Navigation Links
Northwestern nets NIH grant to tailor drugs to patients' genome
Date:8/19/2011

CHICAGO --- Northwestern University Feinberg School of Medicine researchers have received a $762,000 grant from the National Institutes of Health (NIH) to tailor drug treatments to patients' genomic information. The grant, provided to members of the Electronic Medical Records and Genomics (eMERGE) network, is from the National Human Genome Research Institute (NHGRI), part of the NIH, which supports research by the network's seven institutions and coordinating center.

"This new eMERGE grant is an important step in connecting genomic information to high-quality data in electronic medical records during the clinical care of patients, and Northwestern is proud to be at the forefront of this initiative," says Rex L. Chisholm, vice dean of scientific affairs and graduate education, the Adam and Richard T. Lind Professor of Medical Genetics and a professor in cell and molecular biology at the Center for Genetic Medicine and Surgery at the Feinberg School. "The ultimate goal is to identify the genetic contributions to disease and equip health centers with the information and tools needed to apply genomic knowledge to patient care."

The grant enables investigators to identify genetic variants associated with 40 more disease characteristics and symptoms, using genome-wide association studies across the entire eMERGE network. DNA from about 32,000 participants will be analyzed in each study. Genome-wide association studies represent a powerful approach researchers can use to study hundreds of thousands of genetic variants in people with and without certain health conditions to identify genes that cause or contribute to diseases.

eMERGE researchers will then use the genomic information in clinical care. With patient consent, researchers may use information about genetic variants involved in drug response to adjust patient medications. In addition, eMERGE researchers who discover patients harboring genetic variants associated with diseases such as diabetes or cardiovascular disease will intervene to prevent, diagnose and/or treat such diseases.

The first phase of eMERGE, which wrapped up in July, demonstrated that data about disease characteristics in electronic medical records and patients' genetic information can be used in large genetic studies. So far, the eMERGE network has identified genetic variants associated with dementia, cataracts, high-density lipoprotein (HDL) cholesterol, peripheral arterial disease, white blood cell count, type 2 diabetes and cardiac conduction defects.


'/>"/>

Contact: Marla Paul
marla-Paul@northwestern.edu
312-503-8928
Northwestern University
Source:Eurekalert

Related biology news :

1. New dinosaur species possible in Northwestern Alberta
2. The fragility of the worlds coral is revealed through a study of the Northwestern Hawaiian Islands
3. ASHG awards $10,000 genetics education research grant to Maurice Godfrey of University of Nebraska
4. OU-led research team receives $1.28 million grant from DOE
5. FASEB MARC program announces the travel award recipients for the 2011 Leadership Development and Grant Writing Seminar for graduate students, postdoctoral fellows and new assistant professors
6. MSU professor launches new field of water research, nets $2.2 million NSF grant
7. Lincoln Park Zoo awarded 2 significant grants for science education
8. $3 million grant to aid minorities with uncontrolled diabetes
9. The Guy Harvey Ocean Foundation awards research grant to RJ Dunlap Marine Conservation Program
10. CWRU receives $2.1 million NIH grant to expand cystic fibrosis research models
11. St. Josephs scientist receives grant for post-partum research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/3/2017)... 3, 2017  Data captured by IsoCode, ... detected a statistically significant association between the ... treatment and objective response of cancer patients ... predict whether cancer patients will respond to ... well as to improve both pre-infusion potency testing ...
(Date:3/29/2017)... 29, 2017  higi, the health IT company that ... North America , today announced a Series B ... of EveryMove. The new investment and acquisition accelerates higi,s ... to transform population health activities through the collection and ... higi collects and secures data today on behalf ...
(Date:3/24/2017)... Mar 24, 2017 Research and Markets has ... Market Analysis & Trends - Industry Forecast to 2025" report ... ... at a CAGR of around 15.1% over the next decade to ... report analyzes the market estimates and forecasts for all the given ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... , ... They call it the “hairy ball.” It’s an ... a system of linkages and connections so complex and dense that “it looks ... at Worcester Polytechnic Institute (WPI) and director of the university’s bioinformatics and computational ...
(Date:10/12/2017)... FL (PRWEB) , ... October ... ... (RPS®) today announces publication of a United States multicenter, prospective clinical study ... use, disposable, point-of-care diagnostic test capable of identifying clinically significant acute bacterial ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... analysis platform specifically designed for life science researchers to analyze and interpret ... Rosalind Franklin, who made a major contribution to the discovery of the ...
(Date:10/11/2017)... ... , ... Personal eye wash is a basic first aid supply for any work environment, but ... do you rinse first if a dangerous substance enters both eyes? It’s one less decision, ... its unique dual eye piece. , “Whether its dirt and debris, or an acid or ...
Breaking Biology Technology: