Navigation Links
Offering hope for tissue regeneration
Date:2/26/2010

Providence, RI Researchers at Rhode Island Hospital have discovered how cells communicate with each other during times of cellular injury. The findings shed new light on how the body repairs itself when organs become diseased, through small particles known as microvesicles, and offers hope for tissue regeneration. The paper is published in the March 2010 edition of the journal Experimental Hematology and is now available online in advance of publication.

Lead author Jason Aliotta, MD, a physician researcher in the pulmonary/critical care and hematology/oncology departments at Rhode Island Hospital, and his colleagues focused their work on the microvesicles. These particles are several times smaller than a normal cell and contain genetic information such as messenger ribonucleic acid (RNA), other species of RNA and protein. The paper shows a novel mechanism by which the cells communicate with each other through these microvesicles. During times of cellular injury or stress, or with certain diseases like cancer, infections and cardiovascular disease, these particles are shed and then taken up by other cells in the body. The genetic information and protein in the microvesicles helps to reprogram the accepting cell to behave more like the cell from which the particle was derived.

Aliotta is also an assistant professor of medicine at The Warren Alpert Medical School of Brown University and a physician with University Medicine Foundation, Inc. He says, "What we attempted to understand is how cells within the bone marrow are able to repair organs that are unrelated to those bone marrow cells, such as the lung. Our work suggests that when the lung is injured or diseased and cells within the lung are stressed or dying, they shed microvesicles. Those microvesicles are then consumed by cells within the bone marrow, including stem cells, which are present in small numbers within the circulatory system. Those bone marrow cells then turn into lung
'/>"/>

Contact: Nancy Jean
njean@lifespan.org
Lifespan
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Stantum Offering Demo, Evaluation & Development Board Based on Its Patented Resistive Multi-Touch Technology
2. Scientists discover molecular pathway for organ tissue regeneration and repair
3. UT-Battelle licenses tissue regeneration technologies to NellOne Therapeutics, Inc.
4. $3.75 million grant advances tissue engineering partnership
5. New pathway discovered that may prevent tissue damage resulting from inflammation
6. Supportive materials will help regenerate heart tissue
7. Bioreactor for bone tissue engineering wins professor venture fair
8. For young boys with cancer, testicular tissue banking may be option to preserve fertility
9. A major step in making better stem cells from adult tissue
10. National Institutes of Health award Clemson $9.3 million for tissue regeneration center
11. KINAXO launches KinAffinity services for efficient profiling of kinase inhibitors in cells or tissue
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... , Dec. 15, 2014 The Defense ... it easier to detect and prevent counterfeit microcircuits ... Today the agency started performing an in-house microcircuit ... validate the authenticity of purchased microcircuits while increasing ... quality control measures will be conducted at DLA,s ...
(Date:12/15/2014)... 2014 Research and Markets ( ... "Global Facial Recognition Market 2015-2019" report ... http://photos.prnewswire.com/prnh/20130307/600769 Facial recognition is a ... recognition system measures the overall facial feature of ... and the distance between eyes. Facial recognition is ...
(Date:12/10/2014)... , Dec. 8, 2014 You,ve been here ... account but can,t remember your password, site key or the ... was your first grade teacher? Today, ... the app that will finally put an end to ... 1U TM . 1U leverages a user,s smartphone ...
Breaking Biology News(10 mins):Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3
... spinal cord injury is receiving attention in the research ... department of biomedical engineering at NJIT, recently has published ... stimulators for individuals with spinal cord injuries. ... of support from a four-year, $1.4 million National Institutes ...
... Inc. (Nasdaq: AWRE ), a global provider ... of the Next-Generation Universal Automated Booking Station, or "Universal ... of Justice. Universal ABS is a biometric enrollment application ... modular, COTS software framework that is far more easily ...
... S.C., Oct. 17, 2011 Integrated Biometrics, a South ... announced today that they have launched a new FBI ... device has been tested by The MITRE Corporation and ... Certified Product List. Watson is the world,s first non-optical ...
Cached Biology News:NJIT researcher testing micro-electronic stimulators for spinal cord injuries 2Aware Develops Next-Generation Biometric Enrollment Application for Department of Justice 2Aware Develops Next-Generation Biometric Enrollment Application for Department of Justice 3Aware Develops Next-Generation Biometric Enrollment Application for Department of Justice 4The World's First Non Optical FBI Appendix F Certified Fingerprint Sensor 2
(Date:12/24/2014)... The report provides basic ... definition, classification, application and industry overview. This ... and product cost structure. Production is separated ... also covers upstream raw materials, equipment, downstream ... and proposals. In the end, the export ...
(Date:12/24/2014)... BEIJING , Dec. 23, 2014 ... or the "Company"), a leading fully integrated plasma-based ... today announced that its majority-owned subsidiary, Shandong Taibang ... Practices ("GMP") certification from the China Food and ... factor production facility. As previously disclosed in the ...
(Date:12/24/2014)... Fla. , Dec. 23, 2014  Rock Creek ... that it has filed a Clinical Trial Application (CTA) ... Healthcare products Regulatory Agency (MHRA) seeking regulatory approval to ... lead molecule, Anatabine Citrate. Contingent on the ... conduct a Phase I trial to assess the safety, ...
(Date:12/22/2014)... Dec. 22, 2014 /PRNewswire/ - RepliCel Life Sciences Inc. ... company focused on the development of autologous cell therapies, ... the University of Calgary in conjunction with co-authors from ... further validates the company,s ongoing clinical research using dermal ... pattern baldness. The paper entitled " Hair ...
Breaking Biology Technology:Worldwide Methyl Mercaptan Market 2015-2020 Forecasts on Development & Trends Now Available at ReportsnReports.com 2China Biologic Receives GMP Certification for New Coagulation Factor Facility 2China Biologic Receives GMP Certification for New Coagulation Factor Facility 3Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 2Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 3Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 2Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 3Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 4Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 5
... 2012  Ariosa Diagnostics, a molecular diagnostics company, today ... will be available in the United States and ... and Integrated Genetics, a member of LabCorp,s Specialty ... for detection of common fetal trisomies utilizing a ...
... and manipulating nanoparticles, researchers at the National Institute of ... useful life more than tenfold.* This new approach, which ... experimenters the trapping time they need to build nanoscale ... nanoparticles inside biological cells without damaging the cells with ...
... China, May 4, 2012 /PRNewswire-Asia-FirstCall/ -- China Pharma Holdings, Inc. ... manufactures, and markets specialty pharmaceutical products in China, today announced ... 2012 financial results before the market opens on Tuesday, May ... conference call at 8:30 am ET on May 15, 2012 ...
Cached Biology Technology:Ariosa Diagnostics Announces Nationwide Launch of the Harmony™ Prenatal Test Through LabCorp 2Light touch keeps a grip on delicate nanoparticles 2China Pharma Holdings, Inc. to Report First Quarter of Fiscal Year 2012 Financial Results on May 15, 2012 2
LECHNER AND LaVECK MEDIUMfor the clonal growth of normal human bronchial and other epithelial cells. Requires additives. With glutamine.Recommended storage condition:oC to 8oCIntended use(s):research...
...
... System Modules Highly ... directional cloning into advanced ... vectors For ... Cloning Systems, the modules ...
... antibody-based immunoaffinity matrices, such as Sepharose ... without compromising antigen-antibody reactivity, the need ... has precluded the application of these ... CHEMICON Re-Blot Plus Western Blot Mild ...
Biology Products: