Navigation Links
Non-slip tracheal implants
Date:7/9/2012

funded by the German Federal Ministry of Education and Research BMBF.

Bioactive coatings lower the risk for patients

The scientists used stents lined with a polyurethane (PU) film, which were produced by Aachen-based Leufen Medical GmbH. In the ensuing tests, a wide variety of different coatings were applied to the PU film: In addition to synthetic polymers composed of organic acids, the researchers also tried out biological proteins such as fibronectin and type-I collagen. The coating was modified again using plasma technology, with vacuum-ionized gas being used to treat the surface. The experts used an untreated PU film for control purposes. "In order to find out which of the surface coatings was the most suitable, we brought both lab-cultivated cell lines and human primary tracheal epithelial cells into contact with the films in cell culture vessels. What we wanted, of course, was for the primary respiratory cells from human tissue to attach themselves to the film," explains Hampel. The researchers achieved their best results with the protein-coated film, on which the primary tracheal epithelial cells grew particularly well and multiplied. "The respiratory cells proved to be more vital on bioactive films rather than on ones treated with plasma. By contrast, polymer-coated film turned out to be completely useless," says Hampel.

The laboratory tests have since been completed, and animal tests are in preparation. If the good lab results are confirmed in these tests, the next step will be to conduct clinical trials of the modified stents at the Schillerhhe specialist lung clinic, part of the Robert Bosch Hospital. "We hope that, within just a few years, our well-tolerated, cell-compatible surface coatings will be used for other biomedical prostheses such as pacemaker leads, tooth implants and replacement joints," says Hampel.


'/>"/>
Contact: Dr. Martina Hampel
Martina.Hampel@igb.fraunhofer.de
49-711-970-4083
Fraunhofer-Gesellschaft
Source:Eurekalert  

Page: 1 2

Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Non-slip tracheal implants
(Date:9/15/2014)... One of Australia,s leading coral reef ecologists fears that ... for ecosystem survival that we once thought. , In ... the ARC Centre of Excellence for Coral Reef Studies ... the most important species within reef ecosystems. , In ... are vital jobs that keep the ecosystem safe and ...
(Date:9/15/2014)... professor in the Department of Science and Technology in ... Sciences at Virginia Tech, has won a 2014 National ... the prospects and problems of creating a global nuclear ... Fukushima I Nuclear Power Plant in March 2011 was ... nuclear emergencies, Schmid said. Three of the plant,s six ...
(Date:9/15/2014)... of the cheetah: The big predator is the fastest land ... just a few seconds. As it ramps up to top ... it reaches a full gallop. , Now MIT researchers have ... a robotic cheetah a sleek, four-legged assemblage of gears, ... its feline counterpart. The team recently took the robot for ...
Breaking Biology News(10 mins):Specialized species critical for reefs 2'Nuclear disasters don't respect national boundaries' 2Run, cheetah, run 2Run, cheetah, run 3
... of climate change on the microbial communities of two ... in Alaska, a University of Oklahoma research group has ... According to Jizhong Zhou, OU professor of botany ... Genomics, the results of these studies could potentially contribute ...
... WORCESTER, Mass. Researchers at the University of Massachusetts Medical ... which is implicated in 20 percent of inherited cases of ... a part in sporadic forms of the disease. Discovery of ... edition of Nature Neuroscience . While the SOD1 ...
... 18 October 2010, Singapore A total of 15 world ... in their respective fields at the 6th Decade of the ... 20 October 2010. Jointly organised by A*STAR,s Institute of ... (DRTech) and NUS,s Temasek Laboratories, it is the first such ...
Cached Biology News:UMMS researchers identify protein associated with sporadic ALS 2UMMS researchers identify protein associated with sporadic ALS 3Singapore hosts first 'Decade of the Mind' conference in Asia 2Singapore hosts first 'Decade of the Mind' conference in Asia 3
(Date:9/15/2014)... of fibers made of carbon nanotubes is neat, but Rice ... single-walled carbon nanotubes in new fibers created at Rice line ... designed by chemist Angel Mart and his colleagues. , The ... this month in the journal ACS Nano , is ... into a fiber. , Left to their own devices, carbon ...
(Date:9/15/2014)... Sept. 15, 2014  iVinci Health LLC, the company ... Revenue Management system, branded as VisitPay®, has successfully closed ... the launch of a new extension to VisitPay® – ... easy and convenient way for patients to manage their ... by them and their families. The new ...
(Date:9/15/2014)... 2014 Die zweite jährliche International ... bis 18. Oktober stattfinden. Die IPAW ist eine ... (PPTA) und ihrer Mitgliedsunternehmen und ... Bewusstsein für die Gewinnung von Quellplasma zu steigern ... und Verbessern von Leben zu würdigen , ...
(Date:9/15/2014)... September 15, 2014 Hydro Dynamics, ... announced today that it will be partnering with ... ( http://www.proteaf.com ) for implementing its Shock Wave ... continuous processing. Continuous flow chemistry through process ... pharmaceutical and petrochemical markets for decades. The ...
Breaking Biology Technology:Rice rolls 'neat' nanotube fibers 2Rice rolls 'neat' nanotube fibers 3iVinci Health Raises $5M to Fuel National Expansion, Announces Launch of Personal Finance Portal for Healthcare 2iVinci Health Raises $5M to Fuel National Expansion, Announces Launch of Personal Finance Portal for Healthcare 3International Plasma Awareness Week feiert Spender und rückt seltene Krankheiten in den Mittelpunkt 2International Plasma Awareness Week feiert Spender und rückt seltene Krankheiten in den Mittelpunkt 3Hydro Dynamics Partners with the Continuous Flow Chemistry Experts of Proteaf Technologies 2
... is,strengthening its customer-focused biomarker services portfolio to,pharmaceutical, ... Xie will lead those efforts as Battelle,s ... a suite of biomarker services, including biomarker,discovery, ... clients,better define molecular mechanisms of diseases, toxicity, ...
... against management - with six million, votes revoked ... change rules, TORONTO, June 25 /PRNewswire/ - The ... be in court today and will seek a,declaration that ... Meeting,was illegally held and will request that a proper ...
... probiotic ingredient, GanedenBC30, to power new raisin bran probiotic muffins. ... ... Main Street Gourmet, one of the fastest growing manufacturers of gourmet ... muffin fortified with the high-survivability probiotic, GanedenBC30 (Bacillus coagulans ...
Cached Biology Technology:Battelle Selects Xie to Develop Biomarker Services 2Main Street Gourmet Launches New Probiotic Muffins 2Main Street Gourmet Launches New Probiotic Muffins 3
... for Optimal Microdissection , CapSure HS and ... and rapid extraction of populations of pure ... with Laser Capture Microdissection., Ensure the ... Analysis , All CapSure LCM Caps have ...
... , CapSure HS and CapSure Macro LCM ... of populations of pure cells from tissue ... Microdissection., Ensure the Integrity of Microdissected ... CapSure LCM Caps have a patented transfer ...
... detector is an optical unit that can ... or Dyad Disciple gradient-capable thermal cycler (purchased ... photonics shuttle that contains four LEDs for ... nm, 620-650 nm) and two filtered photodiodes ...
... Capture Microdissection (LCM) is the method of ... Microdissection is the only instrument to offer ... flexibility., UV Laser Cutting ... non-soft tissues and capturing large numbers of ...
Biology Products: