Navigation Links
Obese children more susceptible to asthma from air pollution
Date:1/22/2014

Obese children exposed to high levels of air pollutants were nearly three times as likely to have asthma, compared with non-obese children and lower levels of pollution exposure, report researchers at Columbia University Medical Center (CUMC).

Rates of childhood obesity and asthma have both increased dramatically in the past 30 years. The percentage of American children who are obese has increased from 7% in 1980 to 20% in 2008. Childhood asthma is up from 4% in 1980 to 10% in 2009. Rates are higher among urban minority populations.

The researchers followed 311 children in predominantly Dominican and African-American neighborhoods of New York City. They monitored indoor air in each child's home for two weeks at age 5 or 6, to measure exposure to a family of air pollutants, polycyclic aromatic hydrocarbons (PAH). The child's height and weight were measured and respiratory questionnaires were administered. In all, 20% were found to have asthma and 20% were categorized as obese based on body mass index.

The researchers found that high PAH exposure was associated with asthma only among obese children. In particular, the association was with the alkylated forms of PAH, which are emitted by vehicles and by cigarette smoke, cooking, incense, burning candles, and various other indoor sources. A two- to three-fold increase in asthma risk was seen among obese children exposed to high levels of the PAH chemicals 1-methylphenanthrene and 9-methylphenanthrene. Exposure to PAH or obesity alone did not predict asthma.

"Our results suggest that obesity may magnify the effects of these air pollutants, putting children at greater risk for having asthma," says lead author Kyung Hwa Jung, PhD, associate research scientist in the Department of Medicine at Columbia University College of Physicians and Surgeons (P&S).

The mechanism behind the association is not well understood. One possible explanation is that sedentary lifestyle in obese children could result in more time spent indoors, thereby increasing exposure to indoor PAH. Another may have to do with more rapid breathing in those who are obese.

Better understanding of the risk factors opens the door to more targeted interventions. "These findings suggest that we may be able to bring down childhood asthma rates by curbing indoor, as well as outdoor, air pollution and by implementing age-appropriate diet and exercise programs," says senior author Rachel Miller, MD, Professor of Medicine (in Pediatrics) and Environmental Health Sciences, chief of Pediatric Allergy and Immunology at CUMC, and co-deputy director of the Columbia Center for Children's Environmental Health at Columbia's Mailman School of Public Health.

The study builds on earlier research findings that linked increased asthma risk with exposure to higher levels of air pollution. Drs. Jung and Miller previously had shown an association between repeated high prenatal and childhood PAH exposure and asthma. A number of studies also have found an association between obesity and asthma.


'/>"/>

Contact: Timothy S. Paul
tp2111@columbia.edu
212-305-2676
Columbia University's Mailman School of Public Health
Source:Eurekalert

Related biology news :

1. For obese teen girls, aerobic exercise may trump resistance training in health benefits
2. Obese stomachs tell us diets are doomed to fail
3. Obese dads pass on predisposition to obesity and metabolic disorders to their kids
4. Food contaminants worsen metabolic problems in obese mice
5. People with a disability more likely to be obese, have chronic illnesses
6. Obese male mice father offspring with higher levels of body fat
7. Eating fewer, larger meals may prove healthier for obese women
8. Obese dogs at risk of health condition experienced by humans
9. Obese moms give birth to heart healthier kids following bariatric surgery
10. Obese patients face higher radiation exposure from CT scans -- but new technology can help
11. Researchers unravel genetic mechanism of fatty liver disease in obese children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/15/2016)... , April 15, 2016  A new ... make more accurate underwriting decisions in a fraction ... timely, competitively priced and high-value life insurance policies ... screenings. With Force Diagnostics, rapid testing ... lifestyle data readings (blood pressure, weight, pulse, BMI, ...
(Date:4/14/2016)... 2016 BioCatch ™, the ... announced the appointment of Eyal Goldwerger as ... Goldwerger,s leadership appointment comes at a time of ... deployment of its platform at several of the world,s ... discerns unique cognitive and physiological factors, is a winner ...
(Date:3/31/2016)... March 31, 2016   ... or the "Company") LegacyXChange is excited to ... its soon to be launched online site for trading ... ) will also provide potential shareholders a sense ... technology to an industry that is notorious for fraud. ...
Breaking Biology News(10 mins):
(Date:4/29/2016)... ... April 29, 2016 , ... Intelligent Implant Systems announced ... FDA via 510(k) for sale in the United States. These components expand the ... fusions. With one-level sales beginning in October of 2015, the company has seen ...
(Date:4/28/2016)... NEW YORK , April 28, 2016 /PRNewswire/ ... biotechnology acceleration company reports the Company,s CEO  was ... capital titled Accelerators Enter When VCs Fear To ... Life Science Leader magazine is an ... work for everything from emerging biotechs to Big ...
(Date:4/28/2016)... New York, NY (PRWEB) , ... April 28, ... ... plan, QuickSTAT has made significant investments in recruiting top industry experts, and expanding ... IT Platform, which provides industry-leading tools for clients to manage their clinical trial ...
(Date:4/27/2016)... ... April 27, 2016 , ... Shimadzu ... at the Spring 2016 Marijuana Business Conference and Expo. Shimadzu’s high-performance instruments enable ... metals, and more. Expo attendees can stop by booth 1021 to learn how ...
Breaking Biology Technology: