Navigation Links
ORNL story tips, February 2012
Date:2/14/2012

ornl.gov">wallira@ornl.gov]

NEUTRONS -- Analyzing the antibacterial assault . . .

A combination of advanced techniques at Oak Ridge National Laboratory helped researchers gain a better understanding of how some proteins attack bacteria. Colicins, a family of protein toxins, kill E. coli by crossing the bacterial membrane to exert their toxic effects. One family member, Colicin N, utilizes outer membrane protein F, or OmpF, to penetrate the bacterial membrane. Since neutron scattering alone cannot differentiate between the complex formed between Colicin N and OmpF in membranes, University of Newcastle scientists collaborated with Kevin Weiss in the Center for Structural Molecular Biology's Bio-Deuteration Laboratory to label OmpF with deuterium. This allowed the individual proteins to be selectively highlighted in neutron scattering experiments, a critical step in determining how colicins cross the membrane barrier. Results from these experiments support the hypothesis that Colicin N penetrates the E. coli membrane at the perimeter of OmpF and reveal possible new routes for antibiotics to enter bacteria. [Written by Emma Macmillan; media contact: Ron Walli, (865) 576-0226; wallira@ornl.gov]


'/>"/>

Contact: Ron Walli
wallira@ornl.gov
865-576-0226
DOE/Oak Ridge National Laboratory
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Bonobos unusual success story
2. Nobel history illustrates gap in grants to young scientists
3. Earths massive extinction: The story gets worse
4. Story of lymphatic system expands to include chapter on valve formation
5. Story tips from the US Department of Energys Oak Ridge National Laboratory, November 2011
6. Story tips from the Department of Energys Oak Ridge National Laboratory, October 2011
7. What makes rainforests unique? History, not ecology
8. Using human genomes to illuminate the mysteries of early human history
9. Mouse genome sequences reveal variability, complex evolutionary history
10. Sea smarts: Scientists reconstruct evolutionary history of mollusks
11. The remarkable history of medicines battle with infectious diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2014)... CIE San Diego has launched an innovative ... tissue that enhances care coordination among social service and ... information; earned a second $1 million grant from the ... aging in community and; will be recognized as a ... 4-6p. CIE San Diego today announced ...
(Date:12/10/2014)... , December 9, 2014 ... ITN,s BCARD Platform   ... enterprise meeting scheduling solutions for business-to-business (B2B) events, ... world leader in mobile near-field communication (NFC), Bluetooth ...      (Logo: http://photos.prnewswire.com/prnh/20140612/691055) , Jifflenow ...
(Date:12/5/2014)... 2014  Tute Genomics, a leader in cloud-based solutions ... A1 funding led by UK-based Eurovestech. Peak Ventures and ... investment round. "We are at a pivotal ... sequencing and seeks new approaches for the diagnosis, treatment ... MD MBA, and CEO of Tute Genomics. "One of ...
Breaking Biology News(10 mins):Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 3Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 2Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 3
... today to the late Ernest Geskin, PhD, of Florham Park, ... professor at NJIT for more than 25 years. Sharing the ... and now a senior mechanical engineer for Marotta Controls, Montville. ... Forming of Tubular Parts" discloses a method for using propellant ...
... study finds that stroke patients, brains show strong cortical motor ... that offers new insight into stroke rehabilitation. Using functional ... monitored the brains of 24 individuals 12 who had ... as they watched others performing actions made using the arm ...
... 11, 2013 (BRONX, NY) Today, researchers at ... University convened a one-day conference on Jewish genetics designed ... Such research could help scientists identify causes and potential ... disorders afflicting the general population. The genetic ...
Cached Biology News:Patent awarded today to NJIT for novel use of water jets to create high tensile strength alloy parts 2Exercise for stroke patients' brains 2Albert Einstein College of Medicine hosts conference on Jewish genetic research 2
(Date:12/13/2014)... SAN ANTONIO , Dec. 12, 2014 /PRNewswire/ ... presentation of data at the San Antonio Breast Cancer ... epoetin alfa plus best supportive care (BSC) versus BSC ... breast cancer receiving standard chemotherapy. This non-inferiority trial did ... out a 15 percent or greater increase in the ...
(Date:12/12/2014)... December 11, 2014 Graphite Metallizing Corporation, ... for pumps and process equipment, has appointed Kirk Staller ... and Ontario, Canada. Staller holds a B.S. degree from ... the industrial market place, much of it with a ... of his Michigan office. , “We are ...
(Date:12/12/2014)... 11, 2014 Electronic Data Interchange ... claims management and supply chain management to depend ... transactions. The benefits associated with the use of ... of transactions has helped improve the acceptance of ... 70 market data tables and 107 figures spread ...
(Date:12/12/2014)... MA (PRWEB) December 11, 2014 ... delivery products for ophthalmology and wound care applications. ... LayerBio a $150,000 small business innovation research grant ... , Glaucoma is the leading cause of irreversible ... 2.2 million people suffer from glaucoma. The ...
Breaking Biology Technology:Data from the EPO-ANE-3010 Study Evaluating Epoetin Alfa Presented at San Antonio Breast Cancer Symposium 2Data from the EPO-ANE-3010 Study Evaluating Epoetin Alfa Presented at San Antonio Breast Cancer Symposium 3Data from the EPO-ANE-3010 Study Evaluating Epoetin Alfa Presented at San Antonio Breast Cancer Symposium 4Data from the EPO-ANE-3010 Study Evaluating Epoetin Alfa Presented at San Antonio Breast Cancer Symposium 5Data from the EPO-ANE-3010 Study Evaluating Epoetin Alfa Presented at San Antonio Breast Cancer Symposium 6Data from the EPO-ANE-3010 Study Evaluating Epoetin Alfa Presented at San Antonio Breast Cancer Symposium 7Data from the EPO-ANE-3010 Study Evaluating Epoetin Alfa Presented at San Antonio Breast Cancer Symposium 8Data from the EPO-ANE-3010 Study Evaluating Epoetin Alfa Presented at San Antonio Breast Cancer Symposium 9Data from the EPO-ANE-3010 Study Evaluating Epoetin Alfa Presented at San Antonio Breast Cancer Symposium 10Data from the EPO-ANE-3010 Study Evaluating Epoetin Alfa Presented at San Antonio Breast Cancer Symposium 11Data from the EPO-ANE-3010 Study Evaluating Epoetin Alfa Presented at San Antonio Breast Cancer Symposium 12Kirk Staller Joins Graphite Metallizing Corporation 2The Global EDIS Market Was Valued at $312.00 Million in 2014 - New Report by MarketsandMarkets 2The Global EDIS Market Was Valued at $312.00 Million in 2014 - New Report by MarketsandMarkets 3The Global EDIS Market Was Valued at $312.00 Million in 2014 - New Report by MarketsandMarkets 4MIT Spinoff Receives NSF Grant to Develop Nanoparticle Glaucoma Therapy 2
... Mentice, Inc. and MATC have,forged a relationship ... on multiple,and mutually beneficial projects to further advance ... institutions throughout North America., Mentice,s Procedicus VIST ... attending physician to gain exposure to routine,and sophisticated ...
... Best-Selling Author to Devote Energies to Raising Awareness and Funds ... Cancers, Neurological, ... Other Serious Medical Conditions, CHARLOTTESVILLE, Va., Aug. 13 ... the development and,adoption of a breakthrough therapeutic technology -- Magnetic ...
... Inc.,(Nasdaq: ATSI ), manufacturer and marketer of ... participate at the Fourth,Annual Noble Financial Equity Conference ... Chief Financial Officer of ATS Medical, will,present at ... 2008., (Logo: http://www.newscom.com/cgi-bin/prnh/20040202/ATSILOGO ), Attendance ...
Cached Biology Technology:Mentice, Inc. and the Milwaukee Area Technical College (MATC) Announce Their Partnership in the Area of Procedural Medical Simulation 2John Grisham Joins Focused Ultrasound Surgery Foundation Board, Citing Novel Technology's Potential to Help 'Millions of Patients' 2John Grisham Joins Focused Ultrasound Surgery Foundation Board, Citing Novel Technology's Potential to Help 'Millions of Patients' 3ATS Medical to Participate at the Fourth Annual Noble Financial Equity Conference 2
Request Info...
We offer solid and solution phase peptide synthesis including a whole range of modifications. Please send the details of your peptide synthesis need to info@rpeptide.com...
Maxi 14 Hybridization Oven. 14 bottle (35 mm) rotisserie + shaker tray available for simultaneous use. Includes linear and orbital shaker trays, 4 medium bottles, pack of mesh, bottle gripper and d...
Request Info...
Biology Products: