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OU study suggests the bacterial ecology that lives on humans has changed in the last 100 years
Date:12/13/2012

ment can be made that remote traditional communities are not truly removed from modern human ecologies. They may receive milk or other food sources from the government, which could alter the microbial ecology of the community. Our evolutionary cousins, non-human primates are important to consider. However, the human-chimp common ancestor was over six million years ago, which is a lot of time for microbiomes to evolve distinct, human signatures."

Retrieving ancient human microbiome data is complementary to these studies. However, studying ancient microbiomes is not without problems. Assuming DNA preserves, there is also a problem with contamination and modification of ancient samples, both from the soil deposition, and from other sources, including the laboratory itself.

"In addition to laboratory controls in our study, we use an exciting new quantitative approach called source tracking developed by Dan Knights from Rob Knight's Laboratory at the University of Colorado in Boulder, which can estimate how much of the ancient microbiome data is consistent with the human gut, rather than other sources, such as soil," explains Lewis.

"We discovered that certain samples have excellent gut microbiome signatures, opening the door for deeper analyses of the ancient human gut, including a better understanding of the ancient humans themselves, such as learning more about their disease burdens, but also learning more about what has changed in our gut today."


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Contact: Jana Smith
jana.smith@ou.edu
405-325-1322
University of Oklahoma
Source:Eurekalert

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