Navigation Links
Obese male mice father offspring with higher levels of body fat
Date:6/16/2013

SAN FRANCISCO (June 16, 2013)Male mice who were fed a high-fat diet and became obese were more likely to father offspring who also had higher levels of body fat, a new Ohio University study finds.

The effect was observed primarily in male offspring, despite their consumption of a low-fat diet, scientists reported today at the annual meeting of The Endocrine Society in San Francisco, Calif.

"We've identified a number of traits that may affect metabolism and behavior of offspring dependent on the pre-conception diet of the father," said Felicia Nowak, an associate professor of biomedical sciences in Ohio University's Heritage College of Osteopathic Medicine who is lead author on the study.

The researchers point to epigeneticsthe way genes are expressed, as opposed to mutations in DNA that are "hard-wired into the genes"as a possible cause of these inherited traits. Because gene expression is impacted by environmental and lifestyle factors, this finding suggests that individuals with obese fathers may be able to proactively address health concerns.

The effect of parents' diet and weight on children has been well-established in humans, Nowak explained, but scientists have been studying the issue in mice to learn more about the biological mechanisms behind the phenomenon. The Ohio University team studied the impact of the high-fat diet only with male mice parents, as most of the previous research had focused on female mice parents.

To conduct the study, the researchers fed male mice a high-fat diet for 13 weeks before mating. (The female mates were fed a matched low-fat diet.) Male and female offspring were fed a standard low-fat diet and studied at 20 days, six weeks and at six and 12 months.

Compared with offspring from control mice (who were fed the low-fat diet), the male offspring of paternal mice with diet-induced obesity had higher body weight at six weeks of age. They also were more obese at the six- and 12-month study markers.
'/>"/>

Contact: Andrea Gibson
gibsona@ohio.edu
740-597-2166
Ohio University
Source:Eurekalert

Page: 1 2

Related biology news :

1. New study compares diets for weight management in obese children
2. Researchers unravel genetic mechanism of fatty liver disease in obese children
3. Obese patients face higher radiation exposure from CT scans -- but new technology can help
4. Obese moms give birth to heart healthier kids following bariatric surgery
5. Obese dogs at risk of health condition experienced by humans
6. Eating fewer, larger meals may prove healthier for obese women
7. First paternity study of southern right whales finds local fathers most successful
8. Happy Fathers Day! Another reason why dads and hopeful dads should quit smoking now
9. The old primates club: Even male monkeys ride their fathers coattails to success
10. Penn Study shows resistance to cocaine addiction may be passed down from father to son
11. Common genetic disease linked to fathers age
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... led by researchers at the University of Warwick in ... just published in the Journal Early Human Development ... spent in hospital after birth and the use of ... in preterm children. , Mathematic abilities are crucial for ... in very preterm children. Earlier studies of children who ...
(Date:9/2/2014)... the battle between our immune systems and cholera bacteria, ... known as phages. In a new study, researchers from ... National Public Health Laboratory, and elsewhere, report that phages ... in order to survive. Importantly, the study published ... escape from phage predation occurs during human infection. , ...
(Date:9/2/2014)... author Sam Kean stops by Reactions this week to ... shark that, despite what "Shark Week" may lead you ... at http://youtu.be/KhFygIoW_MA . , Kean,s book, "The Disappearing ... the History of the World from the Periodic Table ... a 10-episode video series produced for the newly launched ...
Breaking Biology News(10 mins):Mechanical ventilation a key indicator for pre-term children's math problems 2War between bacteria and phages benefits humans 2War between bacteria and phages benefits humans 3
... New research from The University of Western Ontario leads ... the Arctic Circle during the Pleistocene Epoch (approx. 150,000 ... three years later than modern day African elephants due ... nursing pattern could have contributed to the prehistoric elephant,s ...
... 21, 2010 Reportlinker.com announces that a new market ... Indian Biometric Market http://www.reportlinker.com/p0351944/Indian-Biometric-Market.html ... fastest emerging technology in the Indian Securities & Identification ... many conventional methods of Identity & Security checks like, ...
... Miscanthus x giganteus is the forerunner in the ... researchers believe "putting all their eggs in one basket" could ... recently reported the first natural occurrence in several decades of ... M. x giganteus is the only variety available, ...
Cached Biology News:Being good moms couldn't save the woolly mammoth 2New Miscanthus hybrid discovery in Japan could open doors for biofuel industry 2New Miscanthus hybrid discovery in Japan could open doors for biofuel industry 3
(Date:9/2/2014)... Ore. -- Scientists, including University of Oregon chemist ... create scaffolds of self-assembling, synthetic proteins called peptoid ... , The accomplishment -- detailed this week in ... the Proceedings of the National Academy of ... alternative design of the two-dimensional peptoid nanosheets that ...
(Date:9/2/2014)... NEW YORK , September 2, 2014 ... Market Study on Membrane Technology in Pharmaceutical, Biopharma and ... Witness Highest Growth by 2019" the global membrane technology market for ... 7,029.9 million in 2014 and is expected to grow ... to reach an estimated value of USD 10,886.0 million ...
(Date:9/2/2014)... , Sept. 2, 2014  Technology Applications International ... that its wholly-owned subsidiary Renuell Int,l, Inc. has signed ... and Space Administration ("NASA") at the Johnson Space Center ... See photos: tapplic.com/houstonphotos/ ... are very pleased to announce our latest, exclusive agreement ...
(Date:9/2/2014)... (PRWEB) September 02, 2014 Opertech ... new highly efficient, cost effective approach to sensory ... No. 8,820,265 by the U.S. Patent and Trademark ... Opertech. , “Opertech’s taste evaluation technology ... first automated high throughput system for rapid characterization ...
Breaking Biology Technology:UO-Berkeley Lab unveil new nano-sized synthetic scaffolding technique 2Global Membrane Technology Market Will Reach $10,886.0 Million in 2019: Persistence Market Research 2Global Membrane Technology Market Will Reach $10,886.0 Million in 2019: Persistence Market Research 3Global Membrane Technology Market Will Reach $10,886.0 Million in 2019: Persistence Market Research 4Global Membrane Technology Market Will Reach $10,886.0 Million in 2019: Persistence Market Research 5Technology Applications International Corporation Subsidiary Enters Into Additional Exclusive Agreement with NASA at a Signing Ceremony at the Johnson Space Center In Houston, Texas 2Technology Applications International Corporation Subsidiary Enters Into Additional Exclusive Agreement with NASA at a Signing Ceremony at the Johnson Space Center In Houston, Texas 3Opertech Bio Receives U.S. Patent for High-Throughput Taste Evaluation Technology 2
... Therapeutics,Inc. (OTC Bulletin Board: ARNI), today announced that ... has changed from "LRRI.OB" to "ARNI.OB",effective July 17, ... Inc. is a clinical-stage biopharmaceutical company,that develops and ... Arno,s lead compound is AR-67, a novel, third-generation,camptothecin ...
... Supply Solutions(R),a focus area within SAFC(R), a ... today that the Company has launched a ... with their regulatory,requirement under the new European ... Authorization and restriction of Chemicals,(REACH) http://www.safcsupplysolutions.com/reach ...
... N.J., July 16 Johnson & Johnson Pharmaceutical,Research ... Food and Drug,Administration,s (FDA) Anti-Infective Drugs Advisory Committee ... for DORIBAX(TM) (doripenem for,injection) for the treatment of ... (VAP)., The committee voted that 500 mg ...
Cached Biology Technology:Arno Therapeutics Announces New Ticker Symbol 2SAFC Supply Solutions Launches REACH-Compliant Products and Support 2SAFC Supply Solutions Launches REACH-Compliant Products and Support 3FDA Advisory Committee Provides Opinion of DORIBAX(TM) for the Treatment of Hospital-Acquired Pneumonia 2FDA Advisory Committee Provides Opinion of DORIBAX(TM) for the Treatment of Hospital-Acquired Pneumonia 3FDA Advisory Committee Provides Opinion of DORIBAX(TM) for the Treatment of Hospital-Acquired Pneumonia 4
Anti-hamster Ig HRP detection kit...
The 50 ml Magnetic Separation Rack is designed to be used for small-scale separations using magnetic particles. ,Capacity: four 50 ml tubes. ,Magnets: Neodymium rare earth permanent magnets....
...
Highly efficient electroporation solution suitable for transfection of plasmid DNA, oligonucleotides and siRNA. Compatible with all common electroporators....
Biology Products: