Navigation Links
Non-wovens as scaffolds for artificial tissue
Date:5/13/2009

This release is available in German.

When someone's knee hurts with every step it's a sign that the cartilage has been so badly damaged that the bones rub together when walking. Medical scientists are developing a technique to produce cartilage tissue artificially so that patients with such knee problems can walk free of pain again. The aim is also to make tendons and blood vessels in the laboratory. The research scientists place cells on a porous scaffold material, for example a non-woven made of polymer fibers. The cells can then grow on this frame and form tissue. Whether the cells will grow properly into tissue, however, depends on many factors. For instance, the cells only form cartilage if they are subjected to loads comparable with those in the body. To form cartilage the tissue needs to experience the pressure applied by every step. By contrast, blood vessel tissue needs the pulsation of the blood. The scientists reproduce these loads in the cell culture. When the artificial cartilage is inserted in the patient's knee the supporting scaffold is gradually resorbed and only the cartilage tissue remains.

While it is quite easy to produce npn-wovens from thin polymer fibers, it is difficult to describe these materials experimentally and theoretically. What forces do the cells experience when the non-woven is pulled or when a liquid passes through the fibre network? How do cells penetrate the non-woven? How do liquids permeate the non-woven? Research scientists at the Fraunhofer Institute for Mechanics of Materials IWM in Freiburg and Halle have developed a simulation model which answers these questions and characterizes the fleeces. "The simulation reproduces the mechanical properties of the fleeces and the transport processes the software can therefore also calculate how nutrients are transported to the cells and metabolic products are tr
'/>"/>

Contact: Dr. Raimund Jaeger
raimund.jaeger@iwm.fraunhofer.de
49-761-514-2284
Fraunhofer-Gesellschaft
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Smart scaffolds may help heal broken hearts
2. Development of an artificial simulator of the nervous system to do research into diseases
3. Red pandas reveal an unexpected (artificial) sweet tooth
4. Artificial cells, simple model for complex structure
5. TECNALIA uses artificial vision to improve recycling of electronic scrap metal
6. Biomedical researchers create artificial human bone marrow in a test tube
7. Scientists identify cell changes leading to impaired artificial kidney function
8. Evolved Machines Selected as a Prime Contractor for DARPA Program to Engineer an Artificial Olfaction System
9. Researchers design artificial cells that could power medical implants
10. Taking the next step toward advanced artificial limbs
11. Complex ocean behavior studied with artificial upwelling
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Non-wovens as scaffolds for artificial tissue
(Date:8/1/2014)... eye diseases is tricky enough. Knowing what causes them ... Now, University of Iowa researchers have created the most ... human eye long associated with blinding diseases, such as ... of proteins in the choroid, which supplies blood and ... By seeing differences in the abundance of proteins in ...
(Date:8/1/2014)... most diverse families in the ocean today -- marine ... more than 400 million years ago in the Silurian ... its modern members. This Geology study by ... on 25 July 2014, tracks the remarkable evolutionary expansion ... is origin, the Lucinidae family remained at very low ...
(Date:8/1/2014)... co-authors of a new study, including two Simon ... scientists, industry representatives and policymakers must collaborate closely ... shale gas development. Viorel Popescu and Maureen Ryan, ... Biological Sciences department, are among eight international co-authors ... in Ecology and the Environment . , Shale ...
Breaking Biology News(10 mins):A map for eye disease 2Symbiotic survival 2Symbiotic survival 3Symbiotic survival 4Symbiotic survival 5Symbiotic survival 6Symbiotic survival 7Symbiotic survival 8Symbiotic survival 9Symbiotic survival 10Symbiotic survival 11Symbiotic survival 12Symbiotic survival 13Symbiotic survival 14Scientists warn time to stop drilling in the dark 2Scientists warn time to stop drilling in the dark 3
... Colorado and TUSTIN, Calif., April 21, 2009--Peregrine ... biopharmaceutical company developing monoclonal antibodies for the ... today reported that two preclinical studies presented ... provided further confirmation of the immunomodulatory mechanisms ...
... 50 years as one of the most effective treatments ... been entirely sure exactly how it operates in the ... scientists suggests a mechanism for how Lithium works, opening ... tests on cells have shown that Lithium affects a ...
... MEDFORD/SOMERVILLE, Mass. -- A collaborative team of student designers, ... and Tufts University will use Earth Day as an ... a house that will be solar powered, attractive and ... April 22, at 11:00 a.m. at Sophia Gordon Hall ...
Cached Biology News:Peregrine's PS-targeting antibodies highlighted in AACR Annual Meeting studies 2Peregrine's PS-targeting antibodies highlighted in AACR Annual Meeting studies 3Peregrine's PS-targeting antibodies highlighted in AACR Annual Meeting studies 4Tufts students host Earth Day with groundbreaking ceremony for solar house 2Tufts students host Earth Day with groundbreaking ceremony for solar house 3
(Date:7/31/2014)... see through organs and even the entire body to ... cellular structures has been a long-time dream of biologists. ... 31st in the journal Cell has now ... making opaque organs, bodies, and human tissue biopsies transparent, ... protocols could pave the way for a better understanding ...
(Date:7/31/2014)... BLOOMINGTON, Ind. -- Chemists at Indiana University Bloomington ... in bricks-and-mortar fashion, a development with potential value ... as field-effect transistors and photovoltaic cells. , Their ... 3D Crystalline Solids and 2D Self-Assembled Crystals," has ... a journal of the Royal Society of Chemistry. ...
(Date:7/31/2014)... , July 31, 2014 According ... Research "Quantum Dots Market - Global Industry Analysis, Size, ... market was valued at USD 88.5 million in 2011, ... 2023, growing at a CAGR of 53.8% from 2013 ... Market Report at  http://www.transparencymarketresearch.com/quantum-dots.html Increasing demand ...
(Date:7/31/2014)... July 31, 2014 Graphite Metallizing Corporation ... temperature oven carts. These bearings are uniquely suited to ... ball bearings because of the high temperatures . ... help from the design engineers at Graphite Metallizing to ... process. During their manufacturing operation, pans containing blocks of ...
Breaking Biology Technology:See-through organs and bodies will accelerate biomedical discoveries 2Chemists demonstrate 'bricks-and-mortar' assembly of new molecular structures 2Chemists demonstrate 'bricks-and-mortar' assembly of new molecular structures 3Global Quantum Dots Market is Expected to Reach USD 8,246.8 Million in 2023: Transparency Market Research 2Global Quantum Dots Market is Expected to Reach USD 8,246.8 Million in 2023: Transparency Market Research 3Global Quantum Dots Market is Expected to Reach USD 8,246.8 Million in 2023: Transparency Market Research 4Graphite Metallizing Announces Bearings for High Temperature Oven Applications 2Graphite Metallizing Announces Bearings for High Temperature Oven Applications 3
... Nile Therapeutics,Inc. (OTC Bulletin Board: NILT.OB), a ... today announced the,appointment of Gregory W. Schafer to ... audit committee. Mr. Schafer is a seasoned biotechnology ... finance and operations., "We are delighted to ...
... Lentigen Corporation today announced,the appointment of Tim Ravenscroft ... chairman, commented, "The board of Lentigen,is delighted that ... are about to enter,clinical trials for our first ... particularly strong background and global leadership in,healthcare products ...
... Arno Therapeutics, Inc., a,privately held drug development ... license agreements with The Ohio State University,("OSU") for ... therapies for cancer., Pursuant to the license ... for the treatment of cancer, including OSU-03012 (NSC,D728209) ...
Cached Biology Technology:Nile Therapeutics Appoints Gregory W. Schafer to Board of Directors 2Nile Therapeutics Appoints Gregory W. Schafer to Board of Directors 3Lentigen Appoints Tim Ravenscroft as Chief Executive Officer 2Arno Therapeutics Completes License Agreements for the Exclusive Rights to Novel, Targeted Cancer Compounds 2Arno Therapeutics Completes License Agreements for the Exclusive Rights to Novel, Targeted Cancer Compounds 3
... The Brownlee Precision Model 440 incorporates ... circuitry in a friendly easy-to-use instrument. Each ... amplifier, an 8-pole Bessel lowpass filter, a ... output offset controls. A control knob sets ...
... versatile & modular instrument which can be used ... Extracellular, Transducer & Multi-channel Isolated Amplification ... Supply unit (NL900D) forms the heart of every ... by this unit, but wiring within the case ...
Rat Epidermal Keratinocytes (REK) (>500,000 cells)...
... The Brownlee Precision Model 410 is a ... used to amplify small signals from sources which ... frequency noise. Each channel consists of a high ... 2-pole lowpass filter, and an output offset control. ...
Biology Products: