Navigation Links
Oncolytics Biotech, Inc. announces publication of research
Date:1/7/2008

CALGARY, AB, January 7, 2008 -- Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) (Oncolytics) reported today that a research group led by Dr. Richard Vile of the Mayo Clinic College of Medicine in Rochester, Minnesota, published the results of its work testing the antitumor efficacy and safety of various combinations of reovirus and cyclophosphamide in vivo. The paper, entitled Cyclophosphamide Facilitates Antitumor Efficacy against Subcutaneous Tumors following Intravenous Delivery of Reovirus appears online in the January 1, 2008 issue of Clinical Cancer Research.

This exciting Mayo Clinic work supported the initiation of our combination REOLYSIN and cyclophosphamide clinical trial, recently approved by the U.K. health authorities, said Dr. Matt Coffey, Chief Scientific Officer of Oncolytics.

The purpose of the research study was to investigate whether it was possible to use cyclophosphamide, an immune modulator, to enhance the delivery and replication of the reovirus when delivered intravenously. After testing various doses and dosing regimens of reovirus and cyclophosphamide in mice, a metronomic dosing regimen was developed that resulted in increased survival, high levels of reovirus recovered from regressing tumors, levels of neutralizing antibodies that were protective, and only very mild toxicities. The data support investigation in human clinical trials of the use of cyclophosphamide prior to systemic reovirus administration to modulate, but not ablate, the immune system.


'/>"/>

Contact: Cathy Ward
cathy.ward@oncolytics.ca
403-670-7377
Oncolytics Biotech Inc.
Source:Eurekalert

Page: 1

Related biology news :

1. Selexis Announces Advanced Approach to Maximize Power of Genetic Elements for Rapid Development of High Performance Cell Lines
2. LaserCard Corporation Announces Expansion of Middle East Project
3. BIO-key(R) Announces Contracts for New Criminal Justice Data Sharing Solution
4. Balzan Foundation announces 2007 winners
5. The American Society of Plant Biologists announces 2007 awards
6. ASPB announces Summer Undergraduate Research Fellowship 2007 recipients
7. NIST announces 56 new awards for innovative technology research and development
8. Titanium Group Announces Contract With Haitong Securities
9. Measurement Specialties, Inc. Announces Impact of German Business Tax Reform 2008 Resulting in Lower Combined German Tax Rate - Impacts 2Q08 Reported Financial Results
10. FIJI Water announces sustainable growth initiative with commitment to help mitigate climate change
11. HGS announces positive Phase 2 LymphoStat-B at ACR meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... July 11, 2014 Research and Markets ... Biometrics Technology Market - Industry Analysis Size Share Growth ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... has created a need for high level security in ... personnel authentication such as username and passwords, tokens etc. ...
(Date:7/11/2014)... Brazil- In the brains of all vertebrates, information ... an electric or chemical signal to be passed ... which are the most abundant type of synapse, ... is crucial for learning, memory, perception and cognition, ... critical for brain function. For instance, every ...
(Date:7/10/2014)... Colo. , June 27, 2014  The ... the National Institute of Standards and Technology (NIST) ... of its academic research and forensic science expert ... The Board is an element of the NIST,s ... members are among the first appointments made to ...
Breaking Biology News(10 mins):International Biometrics Technology Market - Industry Analysis Size Share Growth Trends and Forecast to 2019 2Blame it on the astrocytes 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 3
... Juvenile Diabetes Research Foundation, a leader in setting the ... will begin a diabetes research collaboration with Pfizer, Hadassah ... drugs to replicate and regenerate insulin-producing cells in people ... the direction of Professor Benjamin Glaser (Hadassah Medical) and ...
... Medical Center have identified a new growth factor that ... cells in culture and in laboratory animals. The discovery, ... help researchers overcome one of the most frustrating barriers ... are so few in number and so stubbornly resistant ...
... Spanish . , Feeding the amino acid tryptophan ... makes them less aggressive and easier to manage, according to ... The tryptophan-enhanced diet reduced aggression and overall behavioral activity ... is only acquired through diet, is the precursor for the ...
Cached Biology News:JDRF, Pfizer, Hadassah Medical and the Hebrew University announce collaboration 2Newly identified growth factor promotes stem cell growth, regeneration 2Tryptophan-enriched diet reduces pig aggression 2
(Date:7/12/2014)... 12, 2014 This report ... used in the life science industry. Continuous ... science reagents market towards remarkable growth. The ... providers of life science reagents. , Brows ... http://www.transparencymarketresearch.com/life-sciences-reagents-analytical-reagents.html . , The global life science ...
(Date:7/11/2014)... DUBLIN , July 11, 2014 ... "International Transfection Technology Market - Global Industry Analysis, ... report to their offering. ... to introduce nucleic acids (either DNA or RNA) into ... therapy, mutation of cancer cells and protein metabolism by ...
(Date:7/11/2014)... 2014 /CNW/ - Sunovion Pharmaceuticals Canada Inc. (Sunovion) today ... acetate) for use as a once-daily adjunctive therapy for ... who are not satisfactorily controlled with conventional therapy.  APTIOM ... under 18 years of age. Epilepsy ... according to Epilepsy Canada, it affects 0.6% of the ...
(Date:7/10/2014)... Faso (PRWEB) July 10, 2014 ... today have access to an additional family planning ... access to contraception at all levels of the ... lower-dose formulation of a widely used contraceptive—Pfizer’s Depo-Provera® ... , Burkina Faso is the first of four ...
Breaking Biology Technology:Transparency Market Research: Life Science Reagents Market- PCR Reagent Kits, Cell and Tissue Culture, Flow Cytometry, Electrophoresis and Chromatography 2Transparency Market Research: Life Science Reagents Market- PCR Reagent Kits, Cell and Tissue Culture, Flow Cytometry, Electrophoresis and Chromatography 3International Transfection Technology Market - Industry Analysis, Size, Share, Growth, Trends and Forecast to 2019 2Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 2Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 3Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 4Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 2Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 3Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 4Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 5Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 6
... TurboSonic,Technologies, Inc. (OTC Bulletin Board: TSTA), a global ... control technologies, today,announced that the company,s CEO, Edward Spink ... Show., The interview gives viewers an overview of ... release., To view the clip ...
... sinus irrigation device) describes his successful treatment protocol for ... cavities using a pulsating irrigation device. This treatment has ... of sinus infections, snoring and sleep apnea., http://abclocal.go.com/kabc/story?section=news/health&id=6231390 ... ...
... Department of Labor Conference, WEST PALM BEACH, ... Department of Labor,s Recognition of Excellence Award in,the ... Deputy Assistant Secretary of Labor for Employment and,Training, ... honors,workforce investment programs from around the country that ...
Cached Biology Technology:[video] Edward Spink, CEO of TurboSonic Technologies, Inc. Discusses Contract With Biofuel Producer in Exclusive Interview on WallSt.net's 3-Minute Press Show 2Prominent Physician Achieves Success Using Topical Sinus Medications via Pulsitile Irrigation 2Workforce Alliance Receives U.S. Labor Department's Excellence Award 2Workforce Alliance Receives U.S. Labor Department's Excellence Award 3
Anti Autotaxin /ENPP2 , - (Rabbit)...
...
... 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose Pale yellow solid. An ... a nitric oxide donor in pancreatic ... bacteria. Causes DNA alkylation and DNA ... Purity: ≥95% by HPLC. Soluble in ...
... a silica based spin filter membrane to isolate ... DNA band is cut from an agarose gel ... The gel slice is melted irreversibly in a ... bound to the silica spin filter membrane and ...
Biology Products: