Navigation Links
Nobel laureate Dr. Linda Buck elected to American Academy of Arts & Sciences 2008 Class of Fellows
Date:4/29/2008

SEATTLE Nobel laureate Linda Buck, Ph.D., member of the Basic Sciences Division at Fred Hutchinson Cancer Research Center, has been elected to membership in the American Academy of Arts & Sciences, or AAAS, one of the nations oldest and most prestigious honorary societies and independent policy-research centers. She is among 190 new fellows and 22 foreign honorary members to join the AAAS 2008 class of fellows. Drawn from the sciences, the arts and humanities, public affairs and the nonprofit sector, AAAS fellows are leaders in their fields. This years class includes Nobel laureates, recipients of Pulitzer and Pritzker prizes, Academy and Grammy awards and Kennedy Center honors. The latest honorees include blues guitarist B.B. King, filmmakers Ethan and Joel Cohen, and astronomer Adam Riess, who contributed to the discovery of dark energy in the universe. (Please see below for link to AAAS news release and complete list of winners.)

Buck in 2004 received the Nobel Prize in physiology or medicine for her groundbreaking work on odorant receptors and the organization of the olfactory system the network responsible for our sense of smell. She shared the honor with Richard Axel, Ph.D., of Columbia University.

Buck, who joined the Hutchinson Center faculty in 2002 after 11 years as a faculty member at Harvard Medical School, is the fifth Hutchinson Center researcher to be elected for AAAS membership.

She was a senior postdoctoral researcher in Axels laboratory when she disclosed the nature of the olfactory receptors, and they co-published this work in 1991. Their work is the first to define one of our sensory systems in the most detailed manner possible by defining the genes and proteins that control this remarkably complex response. This was a landmark achievement in the study of the nervous system.

The basic principles for recognizing and remembering about 10,000 different odors have long been a mystery. In a series of pioneering studies, Buck clarified how our olfactory system works. She discovered a large gene family, made up of some 1,000 different genes that give rise to an equivalent number of olfactory-receptor types. These receptors are located on the olfactory receptor cells, which occupy a small area in the upper part of the lining of the nose and detect the inhaled odorant molecules.

Buck and Axel showed that every single olfactory-receptor cell produces one and only one of the odorant receptor genes. Thus, there are as many types of olfactory- receptor cells as there are odorant receptors.

Most odors are composed of multiple odorant molecules. Buck discovered that each odorant molecule activates several different odorant receptors and each odorant receptor can recognize multiple odorants, but that different odorants even closely related ones activate different combinations of receptors. This leads to a combinatorial code forming an "odorant pattern" somewhat like the colors in a patchwork quilt or in a mosaic. This is the basis for our ability to recognize and form memories of approximately 10,000 different odors, as well as our ability to distinguish odorants with nearly identical chemical structures as having different smells.

Buck has also discovered and characterized families of receptors for pheromones and tastes, providing insights into the mechanisms underlying pheromone effects and taste perception.

Buck, also a Howard Hughes Medical Institute Investigator and an affiliate professor in the Department of Physiology and Biophysics at the University of Washington, is the recipient of many national and international scientific awards. In 2003 she received the Gairdner Award, the Perl-UNC Neuroscience Prize and was elected a member of the National Academy of Sciences. Shes also the recipient of the Unilever Science Award, the LVMH Moet Hennessy Louis Vuitton Science for Art Prize, the R.H. Wright Award in Olfactory Research and the Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research.


'/>"/>

Contact: Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center
Source:Eurekalert

Related biology news :

1. Gene-targeting pioneer Mario Capecchi shares 2007 Nobel Prize in Medicine
2. Professor Sir Martin Evans wins Nobel Prize for Medicine
3. Nobel Peace Prize 2007 to intergovernmental panel on climate change
4. Neilson member of Nobel Prize-winning panel of scientists
5. IOS Press congratulates IPCC with Nobel Peace Prize
6. Life-saving clean water project secures $13M from Bill & Melinda Gates Foundation
7. 3 Columbia University Medical Center faculty elected to Institute of Medicine
8. Synaptics SecurePad(TM) Selected as CES Innovations 2008 Design and Engineering Award Honoree
9. Rwandas Gishwati Forest selected as site for historic conservation project
10. 19 researchers selected as 2008 Leopold Leadership Fellows
11. Motorola Biometric Identification System Selected by West Virginia State Police
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/18/2016)... , Jan. 18, 2016  Extenua Inc., ... that simplifies the use and access of ubiquitous ... go-to-market partnership with American Cyber.  ... extensive experience leading transformational C4ISR and Cyber initiatives ... integrating the latest proven technology solutions," said ...
(Date:1/13/2016)... , January 13, 2016 ... the addition of the  "India Biometrics ... & Forecast (2015-2020)"  report to ... ) has announced the addition of ... Market - Estimation & Forecast (2015-2020)" ...
(Date:1/8/2016)... and MANCHESTER, United Kingdom , Jan. ... developer of innovative sensor-based diagnostic products, today announced the closing ... new and existing investors.  Proceeds from the financing will be ... , a hand-held device for detecting early-stage pressure ulcers. ... Ireland after receiving CE Mark approval. The device,s ...
Breaking Biology News(10 mins):
(Date:2/10/2016)... , February 10, 2016 Early-career researchers ... , Peru , Uganda and ... life-enhancing work in health and nutrition   Indonesia ... Uganda and Yemen are being ... and epidemiology. They are also celebrated for mentoring young women scientists who ...
(Date:2/10/2016)... is introducing a hybrid membership model which will provide ... joining or renewing through an organizational purchasing model. For ... employee in any size association or AMC office can ... benefits.   John H. Graham, IV , ... organizations of any size and their employees to gain ...
(Date:2/10/2016)... plc (NYSE: AGN ) a leading global pharmaceutical ... CEO and President, will be featured as the keynote ... Capital Markets Healthcare Conference on Tuesday, February 23, 2016 ... Hotel in New York, NY . ... accessed on Allergan,s Investor Relations web site at ...
(Date:2/10/2016)... MO (PRWEB) , ... February 10, 2016 , ... ... will attend the International Society of Pharmaceutical Engineering (ISPE) Rocky Mountain Chapter 21st ... ISPE is expecting to fill more than 100 tables for its annual event, ...
Breaking Biology Technology: