Navigation Links
Ontario Genomics Institute invests in validation of a novel protein interaction technology at U of T
Date:11/1/2012

TORONTO, ON, Nov. 1, 2012 - Every process in a cell is affected by interactions between proteins. Understanding how proteins react in the human body and their relationship to diseases is essential to the development of new and better targeted therapies. The Ontario Genomics Institute (OGI) is providing $100,000 through its Pre-commercialization Business Development Fund (PBDF) to the University of Toronto (U of T)'s Mammalian Membrane Two-Hybrid (MaMTH) project, which seeks to develop and commercialize a process to better understand membrane proteins in mammalian cells.

Dr. Igor Stagljar and his research team at U of T have developed a technology to analyze protein-protein interactions of mammalian integral membrane proteins. Membrane proteins, which make up approximately one-third of all proteins in a cell, are responsible for a variety of processes, making them attractive therapeutic targets. However, they are difficult to study because of their chemical complexity. This translational research tool will allow researchers to study interactions between membrane proteins of interest and how they respond to various therapeutic compounds in the context of the human cell.

"This tool has the potential to improve drug development and expand the resources available to companies developing new therapeutics," said Dr. Mark Poznansky, President and CEO, Ontario Genomics Institute. "Investment in projects like Dr. Stagljar's demonstrate OGI's commitment to fostering a vibrant life sciences community in Ontario."

Proteomic technologies such as MaMTH are increasingly playing key roles in the fields of medicine, drug discovery and molecular diagnostics. This tool has garnered attention from industry, who plan to license the technology if the project is successful. OGI's funding is essential for the development and validation necessary to make this assay commercially viable.

"We are pleased to receive this funding from OGI, which comes
'/>"/>

Contact: Christine Beyaert
cbeyaert@ontariogenomics.ca
416-673-6597
Ontario Genomics Institute
Source:Eurekalert

Page: 1 2

Related biology news :

1. New genomics study shows ancestry could help solve disease riddles
2. Physiological Genomics journal announces a major restructuring
3. 2 pioneering plant genomics efforts given a funding boost by National Science Foundation
4. ShanghaiBio Corporation Partners with Ingenuity Systems to Address Challenges in Analysis and Interpretation of Genomics Data
5. Elsevier launches new open access journal: Applied and Translational Genomics
6. The genomics symposium to boost the further development of cancer research
7. ACRG and BGI report findings from genomics research on recurrent hepatitis B virus integration
8. In search for a vaccine, IU biologist receives $2.3 million to explore chlamydia genomics
9. BGI, University of Helsinki and Wuhan University sign a MOU concerning cooperation on genomics
10. SDSCs big data expertise aiding genomics research
11. Reducing radiation: Heart Institute model shows hope for new standards worldwide
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 13, 2015 Technology Showcase, Hall E -   EyeLock ... today announced it will showcase its EyeLock ID technology integrated ... Department of Energy,s Oak Ridge National Laboratory (ORNL) ... EyeLock,s iris identity authentication technology is being used to validate ...
(Date:1/22/2015)... Jan. 21, 2015  Analyst Report Issued by Small Cap IR. ... showed that planet-wide, transactions at merchants on the leading payment ... number of credit, debit, and prepaid cards reached 6.54 billion.  ... of fraudulent card usage in 2012, and credit and debit ...
(Date:12/24/2014)... NEW YORK , Dec. 23, 2014  Since its launch in ... of people to eliminate the pain of trying to remember ... their own biometrics fused to their smartphones. To assist people ... Labs , the company that created 1U and focuses on ...
Breaking Biology News(10 mins):EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 2EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 3$4.80 Near Term Price Target with "Buy" given by CapRock Research for NXT-ID, Inc. (NASDAQ: NXTD) issued by Small Cap IR 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3
... Imagine devices that capture electricity from the air much ... light a house or recharge an electric car. Imagine using ... before it forms. Strange as it may sound, scientists already ... to a report at the 240th National Meeting of the ...
... smoke during pregnancy run the risk of adversely affecting their ... from rebro University, Sweden, published in the Journal of ... that boys, abilities may be affected to a greater extent ... University. There is a link between nicotine and ...
... visit garden centers in spring they will most likely ... home gardens. Studies have shown that consumers favor plants ... are "vegetative"a preference that can present multiple challenges for ... of ready-to-flower ornamentals like bedding plants and perennials start ...
Cached Biology News:Electricity collected from the air could become the newest alternative energy source 2Smoking during pregnancy may harm the child's motor control and coordination 2Rotating high-pressure sodium lamps provide flowering plants for spring markets 2
(Date:1/22/2015)... 21, 2015 Cambridge Semantics, the leading provider ... announced that 2014 was a record-breaking year across the board ... the Anzo Smart Data Platform and our Smart Data solutions, ... from diverse data which led to record growth for the ...
(Date:1/22/2015)... 2015 Crystal Diagnostics (CDx) Xpress System, a ... received AOAC-PTM Certifications for the six non-O157 Shiga toxin-producing E. ... referred to as STEC or the “Big-6”) as well as ... (cfu) per 325 g of raw ground beef and raw ...
(Date:1/22/2015)... January 22, 2015 Dr. Greg Leyer of ... annual Scripps Natural Supplements Pre-Conference seminar on probiotics in San ... an annual continuing education conference for health care professionals. This ... the topic of probiotics in health. Dr. Leyer spoke about ...
(Date:1/22/2015)... NJ (PRWEB) January 22, 2015 ... technologies such as the Bioruptor® and complete solutions ... system for chromatin immunoprecipitation, alleviating the need for ... and controls needed for ChIP of histones or ...
Breaking Biology Technology:Cambridge Semantics Announces Record Results for 2014 2Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens 2Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2
... , JEFFERSON, N.C., Aug. 5 Next Safety, Inc. ... to work in a pandemic environment. Next Safety is releasing for ... bird flu influenza A subtype H5N1. , , ... never became contagious. The Next Safety respirators are now being sold ...
... , , SANTA MONICA, Calif., ... the umbilical cord blood stem cell preservation company ( ... of stem cells to families nationwide and internationally, said today it ... "The two notes signed in February and March of 2007 respectively, ...
... are striving to develop organic solar cells that can be ... widely used to generate electricity. But a major obstacle ... structure at the nanoscale (tinier than 2-millionths of an inch) ... goal is to develop cells made from low-cost plastics that ...
Cached Biology Technology:Next Safety Releases Advanced Respirator for Infectious Diseases 2Next Safety Releases Advanced Respirator for Infectious Diseases 3Cord Blood America Retires $2.53M Obligation 2Cord Blood America Retires $2.53M Obligation 3Plastics that convert light to electricity could have a big impact 2Plastics that convert light to electricity could have a big impact 3
Our original highly-purified, robust Taq Polymerase which delivers consistently high yields and minimal background...
A formulation of our Biolase DNA Polymerase which contains a Red Loading Dye...
... (ELISA) test kits are qualitative one-step kits ... of drugs and/or their metabolites in forensic ... use only. It is recommended that all ... method such as GC/MS. The simple ...
... pending) is a protein based inhibitor of ... the most common and troublesome RNases including ... SUPERaseIn can be used in any application ... is ideal for in vitro transcription and ...
Biology Products: