Navigation Links
Novel nanotechnology heals abscesses caused by resistant staph bacteria
Date:12/22/2009

Investigative Dermatology, the interdisciplinary Einstein team showed that NO-containing nanoparticles could clear up superficial skin infections caused by MRSA. The current study of abscesses was designed to learn whether the nanoparticles could combat infections deep in the skin.

The researchers experimentally induced MRSA abscesses in 60 mice. The abscesses were either left untreated, topically treated with "empty" nanoparticles, or topically treated with nanoparticles containing NO and were evaluated four days later.

The microbial concentration in the abscesses of mice treated with NO-containing nanoparticles was significantly reduced compared with abscesses in the other two groups. In addition, the abscesses of mice treated with NO-containing nanoparticles had undergone much more healing, as shown by their improved appearance and by the far greater amounts of collagen (a protein important in maintaining the structure of skin) deposited within them.

The Einstein nanoparticle technology was developed by Joel M. Friedman, M.D., Ph.D., the Young Men's Division Chair of Physiology and professor of physiology & biophysics and of medicine, and Adam Friedman, M.D., currently the chief resident in the division of dermatology of the department of medicine at Montefiore Medical Center, The University Hospital and Academic Medical Center for Einstein.

When introduced on the skin or into the body, the tiny nanoparticles absorb water, swell up, and start releasing their cargo in a sustained manner. The nanoparticles can carry and release a variety of drugs as well as chemicals, including NO.

Produced naturally by cells throughout the body, NO has important biological properties including killing bacteria, healing wounds, and increasing blood flow by dilating blood vessels. "But NO is a very short-lived gas," notes Dr. Joel Friedman, "and, until now, methods to deliver it to targeted tissues in the proper doses have proven el
'/>"/>

Contact: Deirdre Branley
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. H1N1 influenza adopted novel strategy to move from birds to humans
2. Lupus Research Institute announces 2009 novel research grants
3. Novel NIST connector uses magnets for leak-free microfluidic devices
4. UD start-up company prepares to commercialize novel detector for medical, military applications
5. TAXIS Pharmaceuticals licenses novel antimicrobial technology from Rutgers and UMDNJ
6. Novel on-off switch mechanism stops cancer in its tracks
7. University of Miami receives NIH grant to support novel technology for tissue engineering
8. Novel bacterial strains clear algal toxins from drinking water
9. Novel genetic region identified for childhood asthma in Mexicans
10. Novel polymer could improve protein-based drugs
11. Novel mechanism revealed for increasing recombinant protein yield in tobacco
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Novel nanotechnology heals abscesses caused by resistant staph bacteria
(Date:1/22/2015)... man-made form of insulin delivered by nasal spray may ... with mild cognitive impairment and Alzheimer,s disease dementia, according ... Forest Baptist Medical Center. The study,s subjects ... (MCI) or mild to moderate Alzheimer,s dementia (AD). Those ...
(Date:1/22/2015)... 2015 , Europe,s ... The European Patent Office to present a video retrospective of the ... be featured: Christofer Toumazou and Sophie Wilson   ... winners of the Award   Starting on 22 January ...
(Date:12/24/2014)... , Dec. 23, 2014  Since its launch in December 2014, the ... eliminate the pain of trying to remember their usernames and ... fused to their smartphones. To assist people who have struggled ... company that created 1U and focuses on redefining identity, announced ...
Breaking Biology News(10 mins):Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 3Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 2Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 31U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3
... by the University of Colorado at Boulder and the ... liquid crystals of ultrashort DNA molecules immersed in water, ... the emergence of life on Earth. CU-Boulder ... surprisingly short segments of DNA, lifes molecular carrier of ...
... quack-quack there. Farmers may find phytochemicals to be the ... in the bucket that cashes in on the tug-o-war ... the Texas Agricultural Experiment Station. Thats because applying ... increases disease-preventing phytochemicals, or nutrients, for which consumers may ...
... in remote parts of the UK, southern Scandinavia and ... dissolved organic matter. In this weeks Nature journal (22 ... (University College London) and the US Environmental Protection Agency ... a return to a more natural, pre-industrial state following ...
Cached Biology News:Liquid crystal phases of tiny DNA molecules point up new scenario for first life on Earth 2Liquid crystal phases of tiny DNA molecules point up new scenario for first life on Earth 3Liquid crystal phases of tiny DNA molecules point up new scenario for first life on Earth 4Old McDonald had a phytochemical 2Old McDonald had a phytochemical 3Don't judge a brook by its color -- brown waters are more natural 2
(Date:1/22/2015)... RBJ today announces the firm brokered a long-term lease totaling ... biopharmaceutical company, at Two Ledgemont Center in Lexington, ... president, and Brian Cohen , senior vice president, represented ... 95 Hayden Ave. Photo - http://photos.prnewswire.com/prnh/20150122/170765 ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 The laboratory ... that has witnessed a number of technological advancements due ... regulatory requirements, growing need to integrate healthcare systems, and ... ease challenges in system integration. Key players in the ...
(Date:1/22/2015)... zFlo Motion , a US leader ... exciting product from a new partner. STT-Systems has ... past 15 years, with offerings in the optical-motion capture, 3D ... system (inertial measurement unit), iSen, is opening eyes around the ...
(Date:1/22/2015)... January 22, 2015 Diagenode, Inc., ... as the Bioruptor® and complete solutions for epigenetics ... chromatin immunoprecipitation, alleviating the need for manual processing. ... needed for ChIP of histones or transcription factors ...
Breaking Biology Technology:Transwestern | RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 3Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 43D Motion Capture Just Got Easy 2Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2
... Biotech Inc. (TSX: ONC, NASDAQ: ONCY ) ... Pandha of the Royal Surrey County Hospital, U.K., was ... Clinical Cancer Research. The paper is entitled "Synergistic Effects ... Melanoma." , The research demonstrated that the innate cancer ...
... , , RICHMOND, Va., Sept. ... fourth year in a row, according to an annual survey published ... brand follows recent No. 1 rankings from Pollina Corporate Real Estate ... rankings by all three of these reputable business brands at one ...
... , , ATLANTA, Sept. 24 ... (the "Company"), an Atlanta-based, biopharmaceutical company developing human vaccines for ... announcement today of partial success in the recently completed Phase ... by Sanofi-Aventis and Global Solutions for Infectious Diseases. The completed ...
Cached Biology Technology:Oncolytics Biotech(R) Inc. Announces Reovirus and Cisplatin Research Supports U.S. Phase 2 Metastatic Melanoma Trial 2Virginia Now Owns Three Top National Business Rankings 2Encouraging HIV/AIDS Vaccine Trial Results Support GeoVax Labs, Inc. Strategy 2Encouraging HIV/AIDS Vaccine Trial Results Support GeoVax Labs, Inc. Strategy 3Encouraging HIV/AIDS Vaccine Trial Results Support GeoVax Labs, Inc. Strategy 4
... Array Service enables scientists who have access to ... FAST Slides printed with proteins from S&Ss antibody ... the arrays is performed by the customer. Its ... discuss your needs with an expert and define ...
Acetylcholinesterase (human brain, AChE)...
... are used to study co-translational and ... events such as signal peptide cleavage, ... can be examined by the translation ... in the presence of these microsomal ...
Polio component type I...
Biology Products: