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Obesity and passive smoking reduce oxygen supply to unborn baby
Date:3/16/2010

Babies born to mothers with obesity and exposed to passive smoking are more likely to have health problems than others. This conclusion is based on evidence of elevated levels of nucleated red blood cells in the umbilical cord reported in the International Journal of Food Safety, Nutrition and Public Health.

Pediatrician Abd ElBaky of the National Research Centre, in Cairo, and colleagues there and at Cairo University, Egypt, have found that obesity and passive smoking are risk factors for elevated umbilical cord neonatal immature, or nucleated red blood cells (NRBCs). Raised levels of NRBCs are indicative of a degraded oxygen supply to the baby during the pregnancy.

The team compared NRBC count in umbilical blood in three groups. Group I neonates (29 infants) were born to obese mothers. Group II (21 babies) were born to mothers exposed to tobacco smoke during pregnancy and a control group III (15 members). The team found that NRBC count was higher in groups I and II compared to the control group III. They also found that maternal body mass index (BMI) and infant birth weight were significantly higher in group I.

The team explains that, obesity in young and women is on the increase and is a known risk factor for a range of health problems. Maternal obesity at conception affects gestational metabolic adjustments, the placenta, and fetal growth and development. They add that neural tube defects and other developmental anomalies are more common in infants born to obese women. Pre-eclampsia, a potentially life-threatening condition involving raised blood pressure, is also more common in obese pregnant women.

Critically, the team says, fetal development during the last half of pregnancy depends on maternal metabolic adjustments detected by placental hormones and the subsequent oxygen and nutrient supply. If these are compromised, through obesity issues or exposure to tobacco smoke, then serious problems can occur.


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Contact: Abd ElBaky
abeernour66@yahoo.com
Inderscience Publishers
Source:Eurekalert

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