Navigation Links
'No muss, no fuss' miniaturized analysis for complex samples developed
Date:11/18/2009

a buffer solution under controlled pressure in the opposite direction. This opposing pressure flow acts as a "fluid gate" between the sample reservoir and the microchannel. Gradually reducing the pressure of the counterflow opens the "gate" a little bit at a time. A specific sample component is detected when the pressure flow becomes weak enoughwhen the "gate" opens wide enoughthat the component's electrophoretic motion pushes it against the pressure flow and into the channel for detection. In this way, different components enter the channel at different times based on their particular electrophoretic motion. Most importantly, the channel doesn't become fouled because the unwanted material in the sample is held out during the analysis by the pressure flow.

In their paper, the researchers validated their GEMBE analysis technique by testing it with solutions of whole milk, dirt, estuarine sediment, coal fly ash, pulverized leaves and blood serum. In all casesand without the muss and fuss of pre-analysis sample preparationthe system was able to reproducibly separate and quantify specific components from the solutions, including potassium, calcium, sodium, magnesium, lithium and melamine.

"GEMBE is well-suited to the microfluidic analysis of 'real-world' samples," Strychalski says. "We have shown that the method can handle solutions containing particulates, proteins and other materials that would confound the majority of other microfluidic techniques."

Because of its ability to easily and rapidly characterize complex mixtures with minimal preparation, the researchers believe that GEMBE shows enormous promise for diverse applications, such as monitoring contaminants in food or water supplies, determining nutrient levels in soil, detecting biochemical warfare agents, and diagnosing medical conditions. The next steps, they say, are to miniaturize the desktop equipment now used in the system and integrate all of the parts to develop a true "lab-on
'/>"/>

Contact: Michael E. Newman
michael.newman@nist.gov
301-975-3025
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Micro microwave does pinpoint cooking for miniaturized labs
2. Ginkgo SRMs: Tools for product analysis/quality
3. DNA analysis shows true dispersal of protozoa
4. Interacting protein theory awaits test from new neutron analysis tools
5. Analysis of breast and colon cancer genes finds many areas of differences between tumors
6. Tumor genome analysis unveils new insights into lung cancer
7. Powerful integration of lipid metabolic profiling with gene expression analysis
8. Human clones: New U.N. analysis lays out worlds choices
9. More comprehensive analysis of Klamath River basin needed to aid decision makers
10. Analysis calls for medical device information to better serve patients and doctors
11. Avian origins: new analysis confirms ancient beginnings
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
'No muss, no fuss' miniaturized analysis for complex samples developed
(Date:10/2/2014)... -- CARTES SECURE CONNEXIONS 2014 Conference: A Step ... CARTES SECURE CONNEXIONS 2014 is being held at Paris ... 2014. This 29 th  international meeting for the digital ... bring together the global community of a constantly evolving ... conferences will set the pace for the event.   ...
(Date:10/1/2014)... October 1, 2014 ... der Biowissenschaften   Die Biowissenschaften erlebten ... Gehen zahlreicher Detektionstechnologien. Einige davon sind Senkrechtstarter ... Die Photonen-Upconversion ist eine neuartige Detektionstechnologie, die ... Begeisterung aufgenommen wurde. Jetzt ist diese Technologie ...
(Date:9/30/2014)... is published today in the first authoritative scientific study ... on both sides of the grouse moor management debate. ... the Ecohydrology of River basins) project has shown that ... support red grouse populations for gun sports, has significant ... properties, river water chemistry and river ecology. , A ...
Breaking Biology News(10 mins):CARTES SECURE CONNEXIONS - Conferences & Speakers 2014 2CARTES SECURE CONNEXIONS - Conferences & Speakers 2014 3CARTES SECURE CONNEXIONS - Conferences & Speakers 2014 4Innovative Verwendungslösung für die Photonen-Upconversion 2Innovative Verwendungslösung für die Photonen-Upconversion 3Grouse moor burning causes widespread environmental changes 2
... the Veterans Affairs Iowa City Health Care System have uncovered ... multidisciplinary team of scientists pieced together information from clinical observations ... knowledge from modern genetics and molecular biology to show that ... drop in pH (increased acid) in a way that shuts ...
... the first time paleontologists have found fossilized burrows of tetrapods ... in Antarctica dating from the Early Triassic epoch, about ... fine sand from an overflowing river poured into the animals, ... largest preserved piece is about 14 inches long, 6 inches ...
... 6 Communication,Intelligence Corporation (the "Company") (OTC Bulletin ... for business process,automation in the financial industry and ... that it has closed a financing, on,June 5, ... "Investor")., As part of the financing, the ...
Cached Biology News:Study identifies brain pathway that shuts down seizures 2Study identifies brain pathway that shuts down seizures 3Scientists find 245 million-year-old burrows of land vertebrates in Antarctica 2Communication Intelligence Corporation Closes $3.6 Million Financing 2Communication Intelligence Corporation Closes $3.6 Million Financing 3Communication Intelligence Corporation Closes $3.6 Million Financing 4
(Date:10/2/2014)... Switzerland and Morgantown, West Virginia (PRWEB) October 02, ... (OTCQB: PRGB ) and InSphero AG jointly announced ... mass spectrometry imaging of InSphero’s 3D InSight™ microtissues. ... and hosted members of InSphero’s scientific team for ... the microtissues. Protea has since developed workflows for ...
(Date:10/2/2014)... 2014 Laborie Medical Technologies, Inc. ("LABORIE"), con ... completado la adquisición de Unisensor AG y Unisensor ... central sita en Wiesendangen, Suiza, y lleva a cabo ... Hampshire . Unisensor está especializada en el desarrollo ... evaluar la presión y valores de pH para los ...
(Date:10/2/2014)... SAN CARLOS, Calif. and ... Intrexon Corporation (NYSE: XON) , a leader in ... the seventh largest generic drug manufacturer by volume ... a second Exclusive Channel Collaboration (ECC) for a ... microbial-based expression system, the goal of the collaboration ...
(Date:10/1/2014)... METTLER TOLEDO’s newly improved XS balance line includes ... well as a dual range microbalance . As ... weighing pan delivers results up to twice as fast, ... design details mean users no longer need to suffer ... in front of the balance. Barbara Bienlein, medical specialist ...
Breaking Biology Technology:Protea Biosciences and InSphero AG Successful in Mass Spectrometry Imaging of 3D Microtissues 2Protea Biosciences and InSphero AG Successful in Mass Spectrometry Imaging of 3D Microtissues 3Protea Biosciences and InSphero AG Successful in Mass Spectrometry Imaging of 3D Microtissues 4LABORIE adquiere Unisensor AG y Unisensor USA, Inc. 2Intrexon and Amneal Expand Relationship with Second Product Collaboration 2Intrexon and Amneal Expand Relationship with Second Product Collaboration 3METTLER TOLEDO’s XS Balance Line Delivers Performance and Ergonomics To Safeguard Health in the Workplace 2METTLER TOLEDO’s XS Balance Line Delivers Performance and Ergonomics To Safeguard Health in the Workplace 3
... from a 15-day tour of some of Australia and New ... companies because unlike in the States, where the Web 2.0 ... hasnt been captivated by the same frenzy. Indeed, of the ... the major tech venues of the region, only two companies ...
... InvivoSciences LLC , a startup biotechnology firm with ... bridge the gap between molecular and animal testing methods. ... maladies, Invivo's manufactured live tissue system could provide that ... company - featured at a recent meeting of the ...
... Wis. - Mayor Mary Jo Carson is thrilled about ... , ,Located in the geographic center of the state, Wisconsin ... and tax base, but this new project could be the ... the proposed 40 to 60 million gallon annual production facility ...
Cached Biology Technology:Start-ups "down under" not captivated by Web 2.0 2Start-ups "down under" not captivated by Web 2.0 3Biotech firm uses live heart tissue in drug screens 2Biotech firm uses live heart tissue in drug screens 3Wisconsin Rapids to welcome new ethanol plant 2
... Klenow fragment is a ... coli DNA Polymerase I ... -> 5 exonuclease activity, but ... activity. Klenow retains the polymerization ...
... RNase H degrades, as an ... DNA hybrids of natural origin, ... of synthetic complexes, e.g. poly(A) x ... 5-phosphate and 3-OH termini. Nearly no ...
... overproducing clone of T4 DNA Ligase. Description: T4 ... bond between juxtaposed 5' phosphoryl and 3'-hydroxyl ... single-stranded nicks in duplex DNA, RNA or DNA/RNA ... fragments of duplex DNA or RNA (1) . ...
Goat polyclonal to Haptoglobin ( Abpromise for all tested applications). Antigen: Affinity purified human haptoglobin. Entrez GeneID: 3240 Swiss Protein ID: P00738...
Biology Products: