Navigation Links
Nonstick and laser-safe gold aids laser trapping of biomolecules
Date:6/17/2009

00 feet up and hoping it will land tires down. If the molecule lands in the wrong orientation, it wont be active or, worse, it will only partially work, Perkins says.

Ideally, scientists want to attach biomolecules in an optimal pattern on an otherwise nonstick surface. Gold posts are easy to lay down in desired patterns at the nanometer scale. Perkins group attached the DNA to the gold with sulfur-based chemical units called thiols (widely used in nanotechnology), an approach that is mechanically stronger than the protein-based bonding techniques typically used in biology. The JILA scientists used six thiol bonds instead of just one between the DNA and the gold posts. These bonds were mechanically strong enough to withstand high-force laser trapping and chemically robust enough to allow the JILA team to coat the unreacted gold on each nanopost with a polymer cushion, which eliminated undesired sticking. Now you can anchor DNA to gold and keep the rest of the gold very nonstick, Perkins says.

Moreover, the gold nanoposts were small enoughwith diameters of 100 to 500 nanometers and a height of 20 nanometersthat the scientists could avoid hitting the posts directly with lasers. Like oil and water, traditionally laser tweezers and gold dont mix. By making very small islands of gold, we positioned individual molecules where we wanted them, and with a mechanical strength that enables more precise and additional types of studies, Perkins says.


'/>"/>

Contact: Laura Ost
laura.ost@nist.gov
303-497-4880
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

Page: 1 2

Related biology news :

1. How nonstick bugs evade natural fly paper
2. LaserCard Corporation Announces Expansion of Middle East Project
3. Silicon Valley Technology Leaders LaserCard Corporation and Tesla Motors Sign LaserPass Secure Access Deal
4. New insights into how lasers cut flesh
5. Fine-tuning lasers to destroy blood-borne diseases like AIDS
6. Laser can spot illness before symptoms appear
7. Cleaner diesels thanks to laser light
8. Detecting dangerous chemicals with lasers, exploring the brains circuitry with light and more
9. Argonne scientists use lasers to align molecules
10. Laser fluorescence could find life on Mars
11. Life under the laser
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Nonstick and laser-safe gold aids laser trapping of biomolecules
(Date:5/25/2015)... 25, 2015  Australia,s market for wearable technologies is ... saw the advent of several trials and prototypes. The ... is expected to ignite interest in wearables as well ... Australia . This in turn will spur greater ... new partnerships amongst vendors and distributors. ...
(Date:5/21/2015)... , May 21, 2015 ... "Thermal Imaging Market by Solutions (Hardware, Software, Services), by ... Automotive & others), by End-Users (Military & Defense ... by MarketsandMarkets, Thermal Imaging Market is expected to ... Million by 2020, at a Compound Annual Growth ...
(Date:5/20/2015)... Conn. , May 20, 2015 NXT-ID, ... announces that its wholly owned subsidiary, 3D-ID LLC, a ... under Team Battelle for the biometrics technology portion of ... Suite Contract from the Department of the Army. ... recognition products developed for government, law enforcement and security ...
Breaking Biology News(10 mins):Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 2Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 3Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 4Thermal Imaging Market Worth $9,998.9 Million by 2020 2Thermal Imaging Market Worth $9,998.9 Million by 2020 3Thermal Imaging Market Worth $9,998.9 Million by 2020 4NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 2NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 3
... Jrgen Kjems and Morten Trillingsgaard Ven, Department of Molecular ... contribute to an article on microRNA-128 just published in ... was possible to control the amount of microRNA-128 in ... "If microRNA-128 is kept down in these neurons in ...
... Ariz. A group of researchers from Arizona State University ... in the study of human proteins that could open up ... work is being reported in this week,s Science ... G-protein-coupled receptors," the team reports that they have been successful ...
... New York have reported the successful transformation of vegetable ... a structuring agent. The findings portend the development of ... acids, which have been linked to coronary artery disease, ... College Professor of Chemistry George John, tested two sugar ...
Cached Biology News:New research provides insight into epilepsy 2ASU researchers develop new device to help image key proteins at room temperature 2ASU researchers develop new device to help image key proteins at room temperature 3CCNY chemists use sugar-based gelators to solidify vegetable oils 2
(Date:6/1/2015)... June 1, 2015  OncoSec Medical Inc. ("OncoSec") ... intratumoral cancer immunotherapies, today announced a collaboration with ... Veterinary Medicine to test ImmunoPulse™ IL-12 as an ... primary goals of the canine study are to ... of ImmunoPulse™ IL-12 and validate key clinical biomarkers. ...
(Date:6/1/2015)... Hutchison China MediTech Limited ... (publ) ("AstraZeneca"), Hutchison MediPharma Limited,s ("HMP") collaboration partner, ... clinical trial of HMP,s c-Met inhibitor savolitinib (AZD6094) ... cell lung cancer ("NSCLC"). AZD9291 is ... receptor (EGFR). Preliminary data on the activity of ...
(Date:5/31/2015)... , May 31, 2015 Halozyme ... company developing novel oncology and drug-delivery therapies, today ... clinical study of its investigational new drug PEGPH20 ... pancreatic cancer. The encouraging interim data ... Clinical Oncology annual meeting in an oral presentation ...
(Date:5/30/2015)... and RARITAN, N.J. ... international, multi-center, open-label, two-part, single-arm Phase 2 MMY2002 ... an investigational, human anti-CD38 monoclonal antibody – achieved ... (95% CI, 20.8-38.9), as assessed by an independent ... myeloma. The ORR was consistent among the pre-specified ...
Breaking Biology Technology:OncoSec Medical and UC Davis School of Veterinary Medicine Collaborate to Test Intratumoral Cancer Immunotherapy in Canine Soft Tissue Sarcoma 2OncoSec Medical and UC Davis School of Veterinary Medicine Collaborate to Test Intratumoral Cancer Immunotherapy in Canine Soft Tissue Sarcoma 3OncoSec Medical and UC Davis School of Veterinary Medicine Collaborate to Test Intratumoral Cancer Immunotherapy in Canine Soft Tissue Sarcoma 4Savolitinib (AZD6094) Preliminary Phase Ib Clinical Data in Lung Cancer Presented at the 2015 ASCO Annual Meeting 2Savolitinib (AZD6094) Preliminary Phase Ib Clinical Data in Lung Cancer Presented at the 2015 ASCO Annual Meeting 3Halozyme Phase 2 Clinical Study Of Investigational Drug PEGPH20 Shows Doubling Of Progression-free Survival And Improvement Trend In Overall Survival In High HA Metastatic Pancreatic Cancer Patients 2Halozyme Phase 2 Clinical Study Of Investigational Drug PEGPH20 Shows Doubling Of Progression-free Survival And Improvement Trend In Overall Survival In High HA Metastatic Pancreatic Cancer Patients 3Halozyme Phase 2 Clinical Study Of Investigational Drug PEGPH20 Shows Doubling Of Progression-free Survival And Improvement Trend In Overall Survival In High HA Metastatic Pancreatic Cancer Patients 4Halozyme Phase 2 Clinical Study Of Investigational Drug PEGPH20 Shows Doubling Of Progression-free Survival And Improvement Trend In Overall Survival In High HA Metastatic Pancreatic Cancer Patients 5Data Show Daratumumab Achieved a Pronounced Overall Response Rate as a Single-Agent with Tolerable Safety Profile in Heavily Pre-Treated Multiple Myeloma Patients 2Data Show Daratumumab Achieved a Pronounced Overall Response Rate as a Single-Agent with Tolerable Safety Profile in Heavily Pre-Treated Multiple Myeloma Patients 3Data Show Daratumumab Achieved a Pronounced Overall Response Rate as a Single-Agent with Tolerable Safety Profile in Heavily Pre-Treated Multiple Myeloma Patients 4Data Show Daratumumab Achieved a Pronounced Overall Response Rate as a Single-Agent with Tolerable Safety Profile in Heavily Pre-Treated Multiple Myeloma Patients 5Data Show Daratumumab Achieved a Pronounced Overall Response Rate as a Single-Agent with Tolerable Safety Profile in Heavily Pre-Treated Multiple Myeloma Patients 6Data Show Daratumumab Achieved a Pronounced Overall Response Rate as a Single-Agent with Tolerable Safety Profile in Heavily Pre-Treated Multiple Myeloma Patients 7
... for Talent is opening up. Tens of millions of people ... join, or are already in, the workforce - bringing expectations, ... Those organizations that can inspire the passion and harness the ... their competitors. Here's why. , ,Until recently, workers of ...
... note: Janet Dillione is president of the health services ... largest medical technology companies. She has something in common with Donna ... - both recently were named among the Top 25 women in ... are some excerpts from a recent WTN interview with Dillione. ...
... Court has issued several rulings that have eroded the strength ... v. AT&T , the Supreme Court delivered another blow by ... law governs domestically but does not rule the world. , , ... Court addressed Section 271(f) of the patent code, which prohibits a ...
Cached Biology Technology:Media-savvy workers: New front in the War for Talent 2Media-savvy workers: New front in the War for Talent 3Media-savvy workers: New front in the War for Talent 4Media-savvy workers: New front in the War for Talent 5Siemens health services president calls IT benefits unassailable 2Siemens health services president calls IT benefits unassailable 3Siemens health services president calls IT benefits unassailable 4Siemens health services president calls IT benefits unassailable 5Supreme Court limits foreign reach of U.S. patents 2Supreme Court limits foreign reach of U.S. patents 3Supreme Court limits foreign reach of U.S. patents 4
PEG 8000 is used in the precipitation of phage, isolation of plasmid DNA and the enhancement of blunt-ended ligation reactions....
Mouse Iduronate 2-Sulfatase Affinity Purified Polyclonal Ab Keywords: Sulfatases, Iduronate 2-Sulfatase, Mucopolysaccharidosis, Hunter Syndrome, Glycobiology Protein Family: Proteoglycan Regu...
An instrument that delivers an accurate and uniform amount of light energy to cells to photoactivate csiRNA products....
interferon-related developmental regulator 2...
Biology Products: