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Older siblings' cells can be passed from female dogs to their puppies in the womb, MU researchers find
Date:10/23/2013

puppies. The researchers found cells with Y-chromosomes in the mother after these births, meaning the mother had male cells present in her female body. The researchers also found genetically similar male cells in the mother's female puppies from a later litter. Those puppies were newborn and had never been pregnant, strongly suggesting that they acquired the cells that were left behind by their older brothers while in the womb.

"These new findings are significant because they suggest that the movement, or trafficking, of fetal cells is quite extensive in dogs, as has been suggested in people," Bryan said. "This degree of cell trafficking can have an impact on health, disease, and therapy, including in transplantation. The identification of this phenomenon strongly suggests that companion dogs will help us more rapidly understand the real impact of microchimerism in human medicine."

Kumar, Hansen, Axiak-Bechtel, and Bryan plan on continuing their research to follow the lifespans of dogs with microchimerism to determine to what diseases those dogs may be susceptible.


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Contact: Nathan Hurst
hurstn@missouri.edu
573-882-6217
University of Missouri-Columbia
Source:Eurekalert

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