Navigation Links
ORNL's newly licensed neutron detector will advance human disease research
Date:9/6/2012

A neutron detector developed for studies focused on life science, drug discovery and materials technology has been licensed by PartTec Ltd. The Indiana-based manufacturer of radiation detection technologies is moving the technology developed at the U.S. Department of Energy's Oak Ridge National Laboratory toward the commercial marketplace.

The Neutron-Sensitive Anger Camera allows researchers to study a wider variety of crystalline structures, supporting studies in biology, earth science, geology, materials science and condensed matter physics.

"This ORNL detector system, developed for DOE's Spallation Neutron Source, can determine the time and position of the neutrons captured, enabling extremely accurate neutron time-of-flight measurements," said Yacouba Diawara of the Instrument and Source Design Division at ORNL.

The detector achieves very high efficiency, high timing and position resolution and low background noise at a reduced cost all characteristics that make it attractive for medical, biological and general scientific research.

"The detector is suited for biological samples because the protein crystals scientists are interested in are very small, about the size of a grain of sand," said Richard Riedel of the Instrument and Source Design Division at ORNL. "No other neutron detectors are suited for viewing these complex proteins at a pulsed neutron source."

The ORNL research team optimized an existing technology called the Anger Camera named after its inventor, Hal Oscar Anger by improving the detector's ability to view the atomic structure of crystals, such as those composed of protein macromolecules.

Previous neutron detectors struggled to resolve crystals smaller than 2 millimeters, but ORNL's system can clearly detect 1-millimeter and smaller crystals. This capability is important not only for biological crystals but also for small crystals that are subject to extremely high pressures using an instrument at SNS called the Spallation Neutron and Pressure Diffractometer.

"It turns out there are a number of proteins and enzymes that don't form very large crystals," Riedel said. "The push in neutron science has been to design devices that can detect smaller and smaller crystals down to half a millimeter."

PartTec CEO Herschel Workman envisions this technology greatly impacting a variety of scientific fields. The advances in biological research alone could affect the development of novel drugs for many types of disease.

"We are pleased to receive this opportunity to manufacture and market the Anger Camera, which will help researchers expand current medical boundaries," Workman said. "Their work, in turn, will help those in need to find medical answers and options previously unavailable to them."


'/>"/>

Contact: Jennifer Brouner
brounerjm@ornl.gov
865-241-9515
DOE/Oak Ridge National Laboratory
Source:Eurekalert

Related biology news :

1. U of M researchers: Newly discovered genetic markers could signal colon cancer development
2. Newly discovered dinosaur implies greater prevalence of feathers
3. Newly discovered breast milk antibodies help neutralize HIV
4. Key proteins newly discovered form and function may provide novel cancer treatment target
5. Scientists advance field of research with publication of newly validated method for analyzing flavanols in cocoa
6. Newly found protein helps cells build tissues
7. Newly discovered foot points to a new kid on the hominin block
8. Scripps Research discoveries lead to newly approved drug for infant respiratory distress syndrome
9. Newly released FDA draft guidelines for biosimilar drugs to be discussed at conference
10. Ultracold matter technology from CU and SRI International licensed to Boulders ColdQuanta
11. RIT leads development of next-generation infrared detectors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/30/2016)... , Nov. 30, 2016 Not many of us realize that we ... of recovery so we need to do it well. Inadequate sleep levels have been ... blood pressure, stroke, diabetes, and even cancer. Maybe now is the best ... that could help them to manage their sleep quality? ... ...
(Date:11/29/2016)... BOSTON , Nov. 29, 2016 BioDirection, ... rapid point-of-care products for the objective detection of concussion ... the company has successfully completed a meeting with the ... company,s Tbit™ blood test Pre-Submission Package. During the meeting ... Tbit™ system as a precursor to commencement of a ...
(Date:11/29/2016)... CANNES, France , November 29, 2016 Nearly ... Continue Reading ... ... System is part of an efficient Identity Management. (PRNewsFoto/DERMALOG Identification Systems) ... DERMALOG is Germany's largest Multi-Biometric ...
Breaking Biology News(10 mins):
(Date:12/8/2016)... 2016 Oxford Gene Technology ... NGS panel range with the launch of the SureSeq myPanel™ ... of variants in familial hypercholesterolemia (FH). The panel delivers single ... a single small panel and allows customisation by ,mix and ... exons for LDLR , P C ...
(Date:12/8/2016)... Worcester, Mass (PRWEB) , ... December 08, 2016 ... ... KbioBox genetic data bioInformatics portal. In response to client demand KbioBox developed a ... gene edit biodesign program. Both are accessible from KBioBox’s new website, https://www.kbiobox.com/ ...
(Date:12/8/2016)... Francisco, CA (PRWEB) , ... December 08, 2016 ... ... Oculus as finalists in the World Technology Awards. uBiome is one of just ... received across all categories. , In addition to uBiome, companies nominated as finalists ...
(Date:12/8/2016)... , Dec. 8, 2016  Soligenix, Inc. (OTCQB: ... company focused on developing and commercializing products to ... medical need, announced today the long-term follow-up data ... (dusquetide), a first-in-class Innate Defense Regulator (IDR), in ... and neck cancer patients undergoing chemoradiation therapy (CRT).  ...
Breaking Biology Technology: