Navigation Links
Oregon researchers say supplement cuts muscle loss in knee replacements
Date:10/25/2013

EUGENE, Ore. -- (Oct. 25, 2013) -- Twenty grams of essential amino acids taken twice daily for a week before and for two weeks after knee-replacement surgeries helped 16 patients, mean age 69, recover faster and with much less muscle atrophy than a control group ingesting a placebo.

The approach -- detailed in a paper now online ahead of print in the Nov. 13 issue of the Journal of Clinical Investigation -- could spell relief and speed recovery for a growing population of aging adults who face total knee-replacements because of loss of mobility and pain problems. An estimated 3.48 million Americans are projected to need the surgery, known as total knee arthroplasty (TKA), by 2030.

The findings are part of an ongoing collaboration led by Hans C. Dreyer, a professor of human physiology at the University of Oregon, with the Eugene-based Slocum Research & Education Foundation and the Oregon Research Institute.

Atrophy in the quadriceps, a group of four muscles on the front of the thigh, has been a long-running problem following knee-replacement surgeries, Dreyer said.

In the study, 12 members of a control group receiving 40 grams a day of a non-essential amino acid supplement, a placebo, averaged an 18.4 loss in quadriceps muscle mass in their operated leg six weeks after surgery; those getting the supplement of eight essential amino acids (EEA) averaged a 6.2 percent loss. Eighty percent of atrophy occurred in the first two weeks after surgery. Atrophy in non-operative legs was about 50 percent of that in the operative leg in both groups. Muscle mass changes were seen with magnetic resonance imaging done at two and six weeks after surgery.

"We've learned that the essential amino acids were able to mitigate the amount of muscle loss," Dreyer said. "The functional measures that we looked at -- getting up out of a chair, going up a flight of stairs and going back down the stairs -- were all back to baseline in the t
'/>"/>

Contact: Jim Barlow
jebarlow@uoregon.edu
541-346-3481
University of Oregon
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Oregon Biodiversity Information Center wins 2013 Natureserve Network Collaboration Award
2. Ken Bierly of the Oregon Watershed Enhancement Board to receive ESA Regional Policy Award
3. BUSM researchers identify molecule that could aid lung cancer detection, treatment
4. Researchers identify gene variant that raises risk for colorectal cancer from eating processed meat
5. Researchers show how plants tell the time
6. Berkeley Lab researchers get a detailed look at a DNA repair protein in action
7. Researchers capture images of open channel that moves proteins across cell membranes
8. UAlberta medical researchers discover potential new treatment for colitis
9. Older siblings cells can be passed from female dogs to their puppies in the womb, MU researchers find
10. Nitrogen fertilizer remains in soils and leaks towards groundwater for decades, researchers find
11. Researchers discover innate virus-killing power in mammals
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Oregon researchers say supplement cuts muscle loss in knee replacements
(Date:6/17/2015)... , Deutschland und GERMANTOWN, Maryland ... Investigator ®   Produktlinie mit DNA-Tests ... QIAGEN N.V. (NASDAQ: QGEN ; Frankfurt Prime Standard: ... neue STR-Testkits der Produktlinie Investigator ... in den Markt eingeführt. Die neuen Kits zur Erstellung ...
(Date:6/17/2015)... , June 17, 2015  Synaptics Inc. ... interface solutions, today announced that Xiaomi, one of ... Synaptics ® ClearPad ® family of ... driver integrated circuits (DDICs) for its latest smartphones, ... leveraging ClearPad for full in-cell display solutions and ...
(Date:6/16/2015)... 16, 2015 /CNW Telbec/ - handyem Inc. and ... the incorporation of handyem,s HPC-150 portable flow cytometer ... Mo-POD™. This unprecedented model of mobile laboratory platform ... the Pennsylvania Convention Center, ... th to 18 th 2015.  By ...
Breaking Biology News(10 mins):QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 2QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 3QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 4QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 5QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 6Synaptics Touchscreen and Display Driver IC Solutions Power Xiaomi's Latest Flagship Smartphones 2Synaptics Touchscreen and Display Driver IC Solutions Power Xiaomi's Latest Flagship Smartphones 3handyem and FlowMetric Diagnostics announce their partnership in the development of Flow Cytometry- Based Solutions in diagnostic capabilities 2handyem and FlowMetric Diagnostics announce their partnership in the development of Flow Cytometry- Based Solutions in diagnostic capabilities 3
... the brain can come under attack in patients with multiple ... an MS-like disease, the brain,s response to a protein produced ... or cerebellum that comes under fire. The studyfrom researchers at ... Washington University in St. Louiswill be published online on October ...
... possible explanation for why people who eat more fruit and ... They have shown that a fragment released from pectin, found ... to inhibit galectin 3 (Gal3), a protein that plays a ... for the anticancer effects of foods are based on population ...
... journal (October 12th) reveals how scientists from the ... a novel nanomechanical approach to investigate the workings of ... used to combat increasingly resistant infections such as MRSA. ... Gabriel Aeppli, developed ultra-sensitive probes capable of providing new ...
Cached Biology News:Pectin power 2Nanotechnology boosts war on superbugs 2
(Date:7/6/2015)... a leading Regulatory Service provider, today announced that it has opened a ... Colombia . Navitas, expansion into Latin America ... , the third largest economy in Latin America ... http://photos.prnewswire.com/prnh/20150703/228239LOGO ... Navitas regulatory professionals in close to or the same time zone and ...
(Date:7/3/2015)... ... July 03, 2015 , ... ... Fortune 500 companies and professional service industries alike-- typically known for its consummate ... laugh, honor a good cause and break from their day jobs. , "Our ...
(Date:7/3/2015)... Forskere kan ansøge ... http://www.openinnovationinscience.at om efteruddannelsesprogrammet "Lab for Open ... Wien .  ... og videnskabsmænd foretaget af Ludwig Boltzmann Gesellschaft ... sundhedsvidenskaben manglen på incitamenter til at undersøge ...
(Date:7/2/2015)... , ... July 02, 2015 , ... Sleepless nights will ... individual’s quality of sleep, launched its Indiegogo campaign on June 23. Sound sleepers and ... command technology makes it effortless to use, while the integration of the Bluetooth speaker, ...
Breaking Biology Technology:Navitas Launches Latin American Regulatory Operations Hub in Bogota, Colombia 2Navitas Launches Latin American Regulatory Operations Hub in Bogota, Colombia 3The Alexander Group Declares Their Independence with a Bit of Levity 2Lancering af verdens første åbne innovationsprogram til uddannelse af forskere 2Lancering af verdens første åbne innovationsprogram til uddannelse af forskere 3Luzi Smart Lamp Recently Launched Indiegogo Campaign 2Luzi Smart Lamp Recently Launched Indiegogo Campaign 3
... , , ... MindWorks, Inc. (CMI) announced today the release of Sevocity 08. ... new Conceptual MindWorks customers. Sevocity 08 is pre-market, conditionally ... (CCHIT(R)) and meets the Commission,s ambulatory electronic health record (EHR) ...
... LAKE MARY, Fla., Aug. 28 Renewable fuels ... that on August 26, 2009, it received a letter from ... the Company,s stockholders equity as reported in the Company,s Quarterly ... 2009, the Company is no longer in compliance with the ...
... Aug. 27 Champions Biotechnology, Inc. (OTC Bulletin Board: CSBR), ... and tumor specific data to enhance the value of oncology ... ended April 30, 2009. Full details of the Company,s financial ... www.championsbiotechnology.com. , , For the fiscal year ...
Cached Biology Technology:Sevocity EHR 08 Released With ARRA (Stimulus) Commitment 2New Generation Biofuels Receives NASDAQ Notice of Noncompliance with Continued Listing Requirements 2Champions Biotechnology Reports Fiscal 2009 Full-Year Financial Results 2Champions Biotechnology Reports Fiscal 2009 Full-Year Financial Results 3Champions Biotechnology Reports Fiscal 2009 Full-Year Financial Results 4Champions Biotechnology Reports Fiscal 2009 Full-Year Financial Results 5
ExonBio Service provides one-stop recobinant protein shopping from cloning, expression and purification. Price including gene cloning....
... 75 x 25 mm; ... recommended for immunohistochemistry of paraffin-embedded sections, ... end, markings will not ... precleaned, ...
Donor feline serum and plasma...
8 different frozen tissues are mounted on positively charged glass slides...
Biology Products: