Navigation Links
Non-coding DNA implicated in type 2 diabetes
Date:1/12/2014

mmed to behave differently in people with type 2 diabetes," said co-author Mark McCarthy, a Wellcome Trust Senior Investigator at the University of Oxford. "This study provides some important clues to the mechanisms which are disturbed in the earliest stages of the development of type 2 diabetes, and may point the way to novel ways of treating and preventing the disease."

The team identified genome sequences that drive gene activity in insulin-producing cells specifically. They found that these sequences are located in clusters, and that genetic variants known to be linked to diabetes risk are also found in these clusters.

"Many people have small DNA variants in such regulatory elements, and these variants affect gene expression in the cells that produce insulin. This knowledge will allow us to understand the detailed mechanisms whereby specific DNA variants predispose to diabetes," said Professor Ferrer.


'/>"/>

Contact: Sam Wong
sam.wong@imperial.ac.uk
44-207-594-2198
Imperial College London
Source:Eurekalert

Page: 1 2

Related biology news :

1. Garvan Institute receives grant to research role of long non-coding RNAs in Parkinsons disease
2. A hallmark for the development of testicular tumors found in the aberrant regulation of small non-coding RNA
3. Immune system implicated in prematurity complication
4. Protein involved in nerve-cell migration implicated in spread of brain cancer
5. BROCA sequencing approach evaluates all 24 genes implicated in breast cancer
6. Diabetes Research Institute develops oxygen-generating biomaterial
7. New study shines light on barriers to diabetes care in NYC Bangladeshi community
8. Commonly used diabetes drug may help to prevent primary liver cancer
9. Approach to diabetes self-management too narrow, study suggests
10. Gut microbiota transplantation may prevent development of diabetes and fatty liver disease
11. From feast to famine: A metabolic switch that may help diabetes treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... 30, 2014) People who suffer from asthma may ... control their asthma besides properly taking medications and avoiding ... in the Annals of Allergy, Asthma and Immunology ... Allergy, Asthma and Immunology (ACAAI), asthma sufferers can learn ... The woman described in the Annals article improved her ...
(Date:9/29/2014)... Monday, September 29: Between 1970 and 2010 populations ... the globe dropped 52 percent, says the 2014 ... Fund (WWF). This biodiversity loss occurs disproportionately in ... of high-income countries. , In addition to the ... point to other warning signs about the overall ...
(Date:9/29/2014)... In order to support the world,s needs ... polymers and more, new and more efficient catalytic ... of researchers, including several from Wayne State University, ... a new grant from the National Science Foundation. ... Design of Multicomponent Materials for Electrocatalytic Cascade Reactions," ...
Breaking Biology News(10 mins):Asthma symptoms kicking up? Check your exposure to air pollution 2Half of global wildlife lost, says new WWF report 2Wayne State research aims to develop new, more efficient catalytic materials 2
... boost our understanding of the fragile marine environment, the ... for Environment, Fisheries & Aquaculture Science (Cefas) are launching ... existing collaboration between the two institutions and establish exciting ... climate change on the marine environment will influence much ...
... science concern the behaviour of the most commonplace compound ... the mysteries are now being unravelled by the latest ... was presented at a recent conference organised by the ... and other compounds at the molecular level. , Some ...
... window into the Earths mantle, a University of Houston professor ... more complex than previously thought. Jonathan Snow, ... researchers in a North Pole expedition, resulting in a discovery ... layer that lies beneath the planets outer crust. These ...
Cached Biology News:New UEA-Cefas alliance launched 2ESF conference probes water's mysterious interactions at molecular level 2ESF conference probes water's mysterious interactions at molecular level 3Journey to the center of the earth: Discovery sheds light on mantle formation 2Journey to the center of the earth: Discovery sheds light on mantle formation 3
(Date:9/30/2014)... Applying a well-known optical phenomenon called thin-film ... has demonstrated the ability to "paint" ultra-thin coatings ... promise for making future, flexible electronic devices, creating ... next-gen rocket ships and spacecraft with extremely lightweight ... in water, it becomes iridescent, revealing a myriad ...
(Date:9/30/2014)... YORK , Sept. 30, 2014 ... and segments with highest potential revenues Do you ... updated report gives you revenue predictions for those ... For those therapies you find financial data, R&D ... analysis you get sales forecasts to 2024 at ...
(Date:9/30/2014)... Proove Biosciences , the commercial and research leader in ... test built upon research from their published P.A.I.N. Study. ... physicians with an objective way to understand theirs patient’s ... individuals. With this new test, physicians will be able ... that will affect their pain tolerance. , The P.A.I.N. ...
(Date:9/30/2014)... , September 30, 2014 ... intuitive browsing of chemistry in documents ... software solutions and consulting services for life science ... information and generate Markush structures from documents. ... organizations intellectual property, however generating and understanding Markush ...
Breaking Biology Technology:Taking thin films to the extreme 2Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 2Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 3Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 4Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 5Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 2Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 3ChemAxon Introduces ChemCurator for Chemical Information Extraction and Markush Structure Creation 2
... RedPrairie Corp. , the Waukesha-based manufacturer of supply chain ... a recent user conference. , ,At RedShift: 2006, the ... unveiled its E2e suite of solutions, which is described ... chain challenges faced by customers. , ,RedPrairie executive John ...
... - By several measures, these should be heady days ... manufacturing jobs were lost, the economy is back, manufacturing revenue ... there is a sense of unease linked to withering competitive ... of what their American counterparts earn, where manufacturers have a ...
... that the ownership of a patent right initially goes to ... in the workplace? The company? The inventing employee? It depends ... Is there an employment agreement signed by the employee that ... workplace to the company? , ,No? Then you must ask: ...
Cached Biology Technology:Manufacturers advised to redesign customer relations 2Manufacturers advised to redesign customer relations 3Who owns what invention in the workplace? 2
... (MOPS Buffered) has been developed specifically for ... solution. HRP Stabilizer prevents the loss ... of the antibody or protein antigen portion ... at 0.2 microns., ,Contents: Aqueous, protein-containing ...
384 Well PCR Plate Carrier for Thermo-Sealer...
... strength adhesive system which facilitates the easy removal ... either side of the frame are of differing ... has an easy release adhesive whereas the reverse, ... bond. This means that when the coverslip is ...
These 18x18 square No.1 Corning cover glasses are made from No. 0211 zinc titania glass and are 0.16 to 0.19mm thick....
Biology Products: