Navigation Links
Obesity and the central nervous system -- the state of the art
Date:8/31/2007

The past decade has witnessed an explosion of information regarding the role of the central nervous system (CNS) in the development of obesity and the influence of peripheral, hormonal signals that regulate CNS function to regulate food intake and metabolism. A symposium held recently in Washington, DC, organized by The Journal of Physiology, focused on recent work in talks by leaders in the field.

The speakers discussed state-of-the-art data and models regarding the brain as an initiator of obesity and as a target organ of peripheral feedback signals that regulate feeding behaviour. Reports of the talks by Barry Levin, Mary Dallman, and Gregory Morton are published in the September 1 issue of The Journal of Physiology, and they provide intriguing insights into the physiological basis of obesity.

As examples, Dr. Levin suggested that the physiological processes which drive all of us to seek and ingest food and limit energy expenditure during periods of negative energy balance provide an irresistible drive to regain lost adipose stores in weight-reduced obese individuals. This provides a potential basis for the well-recognized difficulty of maintaining weight loss. Dr. Dallman reported that conditions of reduced food allowance and chronic stress excite central neural networks that may lead toward abdominal obesity. This provides a potential link between stress and obesity.

Finally, Dr. Morton discussed that during a reduction in energy stores or circulating nutrients, the brain initiates responses to restore and maintain energy and glucose homeostasis. In contrast, in times of nutrient abundance and excess energy storage, the brain promotes reduced food intake and increased energy expenditure. An impaired ability of the brain to respond to hormonal or nutrient-related signals would be predicted to favour weight gain and insulin resistance and may contribute to the development of obesity and type 2 diabetes.

Together, these exciting presentations suggested potentially useful avenues of future research, which will hopefully provide improved preventive and therapeutic insights.


'/>"/>
Contact: Melanie Thomson
melanie.thomson@oxon.blackwellpublishing.com
01-865-476-270
Blackwell Publishing Ltd.
Source:Eurekalert

Related biology news :

1. Canadian youth 4th highest in international obesity study
2. Major link in brain-obesity puzzle found
3. Weight control protein may yield antiobesity drugs
4. Contagious obesity? Identifying the human adenoviruses that may make us fat
5. Study by Einstein researchers could lead to a novel strategy for treating obesity
6. Major obesity gene is lost in the shuffle
7. Sleep deprivation doubles risks of obesity in both children and adults
8. Higher levels of obesity associated with greater health risks
9. Obesity levels in US are grossly underestimated
10. Dragonflys metabolic disease provides clues about human obesity
11. Magic Beans -- Anti-obesity soya could help prevent diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/15/2016)... , April 15, 2016 ... "Global Gait Biometrics Market 2016-2020,"  report to their ... ) , ,The global gait biometrics market ... 13.98% during the period 2016-2020. Gait ... which can be used to compute factors that ...
(Date:3/31/2016)... 2016  Genomics firm Nabsys has completed a financial ... Bready , M.D., who returned to the company in ... leadership team, including Chief Technology Officer, John Oliver ... Nurnberg and Vice President of Software and Informatics, ... Dr. Bready served as CEO of Nabsys from ...
(Date:3/22/2016)... , PROVO and ... Newborn Screening Ontario (NSO), which operates the highest sample ... molecular testing, and Tute Genomics and UNIConnect, leaders in ... respectively, today announced the launch of a project to ... (NGS) testing panel. NSO has been ...
Breaking Biology News(10 mins):
(Date:5/24/2016)... CA (PRWEB) , ... May 24, 2016 , ... Last ... planning for corporate executives and entrepreneurs, held The Future of San Diego Life Science ... the San Diego life science community attended the event with speakers Dr. Rich Heyman, ...
(Date:5/23/2016)... Oxitec CEO Hadyn Parry ... a.m. ET before the United States House Committee on Science, ... play in controlling the spread of the Aedes aegypti ...      (Logo: http://photos.prnewswire.com/prnh/20150630/227348 ) Oxitec ... gene. Trials in Brazil , ...
(Date:5/20/2016)... ... ... The leading Regenerative Veterinary Medicine Company, VetStem Biopharma ., is proud ... of their own patients with the VetStem Cell Therapy. Each of these veterinarians has ... patients. , The veterinarians are Dr Ross Rich former owner of Cave Creek ...
(Date:5/19/2016)... Columbia , May 19, 2016  AdvancedFlow ... Innovations Inc. (AGI), based out of ... Greenlane Biogas Ltd. to its existing portfolio of ... manufacturing agreement. AFS along with its sister companies ... is a vertically integrated industrial group that specializes ...
Breaking Biology Technology: