Navigation Links
Nutrient in eggs and meat may influence gene expression from infancy to adulthood
Date:9/20/2012

ntinue to have a long-lasting influence on adult life," said Eva K. Pressman, M.D., study author and director of the high-risk pregnancy program at the University of Rochester Medical Center. "While our results won't change practice at this point, the idea that maternal choline intake could essentially change fetal genetic expression into adulthood is quite novel."

Pressman, who advises pregnant women every day, says choline isn't something people think a lot about because it is already present in many things we eat and there is usually no concern of choline deficiency. Though much more research has focused on folate functionally very similar to choline and used to decrease the risk of neural tube defects like spina bifida a few very compelling studies sparked her interest, including animal studies on the role of choline in mitigating fetal alcohol syndrome and changing outcomes in Down syndrome.

A long-time collaborator with researchers at Cornell, Pressman joined a team led by Marie Caudill, Ph.D., R.D., professor in the Division of Nutritional Sciences at Cornell, in studying 26 pregnant women in their third trimester who were assigned to take 480 mg per day, an amount slightly above the standard recommendation of 450 mg per day, or about double that amount, 930 mg per day. The choline was derived from the diet and from supplements and was consumed up until delivery.

The team found that higher maternal choline intake led to a greater amount of DNA methylation, a process in which methyl groups one carbon atom linked to three hydrogen atoms are added to our DNA. Choline is one of a handful of nutrients that provides methyl groups for this process. The addition of a single methyl group is all it takes to change an individual's epigenome.

Measurements of cord blood and samples from the placenta showed that increased choline, via the addition of methyl groups, altered epigenetic markers that govern cortisol-regulating genes
'/>"/>

Contact: Emily Boynton
emily_boynton@urmc.rochester.edu
585-273-1757
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Research on flavanols and procyanidins provides new insights into how these phytonutrients may positively impact human health
2. Consumers need simple, concise messages about benefits of phytonutrients
3. Nutrient and toxin all at once: How plants absorb the perfect quantity of minerals
4. Obtaining key nutrients from canned foods can save consumers money
5. Prenatal micronutrient, food supplementation intervention in Bangladesh decreases child death rate
6. Study: No-fat, low-fat dressings dont get most nutrients out of salads
7. U OF A expert pinpoints nutrient behind fresh water algae blooms
8. Increased sediment and nutrients delivered to bay as Susquehanna reservoirs near sediment capacity
9. Circadian rhythms have profound influence on metabolic output, UCI study reveals
10. BUSM researchers identify genes that influence hippocampal volume
11. Fat outside of arteries may influence onset of coronary artery disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/26/2015)... The Granite Club, ... club, today announced it has implemented a state-of-the-art access ... for members and staff, while restricting access to authorized ... selected FST,s IMID Access system because it has the ... and staff, in addition to unparalleled security," said ...
(Date:3/24/2015)... 24, 2015 Research and Markets ( http://www.researchandmarkets.com/research/kvdtcw/face_and_voice ) ... - Global Strategic Business Report" report to their offering. ... Biometrics in US$ Thousands by the following Segments: Face Biometrics, and ... Canada , Japan , ... Middle East & Africa , and ...
(Date:3/24/2015)... GARDENS, Fla. , March 24, 2015 /PRNewswire/ ... identity management solutions, today announced that its U.are.U ... clothing accessory retailer Goorin Bros . to ... Crossmatch biometrics-based solution secures access to the POS ... the increased risk of data breaches. ...
Breaking Biology News(10 mins):Granite Club First Private Club in North America to Implement FST Biometrics Secure Access Solution, as Part of Multi-million Dollar Expansion 2Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 2Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 3Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 4Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 5Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 6Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2
... Department of Energy,s (DOE),s National Renewable Energy Laboratory ... Capital (SAPC) working group with a mission to ... cash flows in the marketplace. SAPC,s primary ... agreements, leases, and other documents relevant to residential ...
... , First economic models showing impact of post-weaning multi-systemic ... to 84 per pig lost, depending on severity of PMWS, ... Stark new figures show that a common pig virus, ... implications for individual farmers and the pig industry as a whole, ...
... can pass down from one generation to the next ... of genetics. Scientists have shown that an enzyme in ... changes in gene activity an example of epigenetics. ... directly affect DNA sequences. Though some evidence has suggested that ...
Cached Biology News:NREL assembles industry working group to advance solar securitization 2Pig wasting syndrome costing farmers millions 2Researchers find novel way plants pass traits to next generation 2Researchers find novel way plants pass traits to next generation 3Researchers find novel way plants pass traits to next generation 4
(Date:5/4/2015)... 2015 /PRNewswire/ - Fluorinov Pharma (Fluorinov), a FACIT ... of Dr. Roger J Garceau, to its Board ... in matters including corporate development and clinical strategy, ... significant regulatory expertise as Fluorinov transitions to clinical ... years of pharmaceutical development experience to Fluorinov and ...
(Date:5/4/2015)... PRINCETON, N.J. , May 4, 2015  Soligenix, ... biopharmaceutical company developing products that address unmet medical needs ... today that it will be presenting preclinical data from ... and Biological Defense Science and Technology Conference on May ... Convention Complex at 701 Convention Plaza, St. ...
(Date:5/4/2015)... ALISO VIEJO, Calif. , May 4, 2015 /PRNewswire/ ... to eliminate preventable hospitalizations, has teamed with the ... effect of Sentrian technology on 1,000 patients with chronic ... nearly 13 million Americans and is the nation,s third ... plan members of CareMore Health System , a ...
(Date:5/1/2015)... 1, 2015 Pfenex Inc. (NYSE MKT: ... development of biosimilar therapeutics including high value and ... first quarter 2015 financial results will be released ... of market. At 8:30 am Eastern Time, Pfenex management ... financial results and provide a business update. A press ...
Breaking Biology Technology:Roger J Garceau joins Fluorinov board, adds clinical expertise to bromodomain program and oncology pipeline 2Roger J Garceau joins Fluorinov board, adds clinical expertise to bromodomain program and oncology pipeline 3Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 2Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 3Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 4Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 5Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 6Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 7Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 8Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 9Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 10Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 11Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 12CareMore, Scripps Translational Science Institute, and Sentrian Launch Landmark Study of Remote Patient Monitoring for COPD Population 2CareMore, Scripps Translational Science Institute, and Sentrian Launch Landmark Study of Remote Patient Monitoring for COPD Population 3CareMore, Scripps Translational Science Institute, and Sentrian Launch Landmark Study of Remote Patient Monitoring for COPD Population 4CareMore, Scripps Translational Science Institute, and Sentrian Launch Landmark Study of Remote Patient Monitoring for COPD Population 5Pfenex To Report First Quarter 2015 Results and Provide Business Update on Thursday, May 14, 2015 2
... Ohio, June 22, 2011 With the intent to ... disease in Akron, the Austen BioInnovation Institute in Akron ... the conference "Healthier by Design: Creating Accountable Care Communities" ... regional health and wellness thought-leaders, the strategic discussion is ...
... Colorado Institute for Drug, Device and Diagnostic Development ... the Colorado life science ecosystem through company creation ... Veterinary Emerging Technologies Development Corporation (VetDC) to receive ... commercializes technologies to address serious unmet medical needs ...
... 2011 VENENUM Biodesign, a drug discovery company that ... to identify potential therapeutic agents against its novel disease-based ... opened its new medicinal chemistry space at 8 Black ... facility comprises over 11,000 square feet of state-of-the-art research ...
Cached Biology Technology:Austen BioInnovation Institute in Akron Begins Work on Roadmap for First U.S. Accountable Care Community 2Austen BioInnovation Institute in Akron Begins Work on Roadmap for First U.S. Accountable Care Community 3Colorado Institute for Drug, Device and Diagnostic Development Awards Funding to Fort Collins-based VetDC 2VENENUM Biodesign Announces Opening of Medicinal Chemistry Labs 2