Navigation Links
Not quite 'roid rage
Date:9/29/2011

Fruit fly aggression is correlated with smaller brain parts, involves complex interactions between networks of important genes, and often cannot be controlled with mood-altering drugs like lithium.

Those are the results of a painstaking study conducted by researchers at North Carolina State University and colleagues in Belgium who are trying to discover what happens in the genes and brains of hyper-aggressive flies and how that differs from what takes place in more passive fly cousins.

Dr. Trudy Mackay, William Neal Reynolds Distinguished University Professor of Genetics and a co-lead author of a paper published this week in Proceedings of the National Academy of Sciences, says that the findings in the fruit fly could one day lead to helping humans think of Alzheimer's patients who suddenly become more aggressive by providing a framework of how complex gene interactions affect behavior. Fruit flies are model organisms for studying genes and traits like aggression.

In the study, the researchers showed that making changes, or mutations, to a handful of genes made some passive flies aggressive and made some aggressive flies really aggressive. They also showed the effects of mating flies with different mutations to see which mutant combinations had larger effects on aggression.

The researchers also showed that certain portions of the fly brain the so-called mushroom bodies, which affect locomotion, experience and memory were smaller in the hyper-aggressive flies.

The study also showed that calming did not necessarily come through chemistry, as doses of lithium soothed some but not all of the aggressive flies. These mixed results were also evident when flies were given two other types of calming drugs.

"This study shows that these brain networks are not simple, and that you can't look at just one gene at a time," says study co-author Dr. Robert Anholt, William Neal Reynolds Professor of Biology at N
'/>"/>

Contact: Dr. Trudy Mackay
trudy_mackay@ncsu.edu
919-515-5810
North Carolina State University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Induced neural stem cells: Not quite ready for prime time
2. Preventing cancer, quite naturally
3. Anabolic steroids provide a competitive edge in power lifting years after doping has ended
4. Extinction by asteroid a rarity
5. Smoking during pregnancy may impair thyroid function of mom and fetus
6. Study finds rescue course of antenatal steroids improves outcome in premature babies
7. First comprehensive guidelines for managing medullary thyroid carcinoma published in Thyroid journal
8. Plants on steroids: Key missing link discovered
9. Stem cell success points to way to regenerate parathyroid glands
10. Proposed mission would return sample from asteroid time capsule
11. The fight against uterine fibroid tumors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Not quite 'roid rage
(Date:9/18/2014)... ANTONIO, September 18, 2014 New research into the ... causes a severe hemorrhagic disease in humans similar to ... essential for CCHFV infection. This discovery has the potential ... the pathogen. , The research, reported in ... Pathogens and conducted by scientists at the Texas ...
(Date:9/18/2014)... researchers from McGill University and the Quebec government ... ,microbeads, Canadian Journal of Fisheries and Aquatic ... cosmetics, household cleansers, or industrial cleansers, to which ... their small size and buoyancy, they may readily ... a global contaminant in the world,s oceans, but ...
(Date:9/18/2014)... how many times it,s demonstrated, it,s still hard ... , But by using a signaling system called ... behavior to suit their population. In short, some ... and act accordingly. , Once the population of ... from innocuous to pathogenic, or from unhelpful to ...
Breaking Biology News(10 mins):Research milestone in CCHF virus could help identify new treatments 2Microplastic pollution discovered in St. Lawrence River sediments 2Researchers study vital 'on/off switches' that control when bacteria turn deadly 2Researchers study vital 'on/off switches' that control when bacteria turn deadly 3
... nannies help out, especially if they,ve been sneaking ... displays cooperative breeding behavior, where non-parents contribute to ... now, it was assumed that male subordinates never gained ... 12, in the online journal PLoS ONE , ...
... , This release is available in French ... Concordia University professors have received new funding to advance research ... of a peer committee, Canada Research Chairs were awarded to ... The announcement was made at Concordia in the ...
... of investigators from the University of Utah has received a ... to fund novel research that may help to uncover a ... multiple sclerosis. These studies will use an advanced technology called ... of primary progressive multiple sclerosis. Multiple sclerosis (MS), which ...
Cached Biology News:Recognition for 7 Concordia professors 2NIH grant will allow researchers to look for viral cause of most severe form of multiple sclerosis 2
(Date:9/18/2014)... 2014 OMICS Group International invites ... participate in the ‘Open Access Week’ by actively ... OMICS Group Pharma Journals from 20-26th October, ... fastest emerging Sciences, accelerating with a tremendous speed ... the globe. The industry is gearing with innovation ...
(Date:9/18/2014)... lab can be pretty expensive. Now a team led ... an open-source library of designs that will let scientists ... equipment: the syringe pump. , Syringe pumps are used ... delivery or mixing chemicals in a reaction. They can ... Joshua Pearce and his team of Michigan Tech students ...
(Date:9/18/2014)... we touch in the course of a day ... medicines, rely on the chemical industry to turn ... farm products into valuable chemicals that are the ... Dr Sarina Sarina, who achieved outstanding progress in ... ambient temperature using light instead of fossil fuels, ...
(Date:9/18/2014)... Pipette.com announces brand new ... and AccuPet brand of pipettes. Micropipettes are ideal ... less and are a great tool for molecular ... The micropipette promotions were designed to offer a ... to help customers find the right solution. Brands ...
Breaking Biology Technology:Pharma and Omics Journals to Address Global Challenges during Open Access Week 2Pharma and Omics Journals to Address Global Challenges during Open Access Week 3Doing science just got cheaper -- and faster 2Using solar energy to turn raw materials into ingredients for every day life 2Major Pipette Distributor Pipette.com Announces Promotions on Sartorius/Biohit, Socorex, Capp, and AccuPet Micropipettes 2Major Pipette Distributor Pipette.com Announces Promotions on Sartorius/Biohit, Socorex, Capp, and AccuPet Micropipettes 3
... Skills Related to Nutrition Care in Mosby,s ... Organization Elsevier/MC Strategies , a pioneer ... organizations announced today its collaboration with the American ... review and amend the nutrition-related skills in Mosby,s Nursing ...
... design, University at Buffalo chemists have synthesized tiny, molecular ... nanomaterials. , Sculpted from a special kind of molecule ... organic tubes whose interior walls carry a negative charge. ... positively charged particles. , In addition, because UB scientists ...
... Levi & Korsinsky is investigating potential claims on behalf ... California, Inc. ("PacBio" or the "Company") (NASDAQ: ... For more information, click here: http://zlk.9nl.com/pacific-biosciences-california-pacb/ ... that the Company failed to disclose the following: (a) ...
Cached Biology Technology:Elsevier Collaborates with the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) 2Elsevier Collaborates with the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) 3Chemists become molecular sculptors, synthesizing tiny, molecular traps 2Chemists become molecular sculptors, synthesizing tiny, molecular traps 3The Law Firm of Levi & Korsinsky, LLP Launches an Investigation Into Possible Securities Laws Violations by Pacific Biosciences of California, Inc. 2
... aptamer screening and binding optimization and built ... on-chip synthesis platform. These microarrays are available ... Microarray Service. Probe Content ... greater than 1500 known aptamer sequences. Add ...
... mouse embryonic stem cells to dopaminergic neurons. ... where they are mainly located in the ... the retrorubral field. These dopaminergic (DA) neurons ... ( e.g.projections to the caudate nucleus, putamen ...
... aptamer screening and binding optimization and built ... on-chip synthesis platform. Thousands of customer specified ... LC Sciences can provide assistance with custom ... part of our comprehensive DNA/RNA Aptamer Microarray ...
... Microarrays designed for DNA aptamer screening ... flexible and powerful Paraflo microfluidic on-chip synthesis ... be synthesized on-chip and LC Sciences can ... microarrays are available as part of our ...
Biology Products: