Navigation Links
OHSU discovery may someday lead to prevention and treatment of sudden infant death syndrome
Date:2/16/2012

Researchers at Oregon Health & Science University have discovered that brain cells commonly thought to play a supporting role actually are critically important for the growth of brainstem neurons responsible for cardiorespiratory control. The discovery has profound implications for the prevention and treatment of SIDS (Sudden Infant Death Syndrome), the leading cause of death in children aged one month to one year.

The new discovery is published online in Neuroscience: http://www.sciencedirect.com/science/article/pii/S0306452212000358

In their study, the OHSU team looked at glial cells, non-neuronal cells of the brain, and found that they very potently regulate growth of nerve cells in the brainstem. In fact, the glial cells actually inhibit the growth of brainstem neurons and may be as important for establishing neuronal networks as neurotrophic factors, a family of proteins essential for brain growth and survival. The OHSU study is the first to find that glial cells inhibit nerve cell growth.

"Previous research has shown that a common feature of the brains of SIDS babies is a dramatically increased number of glial cells," said Agnieszka Balkowiec, M.D., Ph.D., principal investigator and associate professor of integrative biosciences in the OHSU School of Dentistry. "Based on the results of our new study, the increase in glial cells in SIDS babies could be the cause of a compromised growth of brainstem neurons that control the cardiorespiratory function and, ultimately, cause death."

The new study also shows that glial cells direct the growth of brainstem neurons caused by BDNF (Brain-Derived Neurotrophic Factor), another molecule found by the Balkowiec lab to play an important role in cardiorespiratory control.

"Our study shows that the picture is more complex than we had previously thought,"
'/>"/>

Contact: Sydney Clevenger
clevenge@ohsu.edu
Oregon Health & Science University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Notre Dame researchers report fundamental malaria discovery
2. Discovery of plant nourishing gene brings hope for increased crop seed yield and food security
3. Discovery could help stem smoking-related diseases
4. Georgetown researchers lead discovery expected to significantly change biomedical research
5. New horned dinosaur announced nearly 100 years after discovery
6. Researchers awarded $3.2 million from NIH to pioneer advanced biomolecule discovery technology
7. UGA discovery changes how scientists think about plant cell wall formation
8. Discovery of therapeutic peptides affecting mitochondria
9. ORNL fundamental discovery casts enzymes in new light
10. Scripps research team achieves critical step to opening elusive class of compounds to drug discovery
11. Discovery of new gene could improve efficiency of molecular factories
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2014)... CIE San Diego has launched an innovative ... tissue that enhances care coordination among social service and ... information; earned a second $1 million grant from the ... aging in community and; will be recognized as a ... 4-6p. CIE San Diego today announced ...
(Date:12/5/2014)... 4, 2014 Increased emphasis on product ... new testing and inspection technologies. The convergence of ... a range of innovative test solutions. This trend ... Y, which is generally more inclined towards communication, ... development strategies of test equipment vendors will cater ...
(Date:12/3/2014)...   Marvin Test Solutions , a trusted ... military, aerospace, and manufacturing organizations, today announced the ... TS-900 PXI semiconductor test platform . The TS-960 ... to customers at a fraction of the footprint ... "Our semiconductor customers asked for ...
Breaking Biology News(10 mins):Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 3
... France suggests that Neandertals may have become regionally mobile ... colleagues from Université Bordeaux 1 in France, Max Planck ... conclude that the human femur fragment found in 2002 ... Neandertal, based on its shape and mitochondrial DNA. Its ...
... used to reduce the risk of stomach ulcers in people ... after miscarriage, according to a study by researchers at the ... National Institutes of Health and other research institutions. , The ... of Medicine. , The drug, misoprostol, has been used to ...
... have reported findings that offer a surprising new twist ... pollinator, select the flowers from which they collect nectar. ... choose flowers entirely alone but instead copy the choices ... adjust their behavior when dealing with flowers of unfamiliar ...
Cached Biology News:Neandertal femur suggests competition with hyenas and a shift in landscape use 2Sleeping Sickness Epidemic Spreading in Uganda 2Sleeping Sickness Epidemic Spreading in Uganda 3Sleeping Sickness Epidemic Spreading in Uganda 4
(Date:12/24/2014)... New York (PRWEB) December 23, 2014 According ... the Long Island Affiliate of ITRA Global, the national office ... but steady recovery. This is evidenced by the third ... strong stock market. Low energy costs have held inflation ... The only negative is the housing market remaining soft. , ...
(Date:12/24/2014)... Nashville, Tenn. (PRWEB) December 23, 2014 ... Hill was elected treasurer for the American Society ... to advancing knowledge and research in reproductive medicine. ... fills a seat on the executive board and will ... , Dr. Hill has actively supported ASRM since ...
(Date:12/24/2014)... San Diego, CA (PRWEB) December 23, 2014 ... Contest where their Twitter followers can submit their ... for themselves and their lab mates. , For those ... beloved lab mates, the Pipette.com Holiday in the Lab ... encourages Pipette.com Twitter followers to send pictures ...
(Date:12/24/2014)... , Dec. 23, 2014 Vermillion, ... focused on gynecologic disease, announced today that investors ... , Birchview Fund LLC and several Vermillion directors ... unregistered shares of Vermillion,s common stock and warrants ... in a private placement.  Under ...
Breaking Biology Technology:ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3Major Pipette Distributor Pipette.com Announces their Holiday in the Lab Contest 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 4Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 5
... Corporation,s (NYSE AMEX LLC: ETC) ("ETC" or the ... of Mr. Ray Wyngarden as Western Regional Sales ... expanding market awareness of the BARA-MED(R) XD Monoplace ... the western portion of the United States.Mr. Wyngarden,s ...
... Group at Frost & Sullivan is ... Presentation on the Global Active Pharmaceutical Ingredients (API) ... 2009, at 3 p.m. GMT.(Logo: http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO )The ... is currently witnessing a rapid shift towards biopharmaceuticals. ...
... Traditional Cardiac Safety Approaches , ... ... a leading innovator in advanced cardiac safety biomarkers and automated ... of pharmaceutical companies, biotechnology companies and industry consultants. When ...
Cached Biology Technology:Environmental Tectonics Corporation Expands BioMedical Systems Division Sales Staff 2Environmental Tectonics Corporation Expands BioMedical Systems Division Sales Staff 3The Global Active Pharmaceutical Ingredients (API) Market: A Frost & Sullivan Briefing on Changing Dynamics 2The Global Active Pharmaceutical Ingredients (API) Market: A Frost & Sullivan Briefing on Changing Dynamics 3Avoiding False Positives Key Priority in Cardiac Safety Studies 2
Request Info...
Ultra-sensitive, non-radioactive detection of rat Osteopontin...
Request Info...
Agarose-LE, 500 g. Suitable for soft agarose cloning. Nuclease-free.Gel point (1.5%): 36 1.5 C, EEO (-mr): 1200 g/cm2. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Biology Products: