Navigation Links
Operation makes dementia patients faster and smarter
Date:1/25/2011

Researchers from the University of Gothenburg and Sahlgrenska University Hospital are the first in the world to show that an operation can help patients with dementia caused by white matter changes and hydrocephalus.

Presented in the American Journal of Neurosurgery, the results are based on the world's first study to demonstrate the effects of a shunt operation using a placebo control. 14 patients were followed for an average of three and a half years after the operation, with half being given a non-functioning shunt in other words a sham operation and the other half a functioning shunt. This is the equivalent to the placebo given in drug trials to determine how much of the treatment's effect is down to the patient's and others' expectations.

"For obvious reasons, this is problematic in a surgical context and surgical placebo studies are highly unusual," says Magnus Tisell, docent at the Sahlgrenska Academy and consultant neurosurgeon at Sahlgrenska University Hospital. "However, if you can actually do this kind of study, the level of evidence is the highest possible class 1."

The researchers found that patients' mental functions and ability to walk improved tangibly after having a shunt inserted. Half were given an open shunt right from the start and showed immediate improvement, while the other half were initially given a closed shunt and improved only after three months when the shunt was opened.

"Shunt operations have long been used for hydrocephalus, but this study offers more scientifically conclusive results to support the effect of the treatment, and also shows that shunt operations can help far more patients than previously believed with their walking and memory," says Tisell.

Surgery is not generally used today for patients with hydrocephalus and white matter changes. But the researchers' findings pave the way for a brand new group of patients who could benefit from a shunt operation.

"We believe that far more patients than is currently the case could benefit from a shunt operation, which will require more resources," says Tisell. "We also need to find out more about which patients are good candidates for the operation and which shunt is best in each particular case."


'/>"/>

Contact: Magnus Tisell
magnus.tisell@vgregion.se
46-073-400-2029
University of Gothenburg
Source:Eurekalert

Related biology news :

1. Up to 20 million euros for Munich Catalysis research cooperation
2. Cooperation in diabetes research
3. John P. Holdren addresses climate change, stressing need for international cooperation
4. ARS, industry cooperation yields device to detect insects in stored wheat
5. Leading entomologist to give talk at UCR on communication and cooperation in ant societies
6. HFSP President Arima and Secretary General Winnacker awarded for fostering cooperation with China
7. Nanyang Technological University and UK partners heightens cooperation in water industry
8. Negligible impact on public safety from shark cage diving operations
9. Ovarian transplantation: New technique gives greatly improved results in this delicate operation
10. First riser-drilling research operations undertaken
11. Supply Chain Council Partners With APICS The Association for Operations Management
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/2/2017)... 2, 2017  EyeLock LLC, a market leader of ... paper " What You Should Know About Biometrics in ... user authenticity is a growing concern. In traditional schemes, ... However, traditional authentication schemes such as username/password suffer from ... authentication offers an elegant solution to the problem of ...
(Date:1/30/2017)...   Invitae Corporation (NYSE: NVTA ... today announced that it will report its fourth quarter ... on Monday, February 13, 2017, and Invitae,s management team ... p.m. Eastern / 1:45 p.m. Pacific. ... financial results, guidance, and recent developments and will spend ...
(Date:1/24/2017)... NEW YORK , Jan. 24, 2017 /PRNewswire/ ... market study of the laboratory use of nuclear ... of 363 experienced end-users and profiled current practices, ... three years, as well as growth and opportunities. ... NMR, Instrument suppliers, NMR instruments, needs and innovation ...
Breaking Biology News(10 mins):
(Date:2/22/2017)... Therapeutics, Inc. (NASDAQ: PETX), a pet therapeutics company focused on ... companion animals, will host a live conference call on Tuesday, ... results from the fourth quarter and full year ended December ... access the audio webcast or use the conference ... ...
(Date:2/22/2017)... ... February 22, 2017 , ... Park Systems , a leader in Atomic ... all SPIE attendees and Park customers on Feb. 27, 2017 from 12-2pm ... Jose Convention Center. The luncheon will feature a talk on Automated AFM for ...
(Date:2/22/2017)... 2017 Scientists propose in Nature ... in Gaucher and maybe other lysosomal storage diseases as ... than current therapies. An international research team ... which also included investigators from the University of Lübeck ... Feb. 22. The study was conducted in mouse models ...
(Date:2/22/2017)... ... February 22, 2017 , ... ProMIS ... precision treatments for neurodegenerative diseases, today announced it has issued a scientific white ... is one of a series of commentaries from ProMIS’s scientific team offering insight ...
Breaking Biology Technology: