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OSU study shows exposure to bad air raises blood pressure
Date:7/28/2008

one week.

The air pollution level inside the chamber containing particulate matter was comparable to levels a commuter may be exposed to in urban areas with heavy traffic such as downtown Manhattan. "Pre-exposure to air pollution markedly increased blood pressure responses following infusion of angiotensin II," added Rajagopalan.

According to the U.S. Environmental Protection Agency (EPA), the four most common pollutants emitted into the air are particulate matter, ozone, nitrogen dioxide and sulfur dioxide. Air pollution is commonly the result of industrial emissions, coal burning, power plants and automobile exhaust.

"This study provides guidance for the EPA to change pre-existing stringent standards in the effort to reduce air pollution," says Rajagopalan. "Our study also confirmed a need for a broader based approach, from the entire world, to influence policy development."

Qinghua Sun, first author of the study, will analyze vascular function in humans before and after the upcoming summer Olympics in Beijing, China. With stringent laws to ensure good quality during the games, it is anticipated that the air quality will improve significantly in and around Beijing. "We expect to find a tangible impact on vascular function and blood pressure because ultimately the only thing that will have changed is levels of air pollution," says Sun.

Researchers at the University of Michigan, the U.S. Environmental Protection Agency, the Institute of Statistical Science and the New York University School of Medicine participated in the study.

Along with Rajagopalan and Sun, other Ohio State researchers involved in the study were Peibin Yue, Zhekang Ying and Arturo J. Cardounel. Funding from the National Institutes of Health supported this research.

According to the World Health Organization (WHO), more than three million premature deaths each year can be attributed to air pollution, with more than half of the popul
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Contact: Sherri L. Kirk
Sherri.Kirk@osumc.edu
614-293-3737
Ohio State University
Source:Eurekalert

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