Navigation Links
Noise down, neuron signals up
Date:8/15/2012

Biomedical engineer Muhammet Uzuntarla from Bulent Ecevit University, Turkey, and his colleagues present a biologically accurate model of the underlying noise which is present in the nervous system. The article is about to be published in EPJ B. This work has implications for explaining how noise, modulated by unreliable synaptic transmission, induces a delay in the response of neurons to external stimuli as part of the neurons coding mechanism.

Neurons communicate by means of electrical pulses, called spikes, exchanged via synapses. The time it takes for brain cells to first respond to an external stimulus with an electric signal commonly referred to as fist-spike latencyis of particular interest for scientists. It is thought to carry much more neural information than subsequent serial spike signals.

The authors analysed the presence of noise in the nervous system detected through changes in first-spike latency. The noise is due to the synaptic bombardment of each neuron by a large number of incoming excitatory and inhibitory spike inputs. Previous attempts at noise modeling used a generic bell-shaped signal, referred to as a Gaussian approximation. Now, Uzuntarla and his colleagues have devised a noise model that is closer to the biological reality.

They showed there is a relation between the noise and delays in spike signal transmission. The latter is caused by unreliable synapses that do not always transmit the signal, because their chemical-based signalling does not always work. Yet, the authors also demonstrated that synaptic unreliability can be controlled.

To do so, they identified two factors that could be tuned influencing the noise, namely the incoming excitatory and inhibitory input signalling regime and the coupling strength between inhibitory and excitatory synapses. Ultimately, the authors concluded, modulating these factors could help neurons encode information more accurately.


'/>"/>

Contact: Janine Haubenreisser
janine.haubenreisser@springer.com
49-622-148-78414
Springer
Source:Eurekalert

Page: 1

Related biology news :

1. Not just for the birds: Man-made noise has ripple effects on plants, too
2. Unexpected discovery reveals a new mechanism for how the cerebellum extracts signal from noise
3. Human noise has ripple effects on plants
4. ONR taps research teams to help reduce jet noise
5. Researchers have identified a gene with a key role in neuronal survival
6. Glycogen accumulation in neurons causes brain damage and shortens the lives of flies and mice
7. Simple mathematcal pattern describes shape of neuron jungle
8. Ion selectivity in neuronal signaling channels evolved twice in animals
9. Deterring signals: Tobacco plants advertise their defensive readiness to attacking leafhoppers
10. Bacterium signals plant to open up and let friends in
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... West Orange, NJ. April 16, 2014. Kessler Foundation ... for $1.8 million from the Department of Defense ... PhD, is principal investigator for the randomized, double-blinded, ... to improve bone and muscle strength after spinal ... Human Performance & Engineering Research at Kessler Foundation. ...
(Date:4/17/2014)... developed at Sandia National Laboratories and recently licensed to ... cheaper. , Bacillus anthracis , the bacteria ... over the world and can cause serious, and often ... can survive in harsh conditions for decades. In humans, ... skin contact, inhalation of spores or eating contaminated meat. ...
(Date:4/17/2014)... KAN. A Kansas State University engineer has ... and remotely detects improvised explosive devices. The same ... William Dunn, the Steven M. and Kay L. ... mechanical and nuclear engineering, and his research team ... hidden underground or in car trunks. The distance ...
Breaking Biology News(10 mins):Kessler Foundation awarded Department of Defense grant for spinal cord injury research 2Pocket-sized anthrax detector aids global agriculture 2Pocket-sized anthrax detector aids global agriculture 3Patented research remotely detects nitrogen-rich explosives 2
... their way, cheetahs, lions, elephants, camels and other large wild ... "If we only have 10 minutes to present this idea, ... and evolutionary biology at Cornell. "But if people hear the ... much as we have. Right now, we are investing all ...
... A team of engineers from Washington University in St. ... removed bioaerosols -- airborne biological particulate matter -- from ... new generation of hybrid filters. , The bioaerosols identified ... lifeguards who had become ill with hypersensitivity pneumonitis, a ...
... a defensive, protective reaction. This ancestral and automatic behavior ... predator. A new study published in Psychophysiology finds that ... a threat. The mere picture of an injured or ... images, the study's participants froze as their heart rate ...
Cached Biology News:Proposal would allow wild animals to roam North America 2Proposal would allow wild animals to roam North America 3Device traps, disables harmful bacteria 2When in danger humans are similar to a deer in the headlights 2
(Date:1/14/2014)... pet owners drew up their lists of New Year,s resolutions for ... of my furry companion." Nowadays there are pet salons, dog and ... take the little canine or feline darlings along wherever mommy or ... pricey toys at the pet store. But anyone who has ever ...
(Date:1/14/2014)... MA (PRWEB) January 14, 2014 iLab Solutions, ... Detwiler as the new Director of Product Strategy. In this ... well as iLab sub-teams to guide in the development of ... iLab provides the maximum possible benefit to the scientific community ...
(Date:1/14/2014)...   Kinaxis ®, provider of RapidResponse ®, a cloud-based ... planning ( S&OP ) service, is proud to be a ... be held at the Hilton San Diego Bayfront, January 30 ... Elisabeth Kaszas , Director of Supply Chain at Amgen, as ...
(Date:1/14/2014)... Independent publisher Bitingduck Press, with offices in Altadena ... ideas for 2014 in production and sales of interactive ... high-quality, low-cost, DRM-free ebooks and to use the sales ... first major development will be bookstore sales in local ...
Breaking Biology Technology:New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2Event Alert: Kinaxis Customer to Present at the Biomanufacturing Summit "Supply Chain: Improving Network Effectiveness" 2Bitingduck Press Looks Forward to 2014 With Multimedia E-books 2
... the US dental biomaterials market will rebound to reach ... Research GroupWALTHAM, Mass., March 24 According to Millennium ... 2009 report, although dental biomaterials are being used ... market for these products will be dampened by the ...
... Byetta LAR Will Earn Decision Resources, Clinical Gold ... According to a New Report from Decision ResourcesWALTHAM, ... the world,s leading research and advisory firms for ... indicate that a therapy,s effect on glycosylated hemoglobin ...
... first metallic needle AFM probes are now available from Nanoscience ... and high conductivity, metallic needle probes are enabling new applications ... ... Phoenix, AZ (PRWEB) March 24, 2009 -- Nanoscience Instruments, ...
Cached Biology Technology:How Long Will the Economic Downturn Affect the Dental Biomaterials Market? 2Surveyed Experts Indicate That Byetta LAR and Victoza Have Advantages Over Actos in the Treatment of Type 2 Diabetes 2Surveyed Experts Indicate That Byetta LAR and Victoza Have Advantages Over Actos in the Treatment of Type 2 Diabetes 3Nanoscience Instruments, Inc. Announces Distribution of NaugaNeedles Metallic Needle AFM Tips 2
... SBED Protein:Protein Interaction Reagent A powerful ... rapidly gained traction as an in vitro ... number of publications feature the exclusive Pierce ... study a variety of issues relating to ...
... Incubator is a compact benchtop and ... microprocessor controller with a large display ... agitation speed. Air circulation inside to ... Temperature can be easily calibrated from ...
... fast emerging as a powerful new tool ... now, only amino groups have been able ... such as our Sulfo-SBED. Sulfhydryl-reactive Mts-Atf-Biotin and ... additions to the protein interaction tool chest ...
... MULTI-FUN Incubator is a compact benchtop ... a microprocessor controller with a large ... and agitation speed. Air circulation inside ... incubator. Temperature can be easily calibrated ...
Biology Products: