Navigation Links
Old stain in a new combination
Date:5/20/2009

etocytes and thus improve the control of malaria," states Professor Dr. Olaf Mller, Project Head in the Department of Tropical Medicine and Public Health of the Hygiene Institute at the University of Heidelberg.

Methylene blue prevents transmission to mosquitoes

The appropriate component for such an alternative is a proven agent the methylene blue stain which has been given to malaria patients since the end of the 19th century has proven to be safe, well tolerated, and effective in combination with various malaria medications.

In the current study in Burkina Faso with 160 malaria patients between the ages of six and ten the Heidelberg scientists tested the effect of combination therapies with artemisinins and methylene blue on gametocytes in the blood. One group of the children received the standard treatment, consisting of a combination of artesunate and amodiaquine. Two other groups received methylene blue combined with one of the two drugs respectively. The physicians checked the number of gametocytes in blood samples three, seven, and fourteen days after the start of therapy.

Combination therapy is twice as effective as standard therapy

It was shown that both combination therapies are twice as effective against gametocytes as the standard therapy these parasites had almost completely disappeared in the first few days. "Methylene blue not only inhibits the formation of the reproductive forms, but also destroys already existing cells," explains Professor Mller. "In this way, the profiles of methylene blue and artemisinins, which quickly and effectively eliminate the parasites in the red blood cells, complement each other." Since the study group from Heidelberg has used methylene blue in Western Africa for years, it has already been adequately clinically tested severe or frequent side effects did not occur. Especially important is that the combination makes it more difficult for resistance to artemisi
'/>"/>

Contact: Prof. Olaf Mueller
Olaf.mueller@urz.uni-heidelberg.de
49-062-215-65035
University Hospital Heidelberg
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Grasslands: The future of sustainable agriculture
2. Going bananas for sustainable research -- scientists create fuel from African crop waste
3. K-State biologist collaborating with researchers in Africa on grassland sustainability, biodiversity
4. Organizational Change Management for Sustainability: The Harvard Case Study
5. Biofuels can provide viable, sustainable solution to reducing petroleum dependence
6. Symposium at UH will address how to put sustainability into practice
7. Biggest ever public investment in bioenergy to help provide clean, green and sustainable fuels
8. TXOTX, coordinated international project to contribute to sustainability of the marine resources
9. Abundance of ladybugs in olive orchards is an indicator of health and sustainability
10. Next generation microscopy: No stain, big gain
11. New publishing partnership for Energy for Sustainable Development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2015)... 30, 2015 To bolster its efforts and commitment ... announced today the addition of two new team members. ... advisor and David Raviv will act as head ... Corp.,s commitment to providing the most secure solutions for the ... co-founded Layer 7 Technologies, a provider of security and management ...
(Date:6/30/2015)... 30, 2015 Genisphere announced ... to help further develop Genisphere,s therapeutics capabilities and portfolio. ... having spent much of the last 25 years in ... Bioscience, and Johnson & Johnson. Tom started his career ... Biotech Corporate Finance. He graduated from Dartmouth College with ...
(Date:6/29/2015)... Research and Markets( http://www.researchandmarkets.com/research/zj7h4f/latin_america ) has ... Sensors Market - Growth, Trends & Forecasts (2014-2020)" ... Biomedical Sensors market is estimated at $0.65 billion by ... 2014-2020 The near future will bring Biomedical ... each individual. These sensors can be set to trigger ...
Breaking Biology News(10 mins):HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 2HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 3Genisphere Appoints New CEO, Thomas Bliss 2Genisphere Appoints New CEO, Thomas Bliss 3Latin America Biomedical Sensors Market Report 2015-2020 2
... serve society in numerous waysby providing timber, habitat ... example. Management of these multiple resources is a ... May 2007, the agency co-sponsored a biennial workshop ... researchers designed to present and discuss new ideas ...
... as stocks have declined sharply across the North Atlantic. ... mysterious as its long migrations, a recent study by ... United Kingdom says shifts in ocean-atmosphere conditions may be ... Although many aspects of spawning and early ...
... that helped Houston avoid the title of Americas smoggiest city ... to an $8.8 million grant from the Texas Commission on ... and Research Center at the University of Houston intends to ... and a heavy-duty engine dynamometer, a machine that tests an ...
Cached Biology News:Changes in ocean conditions in Sargasso Sea potential cause for decline in eel fishery 2Changes in ocean conditions in Sargasso Sea potential cause for decline in eel fishery 3State, UH teaming up to reduce (ob)noxious air emissions 2
(Date:7/1/2015)... ... 2015 , ... It is now possible to separate two common disorders: post-traumatic ... tomography (SPECT) according to researchers from Amen Clinics, UCLA, Thomas Jefferson University, and ... is believed to be the largest brain imaging study ever, will be published on ...
(Date:7/1/2015)... N.C. and PARIS ... firm AgBiome, and Genective, key developer of biotech ... the discovery of new generations of insect control ... insect control to counter the realities of advancing ... Genective, aligning AgBiome,s unique insect control technology with ...
(Date:7/1/2015)... , July 1, 2015   Decision Resources ... cited advantages of Otezla are its oral administration, ... as reported by surveyed rheumatologists. Otezla was the ... the treatment of active psoriatic arthritis in ... standard of care includes conventional oral treatments including ...
(Date:7/1/2015)... ... ... The next-generation sequencing (NGS) clinical market is poised for huge growth as ... Research reveals in its new report that the market drivers of this vibrant industry ... for better diagnostics as part of a molecular diagnostics trend. , The global market ...
Breaking Biology Technology:Brain Scans Can Tell Post-Traumatic Stress Disorder and Traumatic Brain Injury Apart According to New Research by Amen Clinics 2Brain Scans Can Tell Post-Traumatic Stress Disorder and Traumatic Brain Injury Apart According to New Research by Amen Clinics 3Brain Scans Can Tell Post-Traumatic Stress Disorder and Traumatic Brain Injury Apart According to New Research by Amen Clinics 4AgBiome and Genective collaborate to create novel insect-resistant crops 2Surveyed Rheumatologists Report That Otezla's Oral Administration is its Single Greatest Advantage Over Currently Available Treatment Options 2Surveyed Rheumatologists Report That Otezla's Oral Administration is its Single Greatest Advantage Over Currently Available Treatment Options 3NGS-Based Diagnostics, the ‘Must-Have Platform’, Sends Market Segment CAGRs Soaring According to BCC Research 2NGS-Based Diagnostics, the ‘Must-Have Platform’, Sends Market Segment CAGRs Soaring According to BCC Research 3
... China, April 24 /Xinhua-PRNewswire-FirstCall/ -- China Sky One,Medical, ... (OTC Bulletin,Board: CSKI), a pharmaceutical company for external ... ("PRC"), today announced it,acquired Heilongjiang Haina Pharmaceutical Inc. ... laws of the PRC on April,18, 2008., ...
... announced today that Chairman and CEO Fred Hassan purchased,just ... 000 shares at,an average purchase price of $18.26 per ... intention to purchase these shares in,January, this investment in ... -- including ZETIA and VYTORIN --,and our late- stage ...
... 24 /PRNewswire/ - Aegera Therapeutics Inc. is very,pleased ... and,financial executives to its Board of Directors: Mr. ... Managers Limited, and Mr. Gary,Littlejohn, Managing Director of ... experience and networks will be,critical for Aegera as ...
Cached Biology Technology:China Sky One Medical, Inc. Acquires Heilongjiang Haina Pharmaceutical Inc. 2China Sky One Medical, Inc. Acquires Heilongjiang Haina Pharmaceutical Inc. 3Aegera Therapeutics welcomes two experienced executives to its board of directors 2
... The Beacon 2000 Fluorescence Polarization System ... research and assay development. Standard Beacon ... 2000 System uses a quartz-halogen lamp ... of 360-700 nm. It accommodates all ...
The bench-top stand comfortably holds up to 6 Finnpipette Digital single- and multichannel pipettes. The crossbars are made of a grippy material to keep the pipettes firmly in place. Individual shelf...
Preparation Note: Prepared essentially by method of Singer, T.P., J. Biol. Chem., 174, 11 (1948). Quality Clarifier: Contains lipase Unit Definition: One unit will hydrolyze 1.0 μmole of p-ni...
... (PPase-2A) is a serine/threonine phosphatase isolated from ... as the heterodimer of 60kDa (A) and ... to dephosphorylate the a-subunit of phosphorylase kinase. ... broad substrate specificity and may play a ...
Biology Products: