Navigation Links
Novel 'antisense' therapies protect primates from lethal Ebola and Marburg viruses
Date:8/22/2010

cidentally, earlier that very day, Dr. Patrick Iversen from AVI BioPharma had presented a seminar at USAMRIID concerning the efficacy of novel antisense drugs against a range of viruses. When he found out that a USAMRIID scientist had potentially been exposed to Ebola virus, the company volunteered to design and synthesize compounds against the virus to treat her if the need arose.

The team at AVI worked for four straight days to generate human-grade anti-Ebola compounds. In the meantime, their regulatory staff worked with USAMRIID physicians to gain emergency approval from the U.S. Food and Drug Administration to use the compounds if necessary. Five days after the exposure, AVI delivered the compounds to USAMRIID's medical team.

Fortunately, the scientist had escaped infection with Ebola virus, so the compounds were never used. However, USAMRIID went on to test them in animal models, and has been collaborating with AVI ever since.

According to the authors, the investigational new drug applications (IND) for AVI-6002 and AVI-6003 have been submitted to the U.S. Food and Drug Administration, and they are now open to proceed with clinical trials.


'/>"/>

Contact: Caree Vander Linden
caree.vander-linden@amedd.army.mil
US Army Medical Research Institute of Infectious Diseases
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related biology news :

1. Novel bee venom derivative forms a nanoparticle smart bomb to target cancer cells
2. UM researcher identifies novel treatment for pain in sickle cell disease
3. Novel microfluidic HIV test is quick and cheap
4. NIH-supported study finds novel pathway may open doors for new blood pressure treatments
5. Novel protein essential for successful pregnancy
6. UT Southwestern researchers use novel sperm stem-cell technique to produce genetically modified rats
7. Novel processing technologies developed for extending use of oats in gluten-free diet
8. Novel strategy for generating induced pluripotent stem cells for clinical use is safe and efficient
9. International research team discovers novel genes influencing kidney disease risk
10. Researchers use novel nanoparticle vaccine to cure type 1 diabetes in mice
11. Pitt-led international study identifies human enzyme that breaks down potentially toxic nanomaterials, opens door to novel drug delivery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2013)... "place" is increasingly being considered in the management ... new resource that can help them recognize and ... places in their lives. , Place-Based Conservation: ... co-edited by the Pacific Northwest Research Station,s Linda ... to conservation. The book is published by Springer ...
(Date:5/21/2013)... types become most deadly when they metastasize and spread ... stage, it becomes very difficult for doctors to locate ... researchers at the University of Missouri have found a ... cells wherever they may be in the body. Michael ... College of Veterinary Medicine, says being able to target ...
(Date:5/21/2013)... Chemical Society (ACS), the world,s largest scientific society, ... Meeting & Exposition, September 8-12, 2013, in Indianapolis, ... Convention Center and at area hotels. , With ... span science,s horizons from astronomy to zoology ... online journalists a rich assortment of spot news ...
Breaking Biology News(10 mins):MU researchers develop radioactive nanoparticles that target cancer cells 2
... central to fully understanding and modeling the pelagic (open ocean) ... numerical study conducted by the University of Miami (UM) incorporates ... creating a powerful tool that spells out how larvae use ... after being out on the open ocean. The new ...
... ,Brain freeze, is a nearly universal experiencealmost everyone has felt ... cream or slurp of ice-cold soda on the upper palate. ... phenomenon. Since migraine sufferers are more likely to experience brain ... freeze may share a common mechanism with other types of ...
... (New York, NY, April 22, 2012) Researchers at ... pathway that controls the retention and release of the ... normal and abnormal neurologic development and could eventually lead ... findings, from a collaborative effort of the laboratories of ...
Cached Biology News:Fish larvae find the reef by orienting: The earlier the better 2Fish larvae find the reef by orienting: The earlier the better 3Changes in brain's blood flow could cause 'brain freeze' 2Changes in brain's blood flow could cause 'brain freeze' 3'Housekeeping' mechanism for brain stem cells discovered 2'Housekeeping' mechanism for brain stem cells discovered 3
(Date:5/20/2013)... Mechanicsburg, Pa (PRWEB) May 20, 2013 ... controller with ramp/soak capabilities. The 5R6-900 benchtop controller ... enclosure, the device can be plugged into the wall ... own power supply. This distinctive detail makes the device ... , The laboratory temperature controller can also be ...
(Date:5/20/2013)... 20, 2013  (PSHR) Pacific Shore Holdings, Inc. ... across a broad range of product categories lines, ... relations firm, BlueWater Advisory Group, to provide strategic ... process, and to direct the company,s outreach and ... Matthew Mills , Pacific Shore ...
(Date:5/20/2013)... With bed bugs' presence come problems in ... bugs need to be eliminated, one must make sure that ... health. And so to help bed bug sufferers get that ... of bed bugs without using harmful pesticides. In it, ... called Bed Bug Bully. , According to My Cleaning Products, ...
(Date:5/20/2013)... 2013   Flexion Therapeutics , Inc. today announced ... to its management team as chief financial officer. ... management experience with biotechnology and medical device companies. ... financial officer for Novavax (NASDAQ: NVAX ) ... $250 million through a combination of investment funding and ...
Breaking Biology Technology:New Laboratory Temperature Controller by Oven Industries 2Pacific Shore Holdings Retains Investor Relations Firm 2New Non Pesticide Discovery on How to Get Rid of Bed Bugs Tipped by My Cleaning Products 2Flexion Therapeutics Names Frederick Driscoll Chief Financial Officer 2
... simple peptides can organize into bi-layer membranes. The ... chemical inventory and the organizational scaffolding essential to life. ... kind of membranes needed to create long-range order," says ... paper recently published by the German Chemical Society,s ...
... /PRNewswire-FirstCall/ - Oncothyreon Inc. (NASDAQ: ONTY ) (the "Company") today ... per basic and diluted share for the quarter ended March ... or $0.13 per basic and diluted share for the ... result of a decrease in fair value of warrant liability of ...
... LEIDEN, The Netherlands , May 6, ... NASDAQ: CRXL ; Swiss,Exchange: CRX) today announced the ... to supply its paediatric vaccine Quinvaxem(R) to the developing,world. ... the Millennium Development Goals set by the United Nations, ...
Cached Biology Technology:Peptides may hold 'missing link' to life 2Peptides may hold 'missing link' to life 3Oncothyreon reports first quarter 2010 financial results 2Oncothyreon reports first quarter 2010 financial results 3Oncothyreon reports first quarter 2010 financial results 4Oncothyreon reports first quarter 2010 financial results 5Crucell Announces New Award of $110 Million for Paediatric Vaccine Quinvaxem(R) by UNICEF to Support Vaccination Programs in the Developing World 2Crucell Announces New Award of $110 Million for Paediatric Vaccine Quinvaxem(R) by UNICEF to Support Vaccination Programs in the Developing World 3Crucell Announces New Award of $110 Million for Paediatric Vaccine Quinvaxem(R) by UNICEF to Support Vaccination Programs in the Developing World 4
... bioassays for interferons are cytopathic effect inhibition assays, ... Sample types include; tissue culture supernatents; serum from ... assays, one unit is defined as the quantity ... cytopathic effect of viral infection by 50%. ...
HyPro 20 system for slide hybridization. 20 slide capacity. Active vibration system, slide rack and humidity chamber. Ideal for microarray and in situ hybridization....
... bioassays for interferons are cytopathic effect inhibition assays, ... Sample types include; tissue culture supernatents; serum from ... assays, one unit is defined as the quantity ... cytopathic effect of viral infection by 50%. ...
Request Info...
Biology Products: