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Of lice and men (and chimps): Study tracks pace of molecular evolution
Date:1/7/2014

CHAMPAIGN, Ill. A new study compares the relative rate of molecular evolution between humans and chimps with that of their lice. The researchers wanted to know whether evolution marches on at a steady pace in all creatures or if subtle changes in genes substitutions of individual letters of the genetic code occur more rapidly in some groups than in others.

A report of the study appears in the Proceedings of the Royal Society B.

The team chose its study subjects because humans, chimps and their lice share a common historical fate: When the ancestors of humans and chimps went their separate ways, evolutionarily speaking, so did their lice.

"Humans are chimps' closest relatives and chimps are humans' closest relatives and their lice are each others' closest relatives," said study leader Kevin Johnson, an ornithologist with the Illinois Natural History Survey at the University of Illinois. "Once the hosts were no longer in contact with each other, the parasites were not in contact with each other because they spend their entire life cycle on their hosts."

This fact, a mutual divergence that began at the same point in time (roughly 5 million to 6 million years ago) allowed Johnson and his colleagues to determine whether molecular evolution occurs faster in primates or in their parasites.

Previous studies had looked at the rate of molecular changes between parasites and their hosts, but most focused on single genes in the mitochondria, tiny energy-generating structures outside the nucleus of the cell that are easier to study. The new analysis is the first to look at the pace of molecular change across the genomes of different groups. It compared a total of 1,534 genes shared by the primates and their parasites. To do this, the team had to first assemble a rough sequence o
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Contact: Diana Yates
diya@illinois.edu
217-333-5802
University of Illinois at Urbana-Champaign
Source:Eurekalert  

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