Navigation Links
OGI genomics researchers awarded $23 million
Date:5/9/2011

f genetic changes that underlie disease," commented Dr. McKerlie. "This funding from Genome Canada supports a leading role for Canada within an international program to understand the function of all 20,000 genes in the genome and builds on the successes of the original NorCOMM project started in 2006. NorCOMM focused on developing and distributing a library of mouse embryonic stem cell lines carrying single gene trapped or targeted mutations across the mouse genome. This new NorCOMM2 project will let us put that resource to work to understand the function of those genes in normal biology and disease."

The team, consisting of Canadian and UK researchers, will study the developmental problems and diseases that occur in 280 mouse models over the next three years. Each of the mouse models contain one abnormal or mutated gene and the team will ascertain the effect of each mutation to identify the function of the gene, and determine whether that gene, or the protein it produces, could be a drug target or used in a diagnostic test.

The third project, with a budget of nearly $10 million, is led by Drs. Sachdev Sidhu, Associate Professor, and Charles Boone, Professor, Banting and Best Department of Medical Research, University of Toronto, and will work towards developing a process and infrastructure for efficient and large-scale production of synthetic antibody reagents to target cancer and other devastating diseases.

This project will ultimately yield candidate therapeutic antibodies for commercialization by targeting in excess of 100 secreted proteins that are associated with cancer. The market for antibody therapeutics is expected to reach $26 billion this year.

"This funding will allow our team, consisting of leading cancer biologists from the Toronto research community, to generate and validate hundreds of antibodies against a host of cancer-associated targets," commented Dr. Sidhu. "These antibodies will be powerful tools for di
'/>"/>

Contact: Alastair Harris-Cartwright
aharriscartwright@ontariogenomics.ca
416-673-6582
Ontario Genomics Institute
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Broad Institute awarded major grant to bolster epigenomics research
2. Complete Genomics launches, becomes worlds first large-scale human genome sequencing company
3. Genetic Engineering & Biotechnology News reports on the trend toward predictive toxicogenomics
4. Computation and genomics data drive bacterial research into new golden age
5. New gene variants present opportunities in nutrigenomics
6. Nutrigenomics -- developing personalized diets for disease prevention
7. Human genomics in China
8. Mixing genomics and geography yields insights into life and environment
9. Comparative genomics reveals molecular evolution of Q fever pathogen
10. Complete Genomics releases proof-of-concept data for its sequencing technology for the first time
11. Venter, Somerville and Church highlight DOE/JGI genomics of energy and environment meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... Stem cells in bone marrow need to produce hydrogen ... tissue, according to a new study from the Center ... of Dentistry of USC. , Professor Songtao Shi, principal ... sulfide produced by the cells governs the flow of ... cellular signals that results in osteogenesis, or the creation ...
(Date:4/17/2014)... German . ... demanded of him, he can expect his premises to be ... of the consequences is enough to make restaurant owners pay ... lay their eggs in other birds, nests. If the host ... their revenge by destroying the entire nest. Consequently, it is ...
(Date:4/17/2014)... France have hit on a novel method to ... correct and most effective treatment possible., Kidney stones ... and developing world. If left untreated, apart from ... failure and other complications. In many patients treated ... a more effective pathological approach to diagnosis and ...
Breaking Biology News(10 mins):Fear of the cuckoo mafia 2Fear of the cuckoo mafia 3
... Humans have used the papyrus sedge for millennia. The Ancient ... buoyant boats, it is grown for ornamentation and parts can ... of Environmental Technology and Management , researchers in Uganda have ... toxins and other noxious residues from abattoir effluent. Robinson ...
... A team of UC Davis scientists has found that ... combat cancer by cutting off the supply of oxygen and ... The scientists report their discovery in the ... ). The groundbreaking study was a collaboration among multiple UC ...
... especially in rural areas, may interfere not only with ... finding flowers, according to researchers from Penn State and ... to perniciously alter key interactions between plants and animals," ... Environmental Research Letters . The animal tested in this ...
Cached Biology News:Papyrus plant detox for slaughterhouses 2Fatty acid metabolite shows promise against cancer in mice 2Fatty acid metabolite shows promise against cancer in mice 3Ozone masks plants volatiles, plant eating insects confused 2
(Date:1/15/2014)... , January 15, 2014 A study has ... on the Formula 1 track could help to tackle the ... Technologies (MAT), Stowhealth (a GP surgery based in Stowmarket) and ... provider Simplyhealth. Telemetry technology, which is inspired by ...
(Date:1/15/2014)... 15, 2014 Two champions of science, ... sponsorship of an annual competition for middle and high ... to, innovative STEM study. The competition presents students with ... of Engineering Aptitude, Mathematics, and Sciences is a ...
(Date:1/15/2014)... DTS Language Services, Inc . is pleased to ... Science organizations who need document translations. Clients will now ... documents in advance with a selection of nearly 50 life ... a critical factor in clinical and scientific fields, and decrease ...
(Date:1/15/2014)... Sunnyvale, CA (PRWEB) January 15, 2014 ... throughput research solutions, today announced that Lupin Limited, one ... of Freeslate’s CM Protégé PharmD System for ... in Mumbai, India, is focused on a wide range ...
Breaking Biology Technology:Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5DTS Improves Efficiency for Life Science Document Translations 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3
... mission statement, consider this pledge from the bipartisan Wisconsin School ... dollars on top of current dollars, but propose a complete ... the (K-12 public school) system, and then any additional dollars ... , [Tom Still is a member of the initiative] ...
... President George Bush today spoke of energy during ... traditional energy resources, his remarks were directed toward new ... to foreign oil. , ,In an address before employees ... is developing a new fuel cell for hybrid automobiles, ...
... Eau Claire, Wis. The Eau Claire Area ... again, offering cash awards of up to $10,000 to the ... entrepreneurs, the EDC is holding a business planning seminar on ... Business Contest will have until May 26 to prepare ...
Cached Biology Technology:Measuring what works and what doesn't in the prototypical school 2Measuring what works and what doesn't in the prototypical school 3Bush praises Johnson Controls battery tech in Milwaukee visit 2
... a powerful technology platform that automates gel ... High quality sample preparation can be carried ... Xcise is a powerful technology platform that ... analysis. It combines the functions of high-resolution ...
Request Info...
... compatible with hood installations. ... system for 384-well plates, ... prepares large quantities of ... Wellpro also performs plate ...
... is a new generation bulk reagent dispenser ... simplicity for pharmaceutical and biotech laboratories. Based ... range, Multidrop Combi has been designed for ... 0.5-2500 l and multiple plate types including ...
Biology Products: