Navigation Links
Novel bioreactor enhances interleukin-12 production in genetically modified tobacco plants
Date:12/5/2008

om those modified tobacco plants were then grown in a mist reactor developed in the Weathers lab. As its name implies, the mist reactor uses ultrasonic technology to spray a fine mist of water and nutrients on the root cultures, which are suspended in a plastic bag. The nutrient solution is collected at the bottom of the bag and recycled through the system. In this way, all of the materials are completely contained and isolated from the environment.

"Some have concerns about growing genetically modified plants in an open field where they could cross-pollinate with other species. Our mist reactor overcomes those concerns because the system is completely contained," Weathers says. "There is no interaction with the environment, and once we've collected the therapeutic proteins grown in the roots, all the remaining material is safely destroyed."

Traditional pharmaceuticals, like aspirin or statins for lowering cholesterol, are made by synthesizing and combining chemicals in a factory-like production setting. Therapeutic proteins are biologic molecules produced in living cells, which are then isolated, purified and prepared for use in treating disease. For example, insulin is a therapeutic protein now produced by inserting a human insulin gene into bacteria, which in turn prompts the bacteria to make human insulin. Using plants as a production system for therapeutic proteins can not only be more cost-effective than animal cell-based production, but can also significantly reduce the risk of contamination by animal or human viruses or pathogens.

In the current study, Weathers compared the capabilities of the mist reactor with two other common methods for growing plant culturesthe shake flask method and the airlift bioreactor. The results showed the mist reactor produced the highest concentration of interleukin 12. "Our system is simple and scalable. We'll use these data to optimize this kind of process and scale it up to the next level," Weath
'/>"/>

Contact: Michael Cohen
mcohen@wpi.edu
508-868-4778
Worcester Polytechnic Institute
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Stowers Institutes Workman Lab discovers novel histone demethylase protein complex
2. A little wine boosts omega-3 in the body: Researchers find a novel mechanism for a healthier heart
3. A novel target for therapeutics against Staph infection
4. Corn researchers discover novel gene shut-off mechanisms
5. 3-substituted indolones as novel therapeutic compounds for neurodegenerative conditions
6. UT Southwestern researcher awarded Gates Foundation grant for novel vaccine development
7. GEN reports on novel tools for deciphering biological networks
8. Novel publishing approach puts textbook in more hands
9. Cold Spring Harbor Laboratory scientists trace a novel way cells are disrupted in cancer
10. Childrens National researchers develop novel anti-tumor vaccine
11. LIAI launches new division to look at novel approaches to heart disease and inflammation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... , Jul. 31, 2015 NXT-ID, Inc. (NASDAQ: ... company focused on the growing mobile commerce market and ... has filed provisional patent 62/198989 for ELECTRONIC ... highlights a method to advance crypto-currencies such as Bitcoin ... a common, uniform way to manage all payments.  ...
(Date:7/23/2015)... (NASDAQ: AWRE ), a leading supplier of biometrics software ... ended June 30, 2015.  Revenue for the ... 33% compared to $6.8 million in the same quarter last ... $0.3 million, or $0.01 per diluted share, which compared to ... period a year ago.  Lower revenue and ...
(Date:7/20/2015)...  Acuity Market Intelligence,s latest research "The Global ... and Privacy" forecasts that between 2014 and 2020 ... downloaded to smart mobile devices by 2.2 billion ... projected to generate more than $67.9 billion in ... period.    "Biometrics is at the ...
Breaking Biology News(10 mins):NXT-ID Patents Electronic Crypto-Currency Management Technology 2NXT-ID Patents Electronic Crypto-Currency Management Technology 3NXT-ID Patents Electronic Crypto-Currency Management Technology 4Aware, Inc. Reports Second Quarter 2015 Financial Results 2Aware, Inc. Reports Second Quarter 2015 Financial Results 3Aware, Inc. Reports Second Quarter 2015 Financial Results 4Aware, Inc. Reports Second Quarter 2015 Financial Results 5Aware, Inc. Reports Second Quarter 2015 Financial Results 6Biometrics on Smart Mobile Devices to Redefine Digital Identity with 12.9 Billion Biometric App Downloads between 2014 and 2020 2
... the complex biological systems found at the sub-cellular ... the academic fields of biology and physics. However, ... of exciting advances in super-resolution imaging technologies. ... OShea, a biophysicist at the University of Nottingham, ...
... constantly exchanging materials through the movement of air ... rivers and the migration of animals across the ... another major driver of connectivity among ecosystems. In ... Ecology and the Environment, titled Continental-scale ecology in ...
... 30 Platinum Solutions, Inc. announced,it is part ... selected by the,Federal Bureau of Investigation to develop ... Division,s Next Generation,Identification (NGI) Program, an enhanced identification ... of the winning Lockheed Martin team, Platinum,Solutions will ...
Cached Biology News:Synergy between biology and physics drives cell-imaging technology 2Ecological globalization 2Platinum Solutions, Inc. Teams with Lockheed Martin on Federal Bureau of Investigation's Next Generation Identification Program 2
(Date:7/30/2015)... (PRWEB) , ... July 30, 2015 , ... ... has appointed Francois Vieillard as Sales & Marketing Director. , With more ... Vieillard will be responsible for reinforcing Tronics’ business development activities worldwide. He brings ...
(Date:7/30/2015)... , Inc. (NASDAQ: SNMX ), a leading company ... commercialize novel flavor ingredients for the food, beverage, and ... second quarter 2015. "Moving into the ... achieve our commercial and financial goals," stated John Poyhonen, ... our last quarterly earnings report, our two partners have ...
(Date:7/30/2015)... NY (PRWEB) , ... July 30, 2015 , ... As part of its 2015 growth ... material and technical service business units, Whitehouse Laboratories is pleased to announce ... be adjacent to the Container Center of Excellence and will be strictly dedicated to basic ...
(Date:7/29/2015)... 2015 US-Australian drug discovery company, Novogen Limited ... is committed to progressing its ground-breaking technology platforms to ... to ensure the Company delivers the best value for ... Ross , said the Company currently had an extensive ... discovery programs and academic partnerships and initiatives, and he ...
Breaking Biology Technology:Tronics appoints Francois Vieillard as Sales and Marketing Director 2SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 2SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 3SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 4SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 5SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 6SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 7SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 8SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 9Whitehouse Labs Formally Announces Plans to Open a Microbiological Laboratory 2Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 2Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 3Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 4Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 5Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 6Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 7Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 8Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 9Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 10
... at 7:10 p.m. Eastern Time TodayBOTHELL, WA, and VANCOUVER, ... OGXI ) today announced the final results of ... presentation at the American Society of Clinical Oncology (ASCO) ... treated with OGX-011 in combination with docetaxel compared to ...
... and refractive eye surgery experts listed at Trusted LASIK ... recent American Society of Cataract and Refractive Surgery (ASCRS) ... Majmudar, Dr. Shachar Tauber, and Dr. William Trattler were ... Cup. The Challenge Cup is a competition between ...
... Brand collaborate with Seahorse Bioscience, Inc. to organize ... their years of experience studying promising disease pathways ... Seahorse Bioscience, Inc., the market leader in instruments ... their first Cellular Bioenergetics Workshop, " Understanding ...
Cached Biology Technology:OncoGenex Pharmaceuticals Announces OGX-011 Treatment Provides Survival Benefit in Randomized Phase 2 Trial in Advanced Metastatic Prostate Cancer 2OncoGenex Pharmaceuticals Announces OGX-011 Treatment Provides Survival Benefit in Randomized Phase 2 Trial in Advanced Metastatic Prostate Cancer 3OncoGenex Pharmaceuticals Announces OGX-011 Treatment Provides Survival Benefit in Randomized Phase 2 Trial in Advanced Metastatic Prostate Cancer 4OncoGenex Pharmaceuticals Announces OGX-011 Treatment Provides Survival Benefit in Randomized Phase 2 Trial in Advanced Metastatic Prostate Cancer 5OncoGenex Pharmaceuticals Announces OGX-011 Treatment Provides Survival Benefit in Randomized Phase 2 Trial in Advanced Metastatic Prostate Cancer 6OncoGenex Pharmaceuticals Announces OGX-011 Treatment Provides Survival Benefit in Randomized Phase 2 Trial in Advanced Metastatic Prostate Cancer 7OncoGenex Pharmaceuticals Announces OGX-011 Treatment Provides Survival Benefit in Randomized Phase 2 Trial in Advanced Metastatic Prostate Cancer 8LASIK and Vision Correction Experts from Trusted LASIK Surgeons Directory Achieve Top Awards at ASCRS Meeting 2LASIK and Vision Correction Experts from Trusted LASIK Surgeons Directory Achieve Top Awards at ASCRS Meeting 3LASIK and Vision Correction Experts from Trusted LASIK Surgeons Directory Achieve Top Awards at ASCRS Meeting 4LASIK and Vision Correction Experts from Trusted LASIK Surgeons Directory Achieve Top Awards at ASCRS Meeting 5LASIK and Vision Correction Experts from Trusted LASIK Surgeons Directory Achieve Top Awards at ASCRS Meeting 6LASIK and Vision Correction Experts from Trusted LASIK Surgeons Directory Achieve Top Awards at ASCRS Meeting 7New Cellular Bioenergetics Workshops Series Inaugurated by Seahorse Bioscience with Two of the World's Leading Bioenergetics Researchers 2New Cellular Bioenergetics Workshops Series Inaugurated by Seahorse Bioscience with Two of the World's Leading Bioenergetics Researchers 3
G-Protein Coupled Receptor Assay, For 500 assays. SPA. Category: Drug Screening & Cellular Assays, Assays ....
EDTA, disodium salt, 1 kg. Ethylene diaminetetraacetic acid.Dihydrate. Assay: 99.0-101.0%, nuclease-free.Risks: 36, 37, 38 ; Safety Precautions: 22, 36, 37. Category: Nucleotides & Enzymes & Biochemi...
Alkaline Phosphatase Stabilizer Solution, 1 L...
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5...
Biology Products: