OHSU turns innovations into commercial opportunities at r...(mpany is perfecting a proprietary method...)

Date:10/23/2007

mpany is perfecting a proprietary method of local drug delivery at the blood-graft interface that minimizes the side effects associated with other drug delivery systems used for these applications. Hanson holds 18 patents and has founded four companies. His most recent venture, Revitus, was focused on developing two novel extended-release drug compounds for preventing heart attacks, thrombotic strokes and death in patients who are at risk of adverse cardiovascular events. Revitus was acquired earlier this year by BioVascular, Inc., a privately held San Diego biotechnology company.

• Portland Bioscience, Inc. ( PdxBio ) is a privately owned molecular diagnostics and health information technology company. It provides proprietary software and hardware solutions to facilitate the emergence of personalized medicine, which involves the prescription of specific drugs or other therapeutic agents based on an individuals unique genomic composition or genotype. The companys proprietary genomic analysis, assay design and engineering tools are aimed at developing assays capable of positively determining such individual genotypes. PdxBio has an exclusive license with OHSU to clinical materials from the laboratory of Cheryl Maslen, Ph.D., OHSU professor of medicine and molecular and medical genetics. A major focus of Maslens lab is the study of metastasis of cancer cells. A mutation in the CRELD1 gene, which codes for a cell surface adhesion protein, has been identified by Maslen as a potential indicator of metastatic activity. PdxBio will develop commercial assays to test for the presence or absence of this mutation in clinical samples. Maslen also is working with the company to develop a diagnostic SNP (single nucleotide polymorphism) assay for detection of age-related macular degeneration, the leading cause of vision loss in developed countries. [ For more information about Portland Bioscience, go to htt
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Contact: Harry Lenhart lenharth@ohsu.edu 503-494-8231 Oregon Health & Science University Source:Eurekalert

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