatory medicine. The new material could someday deliver medications when and where osteoarthritis patients need it most. Their study appears in the ACS journal Biomacromolecules.

Xinqiao Jia, Chandran R. Sabanayagam and colleagues note that in the past few decades, researchers have been developing a variety of "smart" hydrogels that can release medications over several days rather than in a single burst. Most of these gels release medicine all the time or in response to changes in temperature, light or other factors. Very few respond to physical pressure, which is what causes pain in the 27 million osteoarthritis patients in the U.S. Osteoarthritis is called the "wear-and-tear" type of arthritis. The cartilage between the bones becomes damaged and wears away, making everyday movements of the knees, hands, backs and hips severely painful. Jia and Sabanayagam set out to develop an on-demand, drug-delivery system for pain management and tissue repair in a way that makes more sense for osteoarthritis patients.

They created a special type of hydrogel that responds to compression such as the pressure between joints that occurs in everyday movement and loaded it with an anti-inflammatory drug called dexamethasone, which is sometimes used to treat arthritis. When they compressed the hydrogel in the laboratory, it boosted the release of the drug. The researchers are currently testing their smart pain medications in laboratory animals.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Worlds largest meeting dedicated to osteoporosis and osteoarthritis opens in Rome
2. Less than 1 month to start of European Congress on Osteoporosis & Osteoarthritis in Rome
3. Yale Study links common chemicals to osteoarthritis
4. European Congress on Osteoporosis and Osteoarthritis
5. Lack of vitamin D contributes to pain in black Americans with knee osteoarthritis
6. UIC study examines exercise and weight loss for older adults with osteoarthritis
7. Scientists discover an epigenetic cause of osteoarthritis
8. College of Veterinary Medicine researcher doubles down on deadly, infectious cat diseases
9. Ludwig scientist Richard D. Kolodner elected to the Institute of Medicine
10. Leader of smoking cessation and tobacco prevention efforts receives Institute of Medicines 2013 Lienhard Award
11. Institute of Medicine Elects 70 New Members, 10 Foreign Associates
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/16/2017)... --  Bridge Patient Portal , an enterprise patient ... Systems , an electronic medical record solutions developer ... a partnership to build an interface between the ... products, including Centricity Practice Solution (CPS), Centricity Business ... integrations will allow healthcare delivery networks using GE ...
(Date:4/18/2017)... April 18, 2017  Socionext Inc., a global expert in SoC-based ... edge server, the M820, which features the company,s hybrid codec technology. ... by Tera Probe, Inc., will be showcased during the upcoming Medtec ... show at the Las Vegas Convention Center ... Click here ...
(Date:4/11/2017)... April 11, 2017 Crossmatch®, a globally-recognized ... solutions, today announced that it has been awarded ... Projects Activity (IARPA) to develop next-generation Presentation Attack ... "Innovation has been a driving force within ... will allow us to innovate and develop new ...
Breaking Biology News(10 mins):
(Date:5/24/2017)... Washington, and WASHINGTON, DC, USA (PRWEB) , ... May 23, 2017 ... ... driver of the economy as well as an enabler of life-saving medical and other ... for optics and photonics . They joined others in the scientific community today in ...
(Date:5/23/2017)... , ... May 23, 2017 , ... A recent survey ... most troublesome and difficult to control weed in 12 categories of broadleaf crops, fruits ... 200 weed scientists across the U.S. and Canada participated in the 2016 survey, the ...
(Date:5/23/2017)... , ... May 22, 2017 , ... ... Photonics 2017 in San Diego, California, this August will feature high-level speakers ... and autonomous vehicles. , SPIE Optics and Photonics, the largest multidisciplinary optical sciences ...
(Date:5/23/2017)... ... ... Bacterial biofilms, surface adherent communities of bacteria that are encased in a ... and catheter infections to gum disease and the rejection of medical implants. Though ... year, there is currently a paucity of means for preventing their formation or treating ...
Breaking Biology Technology: