Navigation Links
Novel aspects of histamine research discussed in Versita open access book
Date:11/13/2013

Histamine H4 Receptors: A novel Drug Target for Immunomodulation and Inflammation, edited by Professor Holger Stark, is a new Open Access Book comprising key results from the highly acclaimed Action BM0806, held by COST (European Cooperation in Science and Technology), which was instituted to champion and promote a multidisciplinary approach to H4R research, and focused on the current state of play pertaining to the basic understanding and the huge therapeutic potential of this new drug target. The objective of this project was to advance awareness of the newly identified histamine receptor.

The book describes molecular signaling mechanism, the function as well as the localization of this receptor subtype, along with its influence on physiological and pathophysiological properties. It offers an insight into a range of perspectives on H4R research, and a thorough analysis of the possibilities for novel therapeutic inventions and exploitation, allowing for newly designed compounds as well as numerous biochemical in vitro and in vivo models on different species.

Chapter by chapter, different aspects of histamine research are presented and discussed. The contributing authors were all active members of Action BM0806 and as a result, the book covers the most original and topical aspects of histamine research. One of them is the role of histamine in allergic reactions, which was assumed to have been clarified for many decades. Presently, the increased understanding of histamine and its functions places it at the centre stage in the orchestration of the innate immune response and lead-up to the adaptive response. Professor Madeleine Ennis (Secretary, COST Action BM0806) and colleagues discuss in detail the evidence for the roles of various histamine receptors (particularly the H4R) in immune cell function, spanning eosinophils, monocytes, basophils, mast cells and neutrophils. Another newsworthy section, dedicated to histamine and cancer, is written by one of the leading specialists in the field Professor Elena S. Rivera, a global expert on histamine and cell proliferation, who provides exciting new data that supports the H4R as a novel target for a range of refractory cancers. Finally, the closing chapter discusses the non-receptor role of histamine a fascinating topic, albeit so far largely under-studied by the histamine community.

Considering its cross-sectional approach, the book will benefit not only societies and professional organizations, but all scientists involved in biogenic amine research and those with special emphasis on histamine research should find it an invaluable read. As Dr. Paul L Chazot, President of European Histamine Research Society points out: "This new Book offers something for everyone across disciplines, and individuals with either a deep or passing interest in histamine will be kept entertained and informed."


'/>"/>

Contact: Maria Hrynkiewicz
maria@versita.com
48-660-476-421
Versita
Source:Eurekalert  

Related biology news :

1. Novel LEDs pave the way to cheaper displays
2. Novel technique for suturing tissue-engineered collagen graft improves tendon repair
3. Novel mutations define 2 types of bone tumor
4. NIH funds development of novel robots to assist people with disabilities, aid doctors
5. Mutations in novel tumor suppressor gene associated with early onset breast cancer
6. IRICoR and Université de Montréal license a novel program for early-onset morbid obesity to Pfizer
7. Novelty of eco-friendly bamboo garments lures consumers -- if the price is right, Baylor study shows
8. Novel mechanism discovered in first line of immune defense
9. Novel avian influenza A virus has potential for both virulence and transmissibility in humans
10. Researchers develop novel polymer to help oral medications reach the bloodstream
11. Novel approach to gene regulation can activate multiple genes simultaneously
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Novel aspects of histamine research discussed in Versita open access book
(Date:4/28/2016)... FRANCISCO and BANGALORE, India , ... of EdgeVerve Systems, a product subsidiary of Infosys (NYSE: ... provider, today announced a global partnership that will ... way to use mobile banking and payment services. ... is a key innovation area for financial services, but it ...
(Date:4/15/2016)... April 15, 2016  A new partnership announced ... accurate underwriting decisions in a fraction of the ... priced and high-value life insurance policies to consumers ... With Force Diagnostics, rapid testing (A1C, Cotinine ... readings (blood pressure, weight, pulse, BMI, and activity ...
(Date:3/31/2016)... 2016  Genomics firm Nabsys has completed a financial ... Bready , M.D., who returned to the company in ... leadership team, including Chief Technology Officer, John Oliver ... Nurnberg and Vice President of Software and Informatics, ... Dr. Bready served as CEO of Nabsys from ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... NC (PRWEB) , ... June 27, 2016 , ... ... just published their findings on what they believe could be a new and ... of the new research. Click here to read it now. , ...
(Date:6/27/2016)... N.C. (PRWEB) , ... June 27, 2016 , ... ... commercial operations for Amgen, will join the faculty of the University of ... as adjunct professor of strategy and entrepreneurship at UNC Kenan-Flagler, with a focus ...
(Date:6/24/2016)... , June 24, 2016  Regular discussions on a ... take place between the two entities said Poloz. ... Ottawa , he pointed to the country,s ... the federal government. ... said, "Both institutions have common economic goals, why not sit ...
(Date:6/24/2016)... ... ... Researchers at the Universita Politecnica delle Marche in Ancona combed medical journal ... Their findings are the subject of a new article on the Surviving Mesothelioma website. ... the blood, lung fluid or tissue of mesothelioma patients that can help point doctors ...
Breaking Biology Technology: