Navigation Links
Novel microscopy method offers sharper view of brain's neural network
Date:8/23/2012

neurons found in the cerebellum) and trace an entire brain's neuronal projections (the finger-like ends of a neuron by which neurochemical signals are received from other nerves).

According to Ludovico Silvestri, another member of the research team, this was the first time that a fluorescent mouse brain has been imaged in its entirety with such clarity. He adds that, in principle, the technique should be applicable to human brain samples if the current obstacle of fluorescently staining large blocks of fixed tissue can be overcome.

"The high-contrast fluorescence and fast acquisition assured by CLSM may represent a powerful tool to help neuroscientists navigate through the neuronal pathways of the brain," Pavone says. "Although this study was focused on brain imaging, we believe that CLSM also is ideally suited to exploreat micron-scale resolutionthe anatomy of different specimens such as murine organs, embryos and flies."

Along with refining CLSM to improve its imaging capabilities, Silvestri says the research team is using CLSM to image mouse models of several diseases, including autism and ischemic stroke. "We hope that the whole-brain tomographies we can obtain will one day provide insights into the mechanisms of these and other brain disorders," he says.


'/>"/>
Contact: Angela Stark
astark@osa.org
202-416-1443
Optical Society of America
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Novel nano-structures to realize hydrogens energy potential
2. Cleveland Clinic researchers receive $5 million grant to discover novel pathways to heart disease
3. VTT and GE Healthcare developing novel biomarkers to predict Alzheimers disease
4. Mexican rock heroes trial novel green trading system
5. London researchers discover novel mechanism involved in key immune response
6. Novel discovery by NUS scientists paves the way for more effective treatment of cancers
7. Key proteins newly discovered form and function may provide novel cancer treatment target
8. Unique adaptations to a symbiotic lifestyle reveal novel targets for aphid insecticides
9. Notre Dame researchers using novel method to combat malaria drug resistance
10. New clinical trial explores novel noninvasive colon cancer screening test
11. Researchers discover novel therapy for Crohns disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Novel microscopy method offers sharper view of brain's neural network
(Date:8/27/2014)... pathogens posing the greatest risk to Europe based upon ... of Liverpool researchers using a ,big data, approach to ... of Infection and Global Health ranked the top 100 ... animals using a system which, they believe, will help ... the spread of infectious diseases, including as a result ...
(Date:8/27/2014)... news release is available in German . ... 1A is the most common inherited disease affecting the ... at the Max Planck Institute of Experimental Medicine and ... of Schwann cells is impaired in rats with the ... insulating layer known as myelin, which facilitates the rapid ...
(Date:8/27/2014)... Outstanding basic research, a growing focus on ... patient care have earned the Herbert Irving Comprehensive ... (CUMC) and NewYork-Presbyterian Hospital an $18 million, five-year ... Institute (NCI). The grant renews the center,s status ... Centers in New York City and one of ...
Breaking Biology News(10 mins):Big data approach identifies Europe's most dangerous human and domestic animal pathogens 2Potential therapy for incurable Charcot-Marie-Tooth disease 2Herbert Irving Comprehensive Cancer Center awarded $18 million grant 2Herbert Irving Comprehensive Cancer Center awarded $18 million grant 3Herbert Irving Comprehensive Cancer Center awarded $18 million grant 4
... Off Hachinohe, JapanScientific deep sea drilling vessel Chikyu sets ... rock samples from deeper than 2,111 meters below the ... Pacific Ocean. The Japan Agency for Marine-Earth Science and ... the Chikyu, announced this achievement on 6th September, 2012. ...
... in 150 (84%) European crops. These crops depend partly ... The value of insect pollinators is estimated to be ... pollinators, such as honeybees, and wild pollinator such bumblebees, ... as we need to protect food production and the ...
... 1 percent of the human genome contains gene regions that ... of the DNA is doing. Scientists have now begun to ... biochemically active, and likely involved in regulating the expression of ... team of researchers. The consortium, known as ENCODE (which ...
Cached Biology News:Chikyu sets a new world drilling-depth record of scientific ocean drilling 2Wild bees: Champions for food security and protecting our biodiversity 2Wild bees: Champions for food security and protecting our biodiversity 3Researchers identify biochemical functions for most of the human genome 2Researchers identify biochemical functions for most of the human genome 3
(Date:8/27/2014)... TX (PRWEB) August 27, 2014 The ... and in-depth study on the current state of the ... report provides a basic overview of the industry, including ... and Chinese domestic market analysis are provided with a ... the market. A comparison between the international and Chinese ...
(Date:8/27/2014)... MADISON, N.J. , Aug. 27, 2014 /PRNewswire/ ... significant potential to help physicians better identify early-stage ... progression and disability, according to a new study ... from Quest Diagnostics (NYSE: DGX ) ... of the 14-3-3eta protein outperformed conventional antibody-serum testing, ...
(Date:8/27/2014)... 27, 2014 Flagship Biosciences LLC, a ... to the pharmaceutical and medical device industries, has announced ... fast growing company has consolidated its histology and tissue ... to Westminster, CO, just north of Denver. The ... W. 103rd Ave., Suite 100, Westminster, CO 80021 , ...
(Date:8/27/2014)... , Aug. 27, 2014 Tris Pharma, a ... technologies, today announced that it has been selected as ... Industry Association,s 2014 Awards for Excellence competition ... an independent panel of judges from SCORE (Counselors to ... winners will be honored at a gala event to ...
Breaking Biology Technology:Trifluoroacetic Acid Industry (Asia, Europe, North America, ROW) Analysis Report Now Available at ReportsnReports.com 2Novel Biomarker Detects Early Rheumatoid Arthritis Better than Conventional Methods Alone, According to Journal of Rheumatology Study 2Novel Biomarker Detects Early Rheumatoid Arthritis Better than Conventional Methods Alone, According to Journal of Rheumatology Study 3Novel Biomarker Detects Early Rheumatoid Arthritis Better than Conventional Methods Alone, According to Journal of Rheumatology Study 4Flagship Biosciences Announces Relocation and Expansion 2Tris Pharma Selected as an award winner in the New Jersey Business & Industry Association's 2014 Awards for Excellence 2
... Medivation, Inc.,(Nasdaq: MDVN ) today reported on its ... 31, 2007., "In 2007 we continued our track ... portfolio, and we are pleased to,enter 2008 with an ... David T. Hung, M.D., president and chief,executive officer of ...
... a way to, protect the lives of the nation,s firefighters ... ... IRVINE, Calif., Feb. 19 Masimo (Nasdaq:,MASI), the inventor of Pulse ... National Fire Protection,Association (NFPA) has included Carbon Monoxide (CO) screening by Pulse,CO-Oximetry ...
... Onyx,Pharmaceuticals, Inc. (Nasdaq: ONXX ) today announced that ... update on Nexavar(R),(sorafenib) tablets, as well as to discuss ... February 19, 2008, at 10:00 a.m.,Eastern Time (7:00 a.m. ... ended December 31, 2007 will be released today., ...
Cached Biology Technology:Medivation Reports Year-End 2007 Financial Results and Pipeline Progress 2Medivation Reports Year-End 2007 Financial Results and Pipeline Progress 3Medivation Reports Year-End 2007 Financial Results and Pipeline Progress 4Medivation Reports Year-End 2007 Financial Results and Pipeline Progress 5Medivation Reports Year-End 2007 Financial Results and Pipeline Progress 6Medivation Reports Year-End 2007 Financial Results and Pipeline Progress 7National Fire Protection Association (NFPA) Sets New National Standard for CO Screening by Pulse CO-Oximetry(TM) 2National Fire Protection Association (NFPA) Sets New National Standard for CO Screening by Pulse CO-Oximetry(TM) 3National Fire Protection Association (NFPA) Sets New National Standard for CO Screening by Pulse CO-Oximetry(TM) 4Onyx Pharmaceuticals Announces a Teleconference and Webcast to Provide an Update on Nexavar and Report Full Year 2007 Financial Results 2
... is the industry standard microarray image analysis ... imaging and analysis tools, visualizations, automation capabilities, ... is included with every GenePix scanner, and ... scanners and all types of arrays. A ...
... is the ideal instrument for budget-conscious labs that ... applications. Get Applied Biosystems proven PCR ... lab space without sacrificing results. Enhance ... Technology You Can Afford The Applied ...
... synthesis with a wide variety of purity levels, ... needs. Purity: IG(>50%), >70%, >80% ... Sequence Length: Up to 120 residues ... phosphorylation, D-amino acids, MAPs, KLH/BSA conjugation, and much ...
... The AquaMax DW4 liquid handling system from ... washing all in one instrument. The system ... dispensing and plate washing96-, 384- and 1536-welland ... washing. AquaMax DW4 has been optimized to ...
Biology Products: