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Novel bioactive peptides promote wound healing in vivo
Date:2/24/2012

peptides could act synergistically to improve human wound healing moves our research one significant step closer to clinical application. We hope that someday soon, we may be able to help transform the way in which wound care is being delivered in civilian and combat settings," said Ira Herman, PhD, professor of molecular physiology and pharmacology at Tufts University School of Medicine. Professor Herman is director, molecular and cellular physiology graduate program at the Sackler School of Graduate Biomedical Sciences and director, Center for Innovations in Wound Healing Research, Tufts University.

"The wound-healing peptides should also prove strategic as we continue developing 'smart' devices or fully-vascularized living tissue constructs for burn patients or those patients suffering with diabetic plantar or venous stasis ulcers. Clinical trials using the peptides will be the next step," Herman continued. Tufts University has filed patent applications related to the wound-healing peptides.

Tufts Center for Innovations in Wound Healing Research brings together experts from Tufts' medical, dental, veterinary and engineering schools, as well as Tufts Medical Center and local research institutes with a focus on creating innovative wound healing therapeutics as well as fully-vascularized organ constructs for personalized regenerative medicine.

Demidova-Rice is now at the Edwin L. Steele Laboratory for Tumor Biology in the department of Radiation Oncology at Massachusetts General Hospital. Additional authors include Lindsey Wolf, BS, formerly a research assistant at TUSM, now a graduate student working towards a PhD degree in the department of molecular genetics and microbiology at the University of Texas at Austin; Jeffry Deckenback, PhD, who was a postdoctoral fellow in the Herman lab while the work was being carried out; and Michael R. Hamblin, PhD, a principal investigator at the Wellman Center for Photomedicine at Massachusetts Gene
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Contact: Siobhan E. Gallagher
siobhan.gallagher@tufts.edu
617-636-6586
Tufts University, Health Sciences Campus
Source:Eurekalert

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