Navigation Links
Oregon researchers say supplement cuts muscle loss in knee replacements
Date:10/25/2013

EUGENE, Ore. -- (Oct. 25, 2013) -- Twenty grams of essential amino acids taken twice daily for a week before and for two weeks after knee-replacement surgeries helped 16 patients, mean age 69, recover faster and with much less muscle atrophy than a control group ingesting a placebo.

The approach -- detailed in a paper now online ahead of print in the Nov. 13 issue of the Journal of Clinical Investigation -- could spell relief and speed recovery for a growing population of aging adults who face total knee-replacements because of loss of mobility and pain problems. An estimated 3.48 million Americans are projected to need the surgery, known as total knee arthroplasty (TKA), by 2030.

The findings are part of an ongoing collaboration led by Hans C. Dreyer, a professor of human physiology at the University of Oregon, with the Eugene-based Slocum Research & Education Foundation and the Oregon Research Institute.

Atrophy in the quadriceps, a group of four muscles on the front of the thigh, has been a long-running problem following knee-replacement surgeries, Dreyer said.

In the study, 12 members of a control group receiving 40 grams a day of a non-essential amino acid supplement, a placebo, averaged an 18.4 loss in quadriceps muscle mass in their operated leg six weeks after surgery; those getting the supplement of eight essential amino acids (EEA) averaged a 6.2 percent loss. Eighty percent of atrophy occurred in the first two weeks after surgery. Atrophy in non-operative legs was about 50 percent of that in the operative leg in both groups. Muscle mass changes were seen with magnetic resonance imaging done at two and six weeks after surgery.

"We've learned that the essential amino acids were able to mitigate the amount of muscle loss," Dreyer said. "The functional measures that we looked at -- getting up out of a chair, going up a flight of stairs and going back down the stairs -- were all back to baseline in the t
'/>"/>

Contact: Jim Barlow
jebarlow@uoregon.edu
541-346-3481
University of Oregon
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Oregon Biodiversity Information Center wins 2013 Natureserve Network Collaboration Award
2. Ken Bierly of the Oregon Watershed Enhancement Board to receive ESA Regional Policy Award
3. BUSM researchers identify molecule that could aid lung cancer detection, treatment
4. Researchers identify gene variant that raises risk for colorectal cancer from eating processed meat
5. Researchers show how plants tell the time
6. Berkeley Lab researchers get a detailed look at a DNA repair protein in action
7. Researchers capture images of open channel that moves proteins across cell membranes
8. UAlberta medical researchers discover potential new treatment for colitis
9. Older siblings cells can be passed from female dogs to their puppies in the womb, MU researchers find
10. Nitrogen fertilizer remains in soils and leaks towards groundwater for decades, researchers find
11. Researchers discover innate virus-killing power in mammals
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Oregon researchers say supplement cuts muscle loss in knee replacements
(Date:7/9/2014)... piece of the puzzle behind nature,s ability to ... help advance the development of artificial photosynthesis for ... by an international collaboration of scientists led by ... Lab) and the SLAC National Accelerator Laboratory. ... (LCLS), the world,s most powerful x-ray laser, the ...
(Date:7/9/2014)... of increasing concern about the prevalence of antibiotic-resistant ... promising new pathway to disabling disease: blocking bacteria,s ... scientists showed how bacterial siderophore, a small molecule, ... fan bacterial growth as well as how ... infection process. Their findings appear in a recent ...
(Date:7/9/2014)... penguins shows that the population is 3.79 million ... estimated. Adlie penguins have long been considered a ... effects of climate change and fishing in the ... researchers from Stony Brook University and University of ... regular monitoring of Adlie penguins across their entire ...
Breaking Biology News(10 mins):Postcards from the photosynthetic edge 2Postcards from the photosynthetic edge 3Bacteria hijack plentiful iron supply source to flourish 2New study finds that Adélie penguin population is on the rise 2New study finds that Adélie penguin population is on the rise 3
... researchers from Princeton University and the Drexel University College ... malaria breaks down an important amino acid in its ... By depleting this substance called arginine, the parasite may ... disease. The scientists believe that shedding light on ...
... and University of Malaya (UM) today announced the establishment ... This is the first Centre of its kind in ... communities in terms of their diet and disease, conducting ... environment and health, providing assistance for the national cancer ...
... of the oil in the ocean bubbles up naturally from ... was of no value. Likewise, NASA satellites collect thousands of ... of it gets passed over because no one thinks there ... black gold bubbling up from an otherwise undistinguished mass of ...
Cached Biology News:Malaria parasite zeroes in on molecule to enhance its survival, team finds 2Malaria parasite zeroes in on molecule to enhance its survival, team finds 3Queen's University Belfast improves Malaysian public health 2Scientists find black gold amidst overlooked data 2Scientists find black gold amidst overlooked data 3
(Date:1/15/2014)... TaiGen Biotechnology Company, Limited ("TaiGen") today announced that ... leading Russian pharmaceutical company, to develop and commercialize nemonoxacin ... , Turkey and other ... novel antibiotic for the treatment of bacterial infections including ...
(Date:1/14/2014)... Carahsoft and CDS Federal Services have ... at 2pm EST (11am PST), “Natural Language Processing: Converting ... how technology can turn raw, heterogeneous data into actionable ... The online webinar will last approximately one hour. , ...
(Date:1/14/2014)... 2014  3D Communications, a leading provider of strategic communications services to ... events in the United States and ... Cox , JD, is returning to the firm,s Washington, ... 3D after more than two years of service as Associate Commissioner ...
(Date:1/14/2014)... EquitiesIQ, a leading informational research provider, ... is an emerging biomedical company acquiring, developing, manufacturing, and ... , Free report download: http://equitiesiq.com/reports/alliqua/ , In ... team and Board, which launched the company’s new strategy ...
Breaking Biology Technology:TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2Former FDA Associate Commissioner Returns To 3D Communications 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3
... 2011 Cytokinetics, Incorporated (Nasdaq: CYTK) announced today the ... issue of the journal Science regarding the ... omecamtiv mecarbil, and the potential therapeutic role that this ... failure. This publication reveals, for the first time ...
... and ST. GALLEN, Switzerland, March 17, 2011 Genomic ... results from nine studies utilizing the Onco type ... 12th Annual St. Gallen International Breast Cancer Conference in ... data that demonstrated the knowledge of a patient,s Recurrence ...
... Inc., a consulting firm that specializes in maximizing sales ... as Executive Account Director. Weimer has gained recognition and ... develop and inspire his teams to attain personal excellence ... organization,s goals. Delta Point CEO and founder ...
Cached Biology Technology:Cytokinetics announces fundamental research in cardiac myosin activation in the journal Science 2Cytokinetics announces fundamental research in cardiac myosin activation in the journal Science 3Genomic Health Presents Multiple International Studies Demonstrating Worldwide Value of Oncotype DX® Breast Cancer Test 2Genomic Health Presents Multiple International Studies Demonstrating Worldwide Value of Oncotype DX® Breast Cancer Test 3Genomic Health Presents Multiple International Studies Demonstrating Worldwide Value of Oncotype DX® Breast Cancer Test 4Genomic Health Presents Multiple International Studies Demonstrating Worldwide Value of Oncotype DX® Breast Cancer Test 5Genomic Health Presents Multiple International Studies Demonstrating Worldwide Value of Oncotype DX® Breast Cancer Test 6Genomic Health Presents Multiple International Studies Demonstrating Worldwide Value of Oncotype DX® Breast Cancer Test 7Genomic Health Presents Multiple International Studies Demonstrating Worldwide Value of Oncotype DX® Breast Cancer Test 8Ed Weimer Joins Delta Point, Inc. as Executive Account Director 2
CircuLex Anti-Human S100P Polyclonal Antibody Research Focus: proliferation Storage: -20C Shipping Temperature: 4C...
Mouse monoclonal [7E10] to C Peptide ( Abpromise for all tested applications). entrezGeneID: 3630 SwissProtID: P01308...
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide...
... epitope specific for Nabeta2 is ... known proteins.,SPECIES REACTIVITIES: It ... human because the immunogen sequence ... Reactivity with other species has ...
Biology Products: