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Omega-3 lowers inflammation in overweight older adults
Date:6/20/2012

et contains between 15 and 17 times more omega-6 than omega-3, a ratio that researchers suggest should be lowered to 4-to-1, or even 2-to-1, to improve overall health.

"Scientists tend to agree that the best way to gauge a person's omega-3 status is to see whether that ratio goes down," Belury said. "That's what we saw in this study, and it was achieved through supplementation. We wanted participants to maintain normal diets and simply add this modest amount of oil to their existing diet. We expected and we found that their blood plasma omega-3 fatty acids went up in a dose-responsive manner."

The Food and Drug Administration considers daily omega-3 supplementation of up to 3 grams to be "generally regarded as safe." The doses in this study were within those safety parameters, but the researchers did not extend their findings to make a general recommendation about omega-3 supplementation.

"Although omega-3 fatty acids cannot take the place of good health behaviors, people with established inflammatory diseases or conditions may benefit from their use," Kiecolt-Glaser said.

The researchers also sought to determine whether omega-3 fatty acids could reduce depression symptoms, but participants had relatively few symptoms to begin with so no significant reductions were seen. Depression is also associated with chronic inflammation, but research hasn't yet fully defined the mechanisms behind that relationship.


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Contact: Jan Kiecolt-Glaser
Janice.Kiecolt-Glaser@osumc.edu
614-293-3499
Ohio State University
Source:Eurekalert

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