Navigation Links
Obesity and lack of exercise could enhance the risk of pancreatic cancer
Date:8/15/2007

inked IGFBP-1 (insulin-like growth factor binding protein one) with increased risk of colorectal and endometrial cancer. Like its name suggests, IGFBP-1 is a molecule that binds with insulin-like growth factor (IGF), a hormone normally associated with growth and development. In the laboratory, IGF has been noted to increase the growth of pancreatic cancer cells. Since one role of IGFBP-1 is to sequester IGF,

Dr. Wolpin and his colleagues were interested as to whether people who developed pancreatic cancer had lower blood levels of the IGFBP-1 protein.

To study the relationship between IGFBP-1 and pancreatic cancer, Dr. Wolpin and his colleagues chose pancreatic cancer patients enrolled in one of the four cohort studies and with blood drawn four or more years before developing cancer. The blood levels of IGFBP-1 from these patients were compared to those taken from 429 cancer-free people also enrolled in one of the cohort studies. According to their findings, patients with low blood levels of IGFBP-1 were nearly twice as likely to develop pancreatic cancer.

We still have much to learn about the mechanisms by which obesity and sedentary lifestyle may contribute to the risk of pancreatic cancer, Dr. Wolpin said. While it is too early to discuss IGFBP-1 as a suitable blood marker for pancreatic cancer, it is never too early to address the lifestyle issues that may contribute to low levels of IGFBP-1 and to an elevated risk of this difficult disease.


'/>"/>
Contact: Greg Lester
lester@aacr.org
267-646-0554
American Association for Cancer Research
Source:Eurekalert

Page: 1 2

Related biology news :

1. Canadian youth 4th highest in international obesity study
2. Major link in brain-obesity puzzle found
3. Weight control protein may yield antiobesity drugs
4. Contagious obesity? Identifying the human adenoviruses that may make us fat
5. Study by Einstein researchers could lead to a novel strategy for treating obesity
6. Major obesity gene is lost in the shuffle
7. Sleep deprivation doubles risks of obesity in both children and adults
8. Higher levels of obesity associated with greater health risks
9. Obesity levels in US are grossly underestimated
10. Dragonflys metabolic disease provides clues about human obesity
11. Magic Beans -- Anti-obesity soya could help prevent diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/13/2014)... New research raises the prospect of more effective ... muscle occurring in about half of all cancer patients, ... Dana-Farber Cancer Institute. , Many strategies have been tried ... that patients can,t endure potentially life-saving treatments, but none ... July 13 advanced online edition of Nature , ...
(Date:7/11/2014)... Society shows that no-take zones in Belize can ... lobster, conch, and fish recover from overfishing, but ... The reporttitled "Review of the Benefits of No-Take ... no-take areas around the world. The report was ... in marine protected areas and fisheries management. The ...
(Date:7/11/2014)... at the Department of Energy,s Oak Ridge National ... by R&D Magazine in recognition of the year,s ... the tremendous value of our National Labs," said ... at the National Labs continues to help our ... scientific and technological innovations necessary to remain globally ...
Breaking Biology News(10 mins):Antibody halts cancer-related wasting condition 2Antibody halts cancer-related wasting condition 3Belize's lobster, conch, and fish populations rebuild in no-take zones 2ORNL wins eight R&D 100s 2ORNL wins eight R&D 100s 3ORNL wins eight R&D 100s 4
... and under-diagnosed genetic disease in humans just may be ... College of Georgia researchers report. They are pursuing a ... wet form of macular degeneration, the leading cause of blindness ... iron, known to wreak cumulative havoc on the body,s organs, ...
... the tenth anniversary of the completion of the first draft of ... to complete the Wellcome Trust today launches a project to ... This will be one of the largest genome sequencing programmes ever ... in 6,000 people in the UK. The UK10K project is ...
... in German . , Missour/Leipzig. In ... African bird species with a very distinctive courtship behaviour, ... of the same species positively affects brooding females, improving ... birds in the experiment were more fertile and had ...
Cached Biology News:Link between iron overload and macular degeneration under study 2Link between iron overload and macular degeneration under study 3Ten years on, Wellcome Trust launches study of 10,000 human genomes in UK 2Ten years on, Wellcome Trust launches study of 10,000 human genomes in UK 3Pleasing to the eye 2Pleasing to the eye 3
(Date:7/10/2014)... Terascala, the industry leader in ... a former vice president of product management for Flexera ... of marketing. Terascala’s software when combined with leading compute ... highest performance and most reliable solutions for processing big ... channel expansion and broaden its product portfolio. His leadership ...
(Date:7/10/2014)... (PRWEB) July 10, 2014 OMICS Group’s ... techniques during 18-20 August, 2014 at Double Tree by ... the recent developments in Analytical & Bioanalytical research methods ... , Speaking on this occasion, Dr. Srinubabu Gedela, MD ... Acta conference is a remarkable one in bringing a ...
(Date:7/10/2014)... POINT, Ind. , July 10, 2014 ... expanded its use of capnography for respiratory ... growing group of healthcare leaders in embracing ... measures how effectively patients are breathing and ... depression occurs. By measuring the amount of ...
(Date:7/10/2014)... Utah , July 10, 2014 /PRNewswire-iReach/ ... annotation and interpretation, today announced an agreement ... (NGS) analytics for Lineagen,s NextStep Dx ... of neurodevelopmental and neurological disorders, currently offers ... microarray (CMA) testing service used by healthcare ...
Breaking Biology Technology:Terascala Expands Executive Team 2Terascala Expands Executive Team 3A Critical Review of Analytical Techniques for Improved Living Standards 2A Critical Review of Analytical Techniques for Improved Living Standards 3A Critical Review of Analytical Techniques for Improved Living Standards 4Franciscan St. Anthony Health-Crown Point Underscores Patient Safety Commitment Through Expanded Use of Capnography 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 3Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 4
... Researchers in India have demonstrated that producing nanoscopic crystals of ... by the gut even if the drug is not soluble ... the medicinal drugs being developed by the pharmaceutical industry dissolve ... a major problem for administering such drugs as it means ...
... ANGELES, Oct. 6 Entertain and interact.  That,s ... . ( www.drfresh.com ), the creator of the ... company behind the successful revival of the ... http://photos.prnewswire.com/prnh/20101006/LA77977LOGO ) (Logo:   http://www.newscom.com/cgi-bin/prnh/20101006/LA77977LOGO ) ...
... Inc. Against the Company And Certain of Its Subsidiaries ... ... --> ... var s = ,; var first_result; // Results are keyed by longUrl, so we need to ...
Cached Biology Technology:Nano drugs 2A 'Fresh' Approach to Marketing: Dr. Fresh™, Inc. Goes Guerilla With Internet-Based Campaigns 2Angiotech Pharmaceuticals, Inc. Announces Commencement of Arbitration and Litigation Proceedings by QSR Holdings, Inc. Against the Company And Certain of Its Subsidiaries 2Angiotech Pharmaceuticals, Inc. Announces Commencement of Arbitration and Litigation Proceedings by QSR Holdings, Inc. Against the Company And Certain of Its Subsidiaries 3Angiotech Pharmaceuticals, Inc. Announces Commencement of Arbitration and Litigation Proceedings by QSR Holdings, Inc. Against the Company And Certain of Its Subsidiaries 4Angiotech Pharmaceuticals, Inc. Announces Commencement of Arbitration and Litigation Proceedings by QSR Holdings, Inc. Against the Company And Certain of Its Subsidiaries 5Angiotech Pharmaceuticals, Inc. Announces Commencement of Arbitration and Litigation Proceedings by QSR Holdings, Inc. Against the Company And Certain of Its Subsidiaries 6Angiotech Pharmaceuticals, Inc. Announces Commencement of Arbitration and Litigation Proceedings by QSR Holdings, Inc. Against the Company And Certain of Its Subsidiaries 7Angiotech Pharmaceuticals, Inc. Announces Commencement of Arbitration and Litigation Proceedings by QSR Holdings, Inc. Against the Company And Certain of Its Subsidiaries 8Angiotech Pharmaceuticals, Inc. Announces Commencement of Arbitration and Litigation Proceedings by QSR Holdings, Inc. Against the Company And Certain of Its Subsidiaries 9
... CTI Molecular Imaging's proprietary Focus™ detector ... and a large imaging volume that ... image multiple mice or large primateswithout ... dedicated small animal PET (Positron Emission ...
...
These 18x18 square No.1 Corning cover glasses are made from No. 0211 zinc titania glass and are 0.16 to 0.19mm thick....
...
Biology Products: