Navigation Links
Optimal vitamin D dosage for infants uncertain
Date:4/30/2013

In a comparison of the effect of different dosages of vitamin D supplementation in breastfed infants, no dosage raised and maintained plasma concentrations within a range recommended by some pediatric societies. However, all dosages raised and maintained plasma concentrations within a lower range recommended by the Institute of Medicine, according to a study in the May 1 issue of JAMA, a theme issue on child health.

Hope Weiler, R.D., Ph.D., of McGill University, Montreal, presented the findings of the study at a JAMA media briefing.

"Vitamin D is important during periods of rapid bone mineral accrual. Nursing infants are susceptible to vitamin D deficiency because vitamin D in breast milk is limited," according to background information in the article. "A supplement of 400 IU of vitamin D per day is thought to support plasma 25-hydroxyvitamin D (25[OH]D) concentrations between 40 and 50 nmol/L; some advocate 75 to 150 nmol/L for bone health. the lack of well-defined recommendations supports the need for dose-response studies."

Dr. Weiler and colleagues conducted a study to investigate the efficacy of different dosages of oral vitamin D in supporting 25(OH)D concentrations in infants. The randomized clinical trial, which included 132 one-month-old healthy, term, breastfed infants, was conducted between March 2007 and August 2010. Infants were followed up for 11 months ending August 2011 (74 percent completed the study). Participants were randomly assigned to receive oral cholecalciferol (vitamin D3) supplements of 400 IU/d (n=39), 800 IU/d (n=39), 1,200 IU/d (n=38), or 1,600 IU/d (n=16).

The researchers found that the percentage of infants achieving the primary outcome of 75 nmol/L of 25(OH)D differed at 3 months by group (for 400 IU/d, 55 percent; for 800 IU/d, 81 percent; for 1,200 IU/d, 92 percent; and for 1,600 IU/d, 100 percent). "This concentration was not sustained in 97.5 percent of infants at 12 months
'/>"/>

Contact: Hope Weiler
hope.weiler@mcgill.ca
The JAMA Network Journals
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UNC Charlotte researcher leads effort to forecast optimal energy investments
2. Vitamin E identified as potential weapon against obesity
3. Quit smoking? Vitamin E may give extra boost to heart health
4. Excess vitamin E intake not a health concern
5. Vitamin P as a potential approach for the treatment of damaged motor neurons
6. Vitamin D benefits breathing in tuberculosis patients
7. Living in a sunny climate does not improve vitamin D levels in hip fracture patients
8. Folate and vitamin B12 reduce disabling schizophrenia symptoms in some patients
9. Organic tomatoes accumulate more vitamin C, sugars than conventionally grown fruit
10. Vitamin C is beneficial against the common cold
11. African-American, Caucasian women should take identical vitamin D doses
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... production from shale rock has increased by more ... do not fully understand the industry,s effects on ... the journal Frontiers in Ecology and the ... vastly outpace scientific examination, a team of eight ... Princeton University, concluded that determining the environmental impact ...
(Date:7/31/2014)... A first-of-its-kind study of bigeye tuna movements in ... of the Large Pelagics Research Center at the University ... fish cover a wide geographical range with pronounced north-south ... they favor a high-use area off Cape Hatteras southwest ... used a new approach to study one of the ...
(Date:7/31/2014)... genes to the earliest common ancestor of butterflies ... an extensive "Tree of Lepidoptera" in the first ... , Among the study,s more surprising findings: Butterflies ... to large ones, which completely changes scientists, understanding ... that some insects once classified as moths are ...
Breaking Biology News(10 mins):'Fracking' in the dark: Biological fallout of shale-gas production still largely unknown 2'Fracking' in the dark: Biological fallout of shale-gas production still largely unknown 3Study of bigeye tuna in Northwest Atlantic uses new tracking methods 2Study of bigeye tuna in Northwest Atlantic uses new tracking methods 3UF study advances 'DNA revolution,' tells butterflies' evolutionary history 2UF study advances 'DNA revolution,' tells butterflies' evolutionary history 3
... Without aggressive action to reduce soot emissions, the time ... be significantly accelerated in order to achieve international climate ... December,s Copenhagen Accord, according to " Assessing the climatic ... online June 21 in the Proceedings of the National ...
... product is organic, it,s also environmentally friendly. ... organic pesticides can have a higher environmental impact ... require larger doses. Environmental sciences professor Rebecca ... effectiveness and environmental impact of organic pesticides to ...
... freshwater fishes has created a great home for parasites, according ... . The study provides a lens into the evolutionary world ... probably has the best studied freshwater fish parasites in the ... more species of flukes in a few fishes from the ...
Cached Biology News:Aggressive action to reduce soot emissions needed to meet climate change goals 2Aggressive action to reduce soot emissions needed to meet climate change goals 3Organic pesticides not always 'greener' choice, study finds 2Adaptation is (not) in the eye of the beholder 2
(Date:7/31/2014)... 31, 2014 Food and natural ... searching for food alternatives that offer variety, as ... food ingredient market has numerous players operating in ... Vital Force Technology (VFT). VFT is a ... energetic patterns, all tested to produce stable, effective ...
(Date:7/31/2014)... good reason people over 60 are not donor candidates ... weakens with time, making the elderly prone to life-threatening ... research team now has discovered a reason why. , ... inability of blood-forming cells to maintain blood production over ... defects that could be restored for rejuvenation therapies," said ...
(Date:7/31/2014)... BLOOMINGTON, Ind. -- Chemists at Indiana University Bloomington ... in bricks-and-mortar fashion, a development with potential value ... as field-effect transistors and photovoltaic cells. , Their ... 3D Crystalline Solids and 2D Self-Assembled Crystals," has ... a journal of the Royal Society of Chemistry. ...
(Date:7/31/2014)... Graphite Metallizing Corporation announces GRAPHALLOY® ... These bearings are uniquely suited to prevent loss of ... of the high temperatures . , Recently, a ... design engineers at Graphite Metallizing to overcome problems with ... manufacturing operation, pans containing blocks of powder mixture are ...
Breaking Biology Technology:Functional Ingredient Manufacturer – Vital Force Technology Infuses Raw Materials & Ingredients with Subtle Energy Formula 2Key to aging immune system is discovered 2Chemists demonstrate 'bricks-and-mortar' assembly of new molecular structures 2Chemists demonstrate 'bricks-and-mortar' assembly of new molecular structures 3Graphite Metallizing Announces Bearings for High Temperature Oven Applications 2Graphite Metallizing Announces Bearings for High Temperature Oven Applications 3
... a private,biotechnology company and leading developer of clean ... Singapore,Pte. Ltd. (CLS). CLS is the company,s first ... the company,s research and development operations in the,U.S. ... business in,both the innovator and generics markets. ...
... Inc. (Amex: PLX ), announced today the pricing ... common stock at a,public offering price of $5.00 per ... underwriters to purchase up to 1,500,000 additional shares of,common ... Bank is acting as sole book-running manager for this,offering. ...
... Inc. (Nasdaq: HGSI ) today announced that it ... for the quarter ended,September 30, 2007. These results are ... (Logo: http://www.newscom.com/cgi-bin/prnh/20010612/HGSLOGO ) The conference call will ... Thursday, November 1, 2007, at 11:00 am Eastern Time. ...
Cached Biology Technology:Codexis Opens Singapore Laboratory 2Protalix BioTherapeutics Announces Pricing of Public Offering of Common Stock 2Human Genome Sciences To Sponsor Conference Call To Discuss Third Quarter 2007 Financial Results 2
UGT1A7 (E-15)...
Chicken Aortic Smooth Muscle Cells (CAOSMC) (>500,000 cells)...
... Hot Start Taq ... activity before the onset ... nonspecific amplification and primer-dimer ... is raised, the antibody ...
... UV irradiation and antimicrobial stainless steel to ... Quickly inactivate DNA between experiments with ... with antimicrobial coated stainless steel ... built-in 30-minute timer UVP's Sterilizing ...
Biology Products: