Navigation Links
Normal-looking sperm may have serious damage; scientists urge more care in selection
Date:7/8/2008

This release is available in Spanish.

Barcelona, Spain: Intracytoplasmic sperm injection (ICSI), where a single sperm is injected into an egg to fertilise it, is increasingly used to help infertile men father children. Although the sperm chosen for the procedure may appear quite normal, researchers in the US have found that many of them in fact have DNA damage, which can decrease the chances of pregnancy.

Mr. Conrado Avendao, from the Jones Institute for Reproductive Medicine, Norfolk, Virginia, USA, and colleagues studied a group of infertile men with moderate and severe teratozoospermia, where most of the sperm looks abnormal. He told the 24th annual conference of the European Society of Human Reproduction and Embryology today (Tuesday 8 July) that, in this group of men, the embryologist would normally select the 'best looking' sperm for injection. "This would typically be done by analysing the sperm's shape under a microscope," he said. "A 'good' sperm by this criterion would have a regular oval head and a long straight tail. However, our research has shown that appearances can be deceptive."

Mr. Avendao and colleagues studied sperm from ten infertile men and found that, despite appearing to be completely normal, many of them had DNA damage (DNA fragmentation). "In routine ICSI procedure, the embryologist chooses the best-looking sperm under the microscope, but it could be damaged," he said. "DNA-damaged sperm has a highly deleterious effect on the ability to achieve a pregnancy. Even if damaged sperm are used and the woman becomes pregnant, the chances of miscarrying are significantly higher."

The researchers compared levels of DNA fragmentation in sperm from the infertile group with that from fertile men. The study was performed by a simultaneous examination of normal sperm morphology using face contrast and DNA fragmentati
'/>"/>

Contact: Mary Rice
mary@mrcommunication.org
34-932-308-810
European Society for Human Reproduction and Embryology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Wiggle room: Cornell researcher borrows idea from sperm to provide energy for nanoscale robots
2. Mutant sperm guide clinicians to new diseases
3. Primate sperm competition: speed matters
4. Bacterial slime helps cause serious disease
5. Oceanic sharks worldwide at serious risk from high-seas fishing, rising demand for shark products
6. West Nile virus spread through nerve cells linked to serious complication
7. Study finds blocking angiogenesis signaling from inside cell may lead to serious health problems
8. Biodiversity maps developed by UCSD scientists will help guide conservation measures in East Africa
9. Scientists integrate data in three dimensions to study climate effects on young fish
10. Scientists set out to measure how we perceive naturalness
11. Scientists reveal the key mechanisms for affinity between transient binding proteins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... 2014   LaunchKey , the first decentralized mobile authentication ... of Things era, today announced the close of $3 ... led by Metamorphic Ventures with participation from ENIAC Ventures, ... others.  LaunchKey has raised $4 million to date, and ...
(Date:12/17/2014)... , Dec. 16, 2014 Research and Markets ... "Global Chemical Sensor Market 2015-2019" report to ... One major trend upcoming in this market ... applications. Chemical sensors help in recording of patient data ...
(Date:12/11/2014)... blood pressure plays a role in human health has been ... for high blood pressure – was first described as a ... used in measuring blood pressure was invented in 1896. ... its triggers and its effects. In fact, recent findings have ...
Breaking Biology News(10 mins):LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4
... GSA Bulletin articles posted online between 2 ... San Andreas fault, California; Tibet; Mongolia; Maine; the Owyhee ... Sinai Peninsula, Egypt; British Columbia; the southern Rocky Mountains; ... "big crisis" in the history of life on Earth; ...
... Military uniforms of the future may offer a ... research by teams at the University of Massachusetts Amherst ... fabric that repels chemical and biological agents. UMass ... with team leader Francesco Fornasiero of Lawrence Livermore National ...
... The hydraulic system of trees is so finely-tuned that ... lead to catastrophic failure in many species. A recent ... Biological Sciences Amy Zanne finds that those systems in ... of their safety threshold, making forest ecosystems vulnerable to ...
Cached Biology News:GSA Bulletin: From Titan to Tibet 2GSA Bulletin: From Titan to Tibet 3GSA Bulletin: From Titan to Tibet 4GSA Bulletin: From Titan to Tibet 5GSA Bulletin: From Titan to Tibet 6GSA Bulletin: From Titan to Tibet 7GSA Bulletin: From Titan to Tibet 8GSA Bulletin: From Titan to Tibet 9GSA Bulletin: From Titan to Tibet 10GSA Bulletin: From Titan to Tibet 11GSA Bulletin: From Titan to Tibet 12GSA Bulletin: From Titan to Tibet 13GSA Bulletin: From Titan to Tibet 14GSA Bulletin: From Titan to Tibet 15GSA Bulletin: From Titan to Tibet 16GSA Bulletin: From Titan to Tibet 17GSA Bulletin: From Titan to Tibet 18GSA Bulletin: From Titan to Tibet 19GSA Bulletin: From Titan to Tibet 20GSA Bulletin: From Titan to Tibet 21Developing 'second skin' military fabric to repel chemical and biological agents 2Developing 'second skin' military fabric to repel chemical and biological agents 3Increasing drought stress challenges vulnerable hydraulic system of plants, GW professor finds 2
(Date:1/22/2015)... Selexis SA, a serial innovation company ... (RCBs) used for drug discovery to commercial manufacturing, announced ... Next-Generation Sequencing (NGS) data packages. The NGS ... by ensuring the integrity of the gene, validation of ...
(Date:1/22/2015)... CAMBRIDGE, Mass. , Jan. 22, 2015   GenoSpace , ... suite of tools to enable the broad use of genomic, ... today announced the appointment of Michelle Munson , CEO ... independent director. Logo - http://photos.prnewswire.com/prnh/20150122/170713 ...
(Date:12/24/2014)... , Dec. 24, 2014  Vermillion, Inc. (Nasdaq:   ... disease, announced today that the Company closed its ... Investment Management, Jack W. Schuler , Birchview ... were $10.5 million, before offering expenses.  The proceeds ...
(Date:12/24/2014)... MA (PRWEB) December 23, 2014 ... is designed to introduce cutting edge communication technology, ... of platform upgrades. This webinar series demonstrates online ... quest to leverage web conferencing’s most innovative and ...
Breaking Biology Technology:Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2GenoSpace Expands Board with Appointment of Michelle Munson 2Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3
... Texas, April 23 DFB Pharmaceuticals, Inc., has announced ... President Business Development and Corporate Finance. Mr. Lea ... for the company."Since joining DFB in 2002, Maxwell has ... affiliate businesses," said Michael A. Patterson, Chief Financial Officer ...
... International, a leading Clinical Research Organization, announces it will ... April 28-30, 2009 in Orlando Florida. PRA,s Greg Guarasci, ... RFP Management & Contracting with CROs to Minimize Change ... on his extensive experience with contracting, Mr. Guarasci will ...
... EVRY, France, April 23 The 2009 edition ... will take,place in Atlanta from May 18th-20th. Genopole(R) ... a delegation from the Paris Ile-de-France Region.,Seven of ... and Xentech) and the I-Stem,research lab will, attend. ...
Cached Biology Technology:DFB Pharmaceuticals Appoints Maxwell Lea to Vice President Business Development and Corporate Finance 2PRA International Presents Key Budgeting Strategies at 18th Annual CRO Partnerships Conference 2Genopole(R) to Accompany 7 Companies and a Research lab to BIO Atlanta 2
...
...
Mouse polyclonal antibody to TNPO2 - transportin 2 (importin 3, karyopherin beta 2b)...
Mouse monoclonal antibody to CDC2L5 - cell division cycle 2-like 5 (cholinesterase-related cell division controller)...
Biology Products: