Navigation Links
Now, the story can be told - how scientists helped ID 'Amerithrax'
Date:3/8/2011

COLLEGE PARK, Md. It took nearly a decade before University of Maryland researchers were allowed to talk about their work identifying the anthrax strain used in the 2001 deadly letter attacks. But now, they and the other key members of the high-powered science team have published the first account of the pioneering work, which launched the new field of "microbial forensics" and gave bioterrorism investigators a way to "fingerprint" bacteria.

The current online Early Edition of the Proceedings of National Academy of Sciences (PNAS) <http://www.pnas.org/content/early/2011/03/01/1016657108.abstract> details the multi-institutional research that the FBI ultimately used to track anthrax-laden letters back to test tube number RMR-1029 at a lab in Fort Detrick, Maryland. University of Maryland bioinformatics experts co-authored the article and conducted the computational analysis that detected four genetic mutations that together comprised a unique signature of a particular colony of anthrax bacteria. The FBI subsequently determined this colony was found only in that Ft. Detrick test tube.

The Maryland researchers have since developed their work into a genetic 'fingerprinting' tool that is available online to law enforcement seeking to track down other microbial suspects.

"We found unique bio-markers to help investigators track down the source of the anthrax," said Steven Salzberg, director of the University of Maryland Center for Bioinformatics and Computational Biology (CBCB). "At first the tiny mutations were elusive. We thought we'd pieced together the 'jigsaw puzzle' of data very neatly, until we ended up with a few oddball bits left over. When we looked more closely, we found an extra copy of a critical gene."

"Fortunately, anthrax bacteria mutate relatively slowly, so the material in this colony developed these small distinctive mutations th
'/>"/>

Contact: Neil Tickner
ntickner@umd.edu
301-405-4622
University of Maryland
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Story tips from the US Department of Energys Oak Ridge National Laboratory March 2011
2. Genetic analysis reveals history, evolution of an ancient delicacy -- morels
3. Oldest fossils of large seaweeds, worm-like animals tell story of ancient oxygen
4. 3-D digital dinosaur track download: A roadmap for saving at-risk natural history resources
5. Story tips from the Department of Energys Oak Ridge National Laboratory January 2011
6. 2 books explore the history and delights of honey, bees and beehives
7. Portraits of the Mind author to present a visual history of the brain at public event in New York
8. Story tips from the Department of Energys Oak Ridge National Laboratory -- December 2010
9. Americas colonial hydrologic history recreated
10. Study rewrites the evolutionary history of C4 grasses
11. Darwins theory of gradual evolution not supported by geological history, NYU scientist concludes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/18/2015)... , June 18, 2015 This report analyzes ... by the following Product Segments, which includes Immunoassay Analyzers ... Immunoassay Systems, Radio Immunoassay Systems, and Nephelometric Immunoassay Systems. ... Canada , Japan ... , Latin America , and ...
(Date:6/17/2015)... , Deutschland und GERMANTOWN, Maryland , ... ®   Produktlinie mit DNA-Tests verbessert ... N.V. (NASDAQ: QGEN ; Frankfurt Prime Standard: QIA) ... neue STR-Testkits der Produktlinie Investigator ® ... den Markt eingeführt. Die neuen Kits zur Erstellung genetischer ...
(Date:6/17/2015)... , June 17, 2015  Synaptics Inc. (NASDAQ: ... solutions, today announced that Xiaomi, one of the ... ® ClearPad ® family of capacitive ... integrated circuits (DDICs) for its latest smartphones, the ... ClearPad for full in-cell display solutions and DDICs ...
Breaking Biology News(10 mins):Global Immunoassay Systems Market 2Global Immunoassay Systems Market 3Global Immunoassay Systems Market 4Global Immunoassay Systems Market 5Global Immunoassay Systems Market 6Global Immunoassay Systems Market 7Global Immunoassay Systems Market 8Global Immunoassay Systems Market 9Global Immunoassay Systems Market 10Global Immunoassay Systems Market 11Global Immunoassay Systems Market 12Global Immunoassay Systems Market 13Global Immunoassay Systems Market 14Global Immunoassay Systems Market 15Global Immunoassay Systems Market 16Global Immunoassay Systems Market 17Global Immunoassay Systems Market 18Global Immunoassay Systems Market 19Global Immunoassay Systems Market 20Global Immunoassay Systems Market 21Global Immunoassay Systems Market 22Global Immunoassay Systems Market 23Global Immunoassay Systems Market 24Global Immunoassay Systems Market 25Global Immunoassay Systems Market 26Global Immunoassay Systems Market 27Global Immunoassay Systems Market 28Global Immunoassay Systems Market 29QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 2QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 3QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 4QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 5QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 6Synaptics Touchscreen and Display Driver IC Solutions Power Xiaomi's Latest Flagship Smartphones 2Synaptics Touchscreen and Display Driver IC Solutions Power Xiaomi's Latest Flagship Smartphones 3
... centuries-old religious ceremony of an indigenous people in southern Mexico ... of fish, according to researchers from Texas A&M University. ... World, the Zoque people of southern Mexico would venture each ... Cueva del Azufre to implore their deities for a bountiful ...
... frequent intake of healthy foods such as fruit, vegetables, ... cheese and yoghurt compared with normal weight children. This ... University College, Norway and the Norwegian Institute of ... Overweight children drank juice and artificially ...
... Scientists have long known that large volcanic explosions ... solar energy and cool the air. Some suspect ... off dinosaurs and Neanderthals. In the summer ... far away as New England, and the 1991 blowout ...
Cached Biology News:Moved by religion: Mexican cavefish develop resistance to toxin 2Moved by religion: Mexican cavefish develop resistance to toxin 3Overweight children have different eating patterns than normal weight children 2Volcanic eruptions affect rainfall over Asian monsoon region 2Volcanic eruptions affect rainfall over Asian monsoon region 3
(Date:6/30/2015)... ... June 30, 2015 , ... Students and faculty from ... first half of “Integrative Biotechnology,” an applied biotechnology course team-taught by faculty members ... course combines students from both universities and is taught on both continents. , ...
(Date:6/30/2015)... WASHINGTON , June 30, 2015  NASA astronaut ... launch next month on his first mission to the ... interviews from 8 to 9 a.m. EDT Tuesday, July 7. ... Center in Star City, Russia . The ... on NASA Television highlighting his mission training. To ...
(Date:6/30/2015)... (PRWEB) , ... June 30, 2015 , ... ... , Study will provide new insights on mechanics of fecal microbiota transplantation in ... partnership to study the microbiome of patients undergoing fecal microbiota transplantation (FMT) as ...
(Date:6/30/2015)... ... June 30, 2015 , ... The maximum number of shares proposed to ... shares (including shares of unvested restricted stock). On June 29, 2015, the last trading ... Cryo-Cell’s shares reported on the OTCBB was $2.29 per share. , The tender offer ...
Breaking Biology Technology:Rivier University and Beijing City University Academic and Cultural Exchanges Begin 2NASA Astronaut Preps for First Space Station Mission, Available for Media Interviews 2uBiome and OpenBiome Partner for Microbiome Study in FMT Patients 2uBiome and OpenBiome Partner for Microbiome Study in FMT Patients 3Cryo-Cell Commences Tender Offer to Purchase its Common Stock, Up to 750,000 Shares at $3.25 per Share 2Cryo-Cell Commences Tender Offer to Purchase its Common Stock, Up to 750,000 Shares at $3.25 per Share 3
... Inc. (NYSE: AOB ) today announced its ... factors, $85 million aggregate,principal amount of Convertible Senior ... private placement exempt from the registration,requirements of the ... AOB currently expects to use approximately $30 ...
... the,product marketed by Bioelectronics Corp. (Pink Sheets: BIEL), is ... Recently chosen as "One of 9,Medical Breakthroughs That May ... treatment of choice for everything from soft,tissue injuries to ... the top 9 medical breakthroughs,was an easy one," said ...
... Senesco,Technologies, Inc. ("Senesco" or the "Company") (Amex: ... on the remaining $3.0 million of its,previously announced ... and Stanford Venture Capital Holdings, Inc. ("Stanford"). Senesco,has ... dependent $10 million,private placements of secured convertible debentures ...
Cached Biology Technology:American Oriental Bioengineering Proposes Offering of $85 Million of Convertible Notes 2American Oriental Bioengineering Proposes Offering of $85 Million of Convertible Notes 3BioElectronic's ActiPatch(TM) Product Chosen as 'One of 9 Medical Breakthroughs That May Change Your Life' 2BioElectronic's ActiPatch(TM) Product Chosen as 'One of 9 Medical Breakthroughs That May Change Your Life' 3BioElectronic's ActiPatch(TM) Product Chosen as 'One of 9 Medical Breakthroughs That May Change Your Life' 4Senesco Technologies Closes Remaining $3.0 Million of Previously Announced Financing 2Senesco Technologies Closes Remaining $3.0 Million of Previously Announced Financing 3
... contains sufficient materials for 1,464 array sample elements. , ... each , Blocker BSA in PBS (10X): 50 ... , BupH Phosphate Buffered Saline: 8 packs , ... West Pico Luminol Enhancer: 2 x 25 ml , ...
... counts cells based on specific fluorescence labelling ... so that other non cellular particles do ... 250 m square quartz cuvette each cell ... used as a counting signal and information ...
... Accurate Results Laser Capture Microdissection (LCM) ... and accuracy of molecular assays by starting ... multi-cellular structures isolated from whole tissue or ... in 1996 at the National Institutes of ...
Mouse monoclonal antibody raised against a partial recombinant DHX8. NCBI Entrez Gene ID = DHX8...
Biology Products: