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Novel discovery by NUS scientists paves the way for more effective treatment of cancers
Date:5/21/2012

toxic. This raises the hope of offering a new dual-drug cancer treatment regime for cancers such as lymphoma, prostate, glioblastoma, breast and kidney cancer cells that is more effective and with fewer side-effects.

The Next Step

Armed with structural insights into the binding and signaling pathway that activates glutaminase, the NUS research team is conducting more studies to determine whether a combination of drugs would be even more effective in inhibiting glutaminase activity and hence, tumour formation.

Using the knowledge that they gained through their current studies, the research team will also look into optimising the tumour suppression property of BPTES to increase its efficiency and lower its side-effects.


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Contact: Carolyn Fong
carolyn@nus.edu.sg
65-651-65399
National University of Singapore
Source:Eurekalert

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