Navigation Links
Optimal dose of vitamin E maximizes benefits, minimizes risk
Date:10/30/2008

Corvallis, Oregon October 29, 2008 -- Vitamin E has been heralded for its ability to reduce the risk of blood clots, heart attack, and sudden death. Yet in some people, vitamin E causes bleeding. Scientists have known for more than 50 years that excess vitamin E promotes bleeding by interfering with vitamin K, which is essential in blood clotting. However, they haven't been able to pinpoint how the two vitamins interact. Nutrition researcher Maret Traber of Oregon State University reviews studies of possible explanations of the interaction in an article published recently in Nutrition Reviews.

One of the most compelling studies of the benefits of vitamin E is the Women's Health Study, in which 40,000 healthy women, 45 and older, took 600 IU vitamin E supplements or a placebo every other day for 10 years. Women taking the supplements had 24 percent fewer deaths from heart disease. Vitamin E's protective effect appeared even stronger in women 65 and older. Those taking the vitamin experienced a 26 percent reduction in cardiovascular events and a 49 percent reduction in cardiovascular deaths.

"That's a significant benefit," Traber said. Yet, she added, "In some people high doses of vitamin E increase the tendency to bleed. Women enrolled in the study had an increase in nose bleeds."

To lessen the bleeding risk, the U.S.-based Food and Nutrition Board in 2000 set the upper tolerable limit for daily vitamin E intake at 1500 I.U.

Research Traber reviewed suggests that a shared metabolic pathway in the liver causes vitamins E and K to interact. Vitamin K in the liver appears to diminish as vitamin E increases.

"Several different explanations could account for the interaction between the two vitamins," Traber said. "We need more research to understand the delicate balance between vitamins E and K."


'/>"/>

Contact: Amy Molnar
journalnews@bos.blackwellpublishing.net
201-748-8844
Wiley-Blackwell
Source:Eurekalert

Page: 1

Related biology news :

1. Genetics determine optimal drug dose of common anticoagulant
2. Vitamin K does not stem BMD decline in postmenopausal women with osteopenia
3. Lack of vitamin D linked to Parkinsons disease
4. Vitamin D a key player in overall health of several body organs, says UC Riverside biochemist
5. Vitamin C supplements may reduce benefit from wide range of anti-cancer drugs
6. Dont forget the vitamin A when working with its carrier protein
7. Variant of vitamin D receptor gene linked to melanoma risk
8. Majority of osteoporosis patients not receiving calcium and vitamin D with treatment
9. Vitamin A pushes breast cancer to form blood vessel cells
10. Researchers identify cancer preventive properties in common vitamin supplement
11. Newborn vitamin A reduces infant mortality
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/17/2014)... This news release is available in German . ... need millions of sperms every day in order to reproduce? ... questions are the topic of the latest issue of the ... 16th, 2014). The evolutionary biologist Steven Ramm from Bielefeld University ... nature, it is not unusual for a female to copulate ...
(Date:10/16/2014)... war on the human body. Battles are won, ... pancreatic cancer, this stalemate—known as tumor dormancy—can last ... a phenomena that is poorly understood. , ... of Salvatore Torquato, a Professor of Chemistry at ... tumor dormancy and the switch to a malignant ...
(Date:10/16/2014)... challenged conventional thinking on how the bowel lining develops ... how bowel cancer starts. , The researchers produced evidence ... the ,crypts, that are a feature of the bowel ... bowel cancer development, a controversial finding as scientists are ... 3D imaging technologies, Dr Chin Wee Tan and Professor ...
Breaking Biology News(10 mins):Sperm wars 2Modeling tumor dormancy 2Cryptic clues drive new theory of bowel cancer development 2
... - Animals that choose to eat in the presence of a ... go into a defensive mode and pay a physical penalty for ... crop pest hornworm caterpillar, a study shows. While other animals ... hornworm caterpillars slow or stop eating but actually keep up their ...
... to participate in ELIXIR ( www.elixir-europe.org ), a major ... in Europe. With one of Europe,s larger economies now ... is well placed to continue its excellent progress. ... infrastructure for managing biological data to support research and ...
... the IRCM, led by geneticist Dr. Jacques Drouin, recently ... inflammation. This important breakthrough will be published in tomorrow,s ... . IRCM scientists study glucocorticoids, a class ... reduce inflammation. They are used in medicine to treat ...
Cached Biology News:Caterpillar gets more from its food when predator is on the prowl 2Italy pledges to be part of ELIXIR research infrastructure 2Controlling inflammatory and immune responses 2
(Date:10/18/2014)... The Asian Electronic Medical Record (EMR) market report defines and ... of revenue. The electronic medical record market in the Asian ... at a CAGR of 9.4% from 2013 to 2018. , ... (EMR) market, to get an idea of the in-depth analysis ... the market in the same region, and is supported by ...
(Date:10/18/2014)... October 18, 2014 According to a ... & Well Type - Global Trends & Forecasts up ... $31 billion in 2011. This value is expected to ... by 2017, with 10% CAGR during the same period. ... fracturing production market in terms of hydraulic horse power ...
(Date:10/18/2014)... (PRWEB) October 18, 2014 The ... Stress, Holter Monitor), by End-user (Hospitals, Home/Ambulatory, Research ... (Single, 3-6, 12) -Global Forecast to 2020” provides ... challenges, opportunities, current market trends, and strategies impacting ... estimates and forecasts of the revenue and share ...
(Date:10/17/2014)... the looking-glass to Wonderland, mirrors in the real world ... a new class of mirror that works like no ... Society,s (OSA) new high-impact journal Optica ... new type of mirror that forgoes a familiar shiny ... an unusual magnetic property of a non-metallic metamaterial. ...
Breaking Biology Technology:The Asian Electronic Medical Record (EMR) market is estimated to grow to $2,328.0 million by 2018 - New Report by MicroMarket Monitor 2The Asian Electronic Medical Record (EMR) market is estimated to grow to $2,328.0 million by 2018 - New Report by MicroMarket Monitor 3The Asian Electronic Medical Record (EMR) market is estimated to grow to $2,328.0 million by 2018 - New Report by MicroMarket Monitor 4The Asian Electronic Medical Record (EMR) market is estimated to grow to $2,328.0 million by 2018 - New Report by MicroMarket Monitor 5Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 2Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 3Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 4The Electrocardiograph (ECG) Market Is Expected to Reach $5,435 Million By 2020 - New Research Report by MarketsandMarkets 2The Electrocardiograph (ECG) Market Is Expected to Reach $5,435 Million By 2020 - New Research Report by MarketsandMarkets 3The Electrocardiograph (ECG) Market Is Expected to Reach $5,435 Million By 2020 - New Research Report by MarketsandMarkets 4The Electrocardiograph (ECG) Market Is Expected to Reach $5,435 Million By 2020 - New Research Report by MarketsandMarkets 5Magnetic mirrors enable new technologies by reflecting light in uncanny ways 2Magnetic mirrors enable new technologies by reflecting light in uncanny ways 3Magnetic mirrors enable new technologies by reflecting light in uncanny ways 4
... , EXTON, Pa., July 15 ... and Cancer Innovations, Inc. (CII), a privately held biotechnology company ... they have entered into an evaluation and option agreement in ... , , The ...
... , , MADISON, Wis., ... (CDI) today announced that it has exclusively in-licensed a US-issued patent portfolio ... cells (cardiomyocytes) in drug testing. , , ... and Indiana University-Purdue University Indianapolis (IUPUI), covers ...
... , PRINCETON, N.J., July 15 ... license agreement with Merck KGaA, Darmstadt, Germany, providing the global ... platform for the research, development and commercialization of their antibody ... , "We are extremely pleased about ...
Cached Biology Technology:Morphotek(R), Inc. and Cancer Innovations, Inc. Announce Evaluation and Option Agreement for Therapeutic Monoclonal Antibodies 2Morphotek(R), Inc. and Cancer Innovations, Inc. Announce Evaluation and Option Agreement for Therapeutic Monoclonal Antibodies 3Cellular Dynamics International In-Licenses Key Patent Portfolio for Using Stem Cell-Derived Cells in Drug Testing 2Cellular Dynamics International In-Licenses Key Patent Portfolio for Using Stem Cell-Derived Cells in Drug Testing 3BioWa Announces License of POTELLIGENT(R) Technology to Merck KGaA 2
... monoclonal antibody reactive against the complex IV assembly ... in growing cultured cells. SURF1 is an important ... thought to participate in the folding of subunit ... Mutations of SURF1, particularly ones that result in ...
... (Thr183/Tyr185) Antibody Kit Kit Includes: ... #9251, 200 ul SAPK/JNK (56G8) Rabbit ... Cell Extracts, Catalog #9253, (4 Western ... #7074, 100 ul Anti-biotin IgG, HRP-linked ...
100 g monoclonal antibody which can immunocapture ~10 g of Complex IV from heart mitochondria. Also included are 2 mg of bovine heart mitochondria for control immunocapture....
Anti-gp120/160(SIV/mac239) Immunogen: gp120(SIV/mac239) protein (Genebank accession #M33262)...
Biology Products: