Navigation Links
Not all women in breast cancer families share high risk
Date:11/1/2011

Mothers, sisters and daughters from breast cancer families with known genetic mutations do not all share the same high risk of developing the disease, according to a new international study involving the University of Melbourne.

Women with the breast cancer genetic mutations BRCA1 or BRCA2 are at least 10 times more likely to develop breast cancer than the average woman.

The new study found that women who do not have a genetic mutation, but are closely related to women who do have genetic mutations are at an average risk of developing the disease.

Professor John Hopper from the School of Population Health, University of Melbourne, who led the Australian component of the study, said some women in this scenario were worrying unnecessarily.

"Our study revealed that these women have an average risk of developing the disease as opposed to the high risk of their mutation-carrying close relatives and hence do not need to worry unnecessarily and over screen to detect the disease," he said.

"These findings go against a 2007 clinic-based study in the UK which claimed that all women in breast cancer families with known genetic mutations are at increased risk of developing the disease even if they don't carry the family-specific mutation," he said.

"Our results revealed there was no evidence of increased breast cancer risk for non-carriers of the genetic mutations, certainly not the five-fold increased risk suggested by the authors of the 2007 study."

The international study is the largest analysis to date of breast cancer risk for non-carriers of family specific breast cancer mutations. It was led by Professor Alice Whittemore from Stanford University School of Medicine, USA and was published today in the Journal of Clinical Oncology.

More than 3000 breast cancer families from the population at large were analysed for their genetic risk of the disease. Researchers compared the risk of br
'/>"/>

Contact: Rebecca Scott
rebeccas@unimelb.edu.au
61-383-440-181
University of Melbourne
Source:Eurekalert

Page: 1 2

Related biology news :

1. Improved living environments can reduce health problems for women and children
2. Womens heart disease tied to small blood vessels
3. 11 women scientists announced as winners of Elsevier Foundation OWSD awards
4. Innovating to improve women and childrens health
5. Increased celiac disease prevalence in women with unexplained infertility
6. SUNY Downstate researchers identify possible new targets for treating pain in women
7. Pregnant women in Vancouver may not be getting enough vitamin D
8. B-cell discovery suggests why women suffer more autoimmune disease
9. U of M researchers may have discovered key to help women fight infections during pregnancy
10. Greater seizure frequency seen in women with epilepsy during anovulatory cycle
11. PSA test for men could get a second life for breast cancer in women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/1/2015)... -- NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the ... mobile commerce market, announces the second shipment of a ... early access pre-order customers. Feedback from ... including Walmart, Target, AT&T, Dunkin, Donuts, Stop & Shop ... all outlets and very easy to use. Several users ...
(Date:3/31/2015)... --  Guidepoint , a leading global research services firm, ... TRACKER, part of the Guidepoint TRACKER suite ... device and therapeutics markets. The Post-Surgical Pain Management TRACKER ... share, and adoption rates across three major modalities used ... The Post-Surgical Pain Management TRACKER will provide length ...
(Date:3/24/2015)... , Mar. 24, 2015 Research and Markets ... of the "Global Iris Recognition Market 2015-2019" ... the Global Iris Recognition market to grow at a ... This report covers the present scenario and the ... the period 2015-2019. To calculate the market size, the ...
Breaking Biology News(10 mins):NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 2NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 3NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 4Guidepoint Launches Post-Surgical Pain Management TRACKER 2Guidepoint Launches Post-Surgical Pain Management TRACKER 3Global Iris Recognition Market 2015-2019 with 3M Cogent, Bioenable Technologies, Cross Match Technology, Iris ID Systems & Safran Dominating 2
... study has confirmed that research done with zebrafish may be ... genetic basis of cancer and the mutations that can lead ... whose function is essential to preventing tumors. , The findings ... Academy of Sciences, by researchers from Oregon State University and ...
... of how humans differ from one another at the DNA ... recent evolution of our species, according to researchers from Cornell ... study published in the Oct. 20 issue of the journal ... not only among 39 humans but also between the humans ...
... a UN report provides definitive answers and ways to repair ... could eventually die of radiation exposure from the Chernobyl nuclear ... team of more than 100 scientists has concluded. , As ... attributed to radiation from the disaster, almost all being highly ...
Cached Biology News:Zebrafish may hold key to improved cancer research 2Zebrafish may hold key to improved cancer research 3Cornell finds natural selection in humans 2Cornell finds natural selection in humans 3Chernobyl: The true scale of the accident 2Chernobyl: The true scale of the accident 3Chernobyl: The true scale of the accident 4Chernobyl: The true scale of the accident 5Chernobyl: The true scale of the accident 6Chernobyl: The true scale of the accident 7Chernobyl: The true scale of the accident 8Chernobyl: The true scale of the accident 9Chernobyl: The true scale of the accident 10Chernobyl: The true scale of the accident 11Chernobyl: The true scale of the accident 12Chernobyl: The true scale of the accident 13Chernobyl: The true scale of the accident 14Chernobyl: The true scale of the accident 15Chernobyl: The true scale of the accident 16
(Date:5/1/2015)... SAN DIEGO , May 1, 2015 /PRNewswire/ ... biotechnology company engaged in the development of biosimilar ... proteins, announced today that its first quarter 2015 ... 14, 2015, before the open of market. At 8:30 ... conference call to discuss the financial results and ...
(Date:5/1/2015)... -- Albany Molecular Research Inc. (NASDAQ: AMRI ) ... President and Chief Executive Officer, will present at the ... on Wednesday, May 13, 2015 at 4:20 p.m. ET. ... can be accessed at AMRI,s Investor Relations web site at ... be archived for 90 days following the live presentation. ...
(Date:4/30/2015)...  Roka Bioscience, Inc. (NASDAQ: ROKA ), a ... for the detection of foodborne pathogens, announced plans to ... 2015 on May 7, 2015 after the close of ... host a conference call at 4:30 p.m. Eastern Time ... financial results. During the conference call, material information concerning ...
(Date:4/30/2015)... 2015 Nitto Avecia, a leading ... increased capacity and production capability to serve biotechnology ... and service fulfillment continues to drive Nitto Avecia ... throughput capacities. , In Fall 2014, ... process equipment at its Milford, MA facility, which ...
Breaking Biology Technology:Pfenex To Report First Quarter 2015 Results and Provide Business Update on Thursday, May 14, 2015 2AMRI to Present at the Bank of America Merrill Lynch 2015 Health Care Conference 2Roka Bioscience to Report First Quarter 2015 Financial Results On May 7, 2015 2Biotechnology Manufacturer Nitto Avecia Expands Capacity to Meet Client Demand 2
... MedPredict has published,"Thought Leader Insight & Analysis: Alzheimer,s ... and biotech companies with a,stake in the market ... "Given the size of this patient population ... control, it is not surprising to see the,large ...
... Therapy Better Option for Humans, EGG HARBOR ... the first time, The British Institute of Homeopathy, ... to U.S. medical and,homeopathic practitioners for a low-introductory ... cell therapy is more advantageous because,it does not ...
... 28 Carl Icahn confirmed today that,entities affiliated with ... to nominate three persons at Biogen,s forthcoming 2008 Annual,Meeting ... currently,has a staggered board of twelve directors, and there ... Icahn stated that "We are taking this action because ...
Cached Biology Technology:New Report Tackles the Changing Landscape for Alzheimer's Diagnostics and Treatments 2Icahn Confirms Intention to Nominate Three Directors at Biogen 2Icahn Confirms Intention to Nominate Three Directors at Biogen 3
Thermo Labsystems offers a basic reader for 96-well microplates that is especially adapted for ELISA and other colorimetric assays....
Features , Designed to assist users in applying domed caps to tube strips and plates , Minimises the pressure required to seal the caps effectively , Enables multiple tubes to be sealed simultaneousl...
Lysozyme C (W-20)...
... B4i ventilated and BR4i refrigerated multifunction centrifuges are ... operation at a low sound level with a ... biocontainment. Their AUTO-LOCK rotor exchange system without tools ... use within seconds. Instant rotor exchange ...
Biology Products: