Navigation Links
Novel microscopy method offers sharper view of brain's neural network
Date:8/23/2012

neurons found in the cerebellum) and trace an entire brain's neuronal projections (the finger-like ends of a neuron by which neurochemical signals are received from other nerves).

According to Ludovico Silvestri, another member of the research team, this was the first time that a fluorescent mouse brain has been imaged in its entirety with such clarity. He adds that, in principle, the technique should be applicable to human brain samples if the current obstacle of fluorescently staining large blocks of fixed tissue can be overcome.

"The high-contrast fluorescence and fast acquisition assured by CLSM may represent a powerful tool to help neuroscientists navigate through the neuronal pathways of the brain," Pavone says. "Although this study was focused on brain imaging, we believe that CLSM also is ideally suited to exploreat micron-scale resolutionthe anatomy of different specimens such as murine organs, embryos and flies."

Along with refining CLSM to improve its imaging capabilities, Silvestri says the research team is using CLSM to image mouse models of several diseases, including autism and ischemic stroke. "We hope that the whole-brain tomographies we can obtain will one day provide insights into the mechanisms of these and other brain disorders," he says.


'/>"/>
Contact: Angela Stark
astark@osa.org
202-416-1443
Optical Society of America
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Novel nano-structures to realize hydrogens energy potential
2. Cleveland Clinic researchers receive $5 million grant to discover novel pathways to heart disease
3. VTT and GE Healthcare developing novel biomarkers to predict Alzheimers disease
4. Mexican rock heroes trial novel green trading system
5. London researchers discover novel mechanism involved in key immune response
6. Novel discovery by NUS scientists paves the way for more effective treatment of cancers
7. Key proteins newly discovered form and function may provide novel cancer treatment target
8. Unique adaptations to a symbiotic lifestyle reveal novel targets for aphid insecticides
9. Notre Dame researchers using novel method to combat malaria drug resistance
10. New clinical trial explores novel noninvasive colon cancer screening test
11. Researchers discover novel therapy for Crohns disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Novel microscopy method offers sharper view of brain's neural network
(Date:8/5/2015)... -- According to a new market research ... Vertical (BFSI, Airport, IT & Telecom, Utilities, Education, Defense ... 2020", published by MarketsandMarkets, defines and segments the Physical ... The global PIAM Market is estimated to grow from ... at a CAGR of 14.9 % from 2014 to ...
(Date:8/4/2015)... 2015 Research ... the addition of the "Digital Forensics ... Sub-Segment (Computer Forensics, Network Forensics, Mobile Device ... Vertical and Region - Global Forecast to ... By Component (Hardware, Software, and Service), ...
(Date:7/31/2015)... , Kina, 31. juli 2015 Den ... bliver afholdt af BGI fra den 22. - 25. oktober ... Konferencen fejrer sin 10-års fødselsdag i år. Siden ... mest indflydelsesrige årlige møder på ,omik,-feltet, og er en ... ICG-10 fokuserer på nylige gennembrud og ...
Breaking Biology News(10 mins):Physical Identity and Access Management Market Worth $546.2 Million by 2019 2Physical Identity and Access Management Market Worth $546.2 Million by 2019 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 4Digital Forensics Market - The Market Represents a Compound Annual Growth Rate (CAGR) of 11.3% From 2015 to 2020 2Den 10. internationale konference om Genomics (ICG-10) åbner i oktober 2
... hundreds, if not thousands, of suspected toxic substances every ... the brain, immune system, reproductive organs or hormones. Children ... requires product testing of most chemical compounds before they ... Riverside professor Carl Cranor argues in a new book, ...
... research effort designed to prevent the introduction of viruses to ... Chesapeake Bay watermen improve their bottom line by reducing the ... The findings, published in the journal Diseases of Aquatic ... in diseased and dying crabs likely occurs after the pre-molt ...
... scientists of the Technische Universitaet Muenchen (TUM) have been ... Prof. Stephan A. Sieber for the development of drugs ... million to study interactions between cellular components; 1.6 million ... a basic theory on elementary particles; Prof. Daniel Cremers ...
Cached Biology News:Legally poisoned 2Blue crab research may help Chesapeake Bay watermen improve soft shell harvest 2Nearly 10 million euros ($13.6 million) in ERC grants for 6 Technische Universitaet Muenchen researchers 2Nearly 10 million euros ($13.6 million) in ERC grants for 6 Technische Universitaet Muenchen researchers 3Nearly 10 million euros ($13.6 million) in ERC grants for 6 Technische Universitaet Muenchen researchers 4Nearly 10 million euros ($13.6 million) in ERC grants for 6 Technische Universitaet Muenchen researchers 5Nearly 10 million euros ($13.6 million) in ERC grants for 6 Technische Universitaet Muenchen researchers 6
(Date:8/28/2015)... ... August 28, 2015 , ... ... orthopedic surgeon, Wade McKenna, DO, announced today that the use of sterile, dehydrated ... in complete healing of an otherwise non-healing surgical knee wound. , The case ...
(Date:8/27/2015)... 27, 2015 /PRNewswire/ - Portage Biotech Inc. ("Portage") ... Biohaven Pharmaceutical Holding Company Limited (Biohaven), announced today ... study of BHV-0223, a glutamate modulating agent. Biohaven ... and recently obtained clearance from the U.S. Food ... testing. Portage holds 54% equity interest in Biohaven, ...
(Date:8/27/2015)... , August 27, 2015 GlassesOff (OTCBB: ... processing functions in the human vision system, announced today a ... point guard Chris Paul to develop a new ... want to improve their real-life on-court performance. Vision ... whether it is shooting a ball or blocking a pass. ...
(Date:8/26/2015)... ... August 26, 2015 , ... ... that a second US laboratory is to open in Manhattan, Kansas in early ... partnership and long-term growth of research and development through collaboration with researchers from ...
Breaking Biology Technology:Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 2Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 3Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 4Portage's Biohaven doses first human subject in Phase 1 trial with lead drug candidate BHV-0223 2Portage's Biohaven doses first human subject in Phase 1 trial with lead drug candidate BHV-0223 3Portage's Biohaven doses first human subject in Phase 1 trial with lead drug candidate BHV-0223 4Eight-Time All-Star Chris Paul and GlassesOff Partner to Develop Innovative Mobile App Designed to Improve On-Court Performance 2Eight-Time All-Star Chris Paul and GlassesOff Partner to Develop Innovative Mobile App Designed to Improve On-Court Performance 3MediVet Biologics Animal Health Secures Additional Laboratory Facility in Manhattan, Kansas 2MediVet Biologics Animal Health Secures Additional Laboratory Facility in Manhattan, Kansas 3
... flowers: in the nineties of the last century Norwegian ... in petunias inhibited its activity instead of reinforcing it ... was found that the mechanism is based on the ... the late nineties the Nobel prizewinners Andrew Fire and ...
... deal with the same problems, but they use different ... be difficult, if not impossible., A new $2.9 million ... National Science Foundation (NSF), will help bridge this problematic ... common problems a range of scientists face., The grant ...
... Quest Diagnostics,Incorporated (NYSE: DGX ), the nation,s leading ... is scheduled to speak,at the 2007 UBS Global Life ... 2007. The Quest Diagnostics presentation is scheduled to,begin at ... webcast live during the conference and will be,available to ...
Cached Biology Technology:Mechanism for the in-vivo transport of siRNA 2Mechanism for the in-vivo transport of siRNA 3CCMR gets $2.9M for training grad students in nanoscale science 2Quest Diagnostics to Speak at the 2007 UBS Global Life Sciences Conference 2
Anti-DAP-1, Rabbit Monoclonal Immunogen: KLH-conjugated synthetic peptide corresponding to the C-terminal region of human DAP-1. Molecular Weight: 11 kDa Quality Assurance: Routinely eval...
Mouse monoclonal [TONI-1] to Angiotensin II Type 1 Receptor (rating: ****) ( Abpromise for all tested applications). entrezGeneID: 185 SwissProtID: P30556...
1/4" to 1/8" Adapter for Reflectance Probe Holder...
... (GLP-1), C-terminal reactive. Cross-reacts fully with ... reactivity with the unamidated forms GLP-1(7-37) ... such as hGLP-2, glucagon, hGIP and ... is identical in all mammalian species ...
Biology Products: