Navigation Links
OGI invests in drug discovery at InDanio Bioscience
Date:10/19/2010

new therapeutic avenues into the NR family."

InDanio's zebrafish ligand trap (LT) technology and LT drug discovery platform will take advantage of the fact that zebrafish are transparent in early stages of development, thus allowing for the use of fluorescent protein markers. Many drugs never reach the marketplace because they fail toxicology tests or have other unintended effects on the body. Currently, in vitro testing relies on measuring simple chemical interactions to gauge a drug's effectiveness, but this is often not an effective predictor of how drugs will affect living organisms. By beginning the screening process with in vivo assays using live zebrafish, more information on a drug's effectiveness, toxicology and other side-effects can be gathered in advance of and to better inform downstream clinical trials.

"InDanio is in an excellent position to capitalize on the significant work undertaken by the academic and pharma sectors over the past 20 years in characterizing NR proteins and developing compound libraries targeting these proteins," commented Dr. Christian Burks, President and CEO of OGI. "Their screening system should provide novel, productive information on natural ligands, tissue and developmental specificity of natural or xenobiotic compounds, and whether or not a compound binds multiple receptors."


'/>"/>

Contact: Alastair Harris-Cartwright
aharriscartwright@ontariogenomics.ca
416-673-6582
Ontario Genomics Institute
Source:Eurekalert

Page: 1 2

Related biology news :

1. JPMorgan Chase & Co., Invests $25,000 to Support Bring Me A Books San Jose Elementary School Library Initiative
2. Finland invests €1.85 million in pan-European infrastructure for biomedical research
3. University of Plymouth invests in dental research
4. NIGMS invests in scientific Grand Opportunities with Recovery Act funds
5. Texas invests record $3.5 million in startup cofounded by UTs Mauro Ferrari
6. T cell discovery shows promise for Type 1 diabetes treatment: UBC-CFRI study
7. Research breakthrough hailed on the anniversary of gene discovery
8. Discovery of a cell that suppresses the immune system
9. Census of Marine Life celebrates decade of discovery
10. Discovery of key pathway interaction may lead to therapies that aid brain growth and repair
11. Biofuel from inedible plant material easier to produce following enzyme discovery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... ("Company") (BM&FBOVESPA: VLID3 ON), is pleased to inform its shareholders ... Washington,s Department of Licensing, in the United States, awarded ... for driver,s licenses and identification cards to its subsidiary, Valid ... start in January 2015, with enrollment and card production starting ...
(Date:1/22/2015)... MADISON, Wis. , Jan. 15, 2015  BellBrook ... for drug discovery, announced the launch of a ... of the company,s Transcreener UDP Assay, a high ... enzymes. The new assay will allow for sensitive ...
(Date:1/22/2015)... YORK , Jan. 21, 2015  Analyst Report Issued by ... Card Brands report showed that planet-wide, transactions at merchants on ... while the total number of credit, debit, and prepaid cards ... U.S. were victims of fraudulent card usage in 2012, and ...
Breaking Biology News(10 mins):Valid USA Signs Contract For Washington Driver's License Issuance 2BellBrook Labs Launches a High Throughput Screening Assay for Glycosyltransferases with TR-FRET Readout 2$4.80 Near Term Price Target with "Buy" given by CapRock Research for NXT-ID, Inc. (NASDAQ: NXTD) issued by Small Cap IR 2
... Scientists at Case Western Reserve University School of Medicine ... that grow into the protective myelin coating on nerves in ... treatments for multiple sclerosis, cerebral palsy and other demyelinating diseases ... published in the online issue of Nature Methods , ...
... Ibuprofen, naproxen, and related non-steroidal anti-inflammatory drugs (NSAIDs) ... still have some secrets to reveal about how ... new insights into the actions of NSAIDs. Their ... raise the possibility of developing a new class ...
... Chalmers University of Technology have built a very simple ... directions, even though the antenna is smaller than the ... online journal Nature Communications this week ... very low concentrations of gases or biomolecules. A ...
Cached Biology News:Mice stem cells guided into myelinating cells by the trillions 2Mice stem cells guided into myelinating cells by the trillions 3Study puts a new spin on ibuprofen's actions 2Bimetallic nanoantenna separates colors of light 2
(Date:12/25/2014)... The report “Service Quality Management and Telco ... Type - Global Advancements, Worldwide Forecasts & Analysis (2014-2019)” ... and forecasting of revenues. , Browse 152 market ... in-depth TOC on “Service Quality Management (SQM) and Telco ...
(Date:12/24/2014)... DALLAS and NEW YORK , ... a biopharmaceutical company advancing patient care in critical areas, announced ... of common stock, and warrants to purchase up to an ... of $4.00 per share and $.01 per warrant.  The warrants ...
(Date:12/24/2014)... BOTHELL, Wash. , Dec. 24, 2014   BioLife Solutions ... manufacturer and marketer of proprietary clinical grade hypothermic storage ... thermal shipping products for cells and tissues  ("BioLife" or ... Annual Meeting of Stockholders on May 4, 2015 (the "Annual ...
(Date:12/24/2014)... 23, 2014 GMO corn cases filed across ... in the process of being consolidated in a Kansas federal ... Syngenta AG MIR 162 Corn Litigation, MDL No. 2591 in ... Management of the Syngenta GMO corn multidistrict litigation (MDL) has ...
Breaking Biology Technology:Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 2Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 3Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 4PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 3BioLife Solutions Sets Date for Annual Meeting of Stockholders 2Carey Danis & Lowe Reports on Syngenta GMO Corn Transfer Order 2
... Wis. - As law professors at major universities, Rebecca ... case perfectly clear: they are not calling for repeal of ... patent their inventions. They are advocating an adjustment that ... University of Michigan and Rai of Duke University ...
... - An agreement struck to accelerate the transformation of ... visions of a medical discovery triangle connecting Milwaukee, Madison, ... milestone in the drive to facilitate scientific collaboration and ... formally joined forces with WiSys Technology Foundation, Inc. ...
... Madison, Wis. - Quick quiz: Which Wisconsin institutions spend ... , ,Naming No. 1 is relatively easy: the University ... academic R&D centers in the United States. Second on the ... million), which ranks among the nation's top 100 medical research ...
Cached Biology Technology:Professors want to tweak, not overhaul, patent law 2Professors want to tweak, not overhaul, patent law 3WiSys to patent Marshfield Clinic discoveries 2Marshfield Clinic and UW combine to speed tech growth 2Marshfield Clinic and UW combine to speed tech growth 3Marshfield Clinic and UW combine to speed tech growth 4
Goat polyclonal to T7 tag (Agarose) Immunogen: Goats were immunized with MASMTGGQQMG (T7) conjugated to KLH.After multiple immunizations in Freund's adjuvant, serum was collected....
Insect Cell Lysis Buffer 50 ml...
Mouse monoclonal [11C9] to Zeralenone ( Abpromise for all tested applications). Antigen: Chemical / Small Molecule conjugated to BSA: Zeralenone...
Fas-ligand rabbit polyclonal antibody...
Biology Products: