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Nurture impacts nature: Experiences leave genetic mark on brain, behavior
Date:11/11/2013

identified a potentially new genetic mechanism, called piRNA, underlying long-term memory. Molecules of piRNA were previously thought to be restricted to egg and sperm cells (Eric Kandel, MD, see attached summary).
  • Epigenetic DNA remodeling is important for forming memories. Blocking this process causes memory deficits and stunts brain cell structure, suggesting a mechanism for some types of intellectual disability (Marcelo Wood, PhD, see attached summary).

    "DNA may shape who we are, but we also shape our own DNA," said press conference moderator Schahram Akbarian, of the Icahn School of Medicine at Mount Sinai, an expert in epigenetics. "These findings show how experiences like learning or drug exposure change the way genes are expressed, and could be incredibly important in developing treatments for addiction and for understanding processes like memory."


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  • Contact: Kat Snodgrass
    media@sfn.org
    202-962-4090
    Society for Neuroscience
    Source:Eurekalert

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