Navigation Links
No 2 people smell the same
Date:12/13/2013

DURHAM, NC -- A difference at the smallest level of DNA -- one amino acid on one gene -- can determine whether you find a given smell pleasant. A different amino acid on the same gene in your friend's body could mean he finds the same odor offensive, according to researchers at Duke University.

There are about 400 genes coding for the receptors in our noses, and according to the 1000 Genomes Project, there are more than 900,000 variations of those genes. These receptors control the sensors that determine how we smell odors. A given odor will activate a suite of receptors in the nose, creating a specific signal for the brain.

But the receptors don't work the same for all of us, said Hiroaki Matsunami, Ph.D., associate professor of molecular genetics and microbiology at the Duke University School of Medicine. In fact, when comparing the receptors in any two people, they should be about 30 percent different, said Matsunami, who is also a member of the Neurobiology Graduate Program and the Duke Institute for Brain Sciences.

"There are many cases when you say you like the way something smells and other people don't. That's very common," Matsunami said. But what the researchers found is that no two people smell things the same way. "We found that individuals can be very different at the receptor levels, meaning that when we smell something, the receptors that are activated can be very different (from one person to the next) depending on your genome."

The study didn't look at the promoter regions of the genes, which are highly variable, or gene copy number variation, which is very high in odor receptors, so the 30 percent figure for the difference between individuals is probably conservative, Matsunami said.

While researchers had earlier identified the genes that encode for odor receptors, it has been a mystery how the receptors are activated, Matsunami said. To determine what turns the receptors on, his team cloned
'/>"/>

Contact: Karl Leif Bates
karl.bates@duke.edu
919-681-8054
Duke University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Teaching about hearing can save young peoples ears
2. Study finds peoples niceness may reside in their genes
3. Southampton researchers lead 2 international projects to help people out of poverty
4. Why do people choke when the stakes are high?
5. 5-limbed brittle stars move bilaterally, like people
6. Understanding why some people have propensity to disease
7. New video series highlights the people who fuel Americas innovation pipeline
8. Tigers take the night shift to coexist with people
9. Can videogaming benefit young people with autism spectrum disorder?
10. Your body doesnt lie: People ignore political ads of candidates they oppose
11. How silver turns people blue
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
No 2 people smell the same
(Date:9/18/2014)... system that can operate inside the bore of an ... a biomedical research partnership program at Brigham and Women,s ... the robot, in conjunction with real-time MRI images, can ... and less discomforting for the patient. The novel system ... with greater precision. , Developed by a team of ...
(Date:9/18/2014)... No matter how many times it,s demonstrated, ... communicating creatures. , But by using a ... radically alter their behavior to suit their population. ... them are present, and act accordingly. , Once ... it may change from innocuous to pathogenic, or ...
(Date:9/18/2014)... stored in DNA, tiny strands of nucleic acid that ... express this genetic data, our DNA is copied into ... that perform tasks in our cells. , Several ... molecule. Unlike all other known RNAs, this molecule is ... are abundant, little has been known about how they ...
Breaking Biology News(10 mins):Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 2Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 3Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 4Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 5Researchers study vital 'on/off switches' that control when bacteria turn deadly 2Researchers study vital 'on/off switches' that control when bacteria turn deadly 3Scientists find how mysterious 'circular RNA' is formed, claim muscular dystrophy link 2
... (SALT LAKE CITY)Alternating hemiplegia of childhood (AHC) is a ... episodes of paralysis and stiffness, first affecting one side ... and disappear, again and again, and affected children often ... older, children fall progressively behind their peers in both ...
... smog-filled sky or a contaminated river, according to a ... for the prosperous. People living in China,s cities ... more likely to begreen: re-using their plastic grocery bags ... the international journal AMBIO , indicates that the ...
... doesn,t mean making a trip to the local pharmacy for ... the forest to provide a pharmacopeia of medicines to ... But while questions persist about whether such natural remedies are ... examining the phenomenon from a unique perspective, and trying to ...
Cached Biology News:Gene mutations linked to most cases of rare disorder -- Alternating Hemoplegia of Childhood 2Gene mutations linked to most cases of rare disorder -- Alternating Hemoplegia of Childhood 3Pollution can make citizens - both rich and poor - go green 2Health care savings, naturally 2Health care savings, naturally 3
(Date:9/19/2014)... St. Paul, Minnesota (PRWEB) September 19, 2014 ... representatives from related food industries will gather October ... Meeting at the Rhode Island Convention Center in ... exhibition will feature the work of food scientists, ... development, quality control, and food production management. To ...
(Date:9/19/2014)... Massachusetts , September 19, 2014 ... the 53rd European Society for Paediatric Endocrinology (ESPE) Meeting  ... of science and medical research in the field of ... Merck KGaA, Darmstadt, Germany , today ... Innovation (GGI) for 2014. The awards were announced during ...
(Date:9/18/2014)... Bipartisan passage this week by the U.S. ... development and commercialization of new technologies and promote growth ... SPIE, the international society for optics and photonics ... (RAMI) Act, now moves to the full Senate for ... optimistic that it will win passage there as well ...
(Date:9/18/2014)... LONDON , Sept. 18, 2014 ... near-patient testing, is performed outside a clinical laboratory. ... hence in administrating appropriate treatments and medication. POCT ... and prevalence of lifestyle diseases such as diabetes, ... and user-friendly. POCT devices are standardized to minimize ...
Breaking Biology Technology:Latest Research on Cereal Grain Quality, Health Benefits and Food Production to be Presented During the AACC International Annual Meeting 2Latest Research on Cereal Grain Quality, Health Benefits and Food Production to be Presented During the AACC International Annual Meeting 3EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 2EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 3House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 3POCT Market in China 2014-2018 2
... PRXL ) has appointed Charles A. Stevens as ... Strategic Reimbursement Services, a,unit based in the Washington, ... dedicated to helping PAREXEL,s clients provide solutions to ... they require. His,responsibilities include managing reimbursement service and ...
... WOODLANDS, Texas, Dec. 10 Lexicon,Pharmaceuticals, Inc. (Nasdaq: ... management will participate in the RBC Capital Markets,Healthcare Conference ... at The Westin Times Square Hotel in New York, ... Eastern Time., A live audio webcast of the ...
... Nash Corporation,(Nasdaq: KNSY ) is scheduled to participate ... & Tissue" at the 2007 RBC Capital Markets,Healthcare Conference., ... in the panel,discussion on Thursday, December 13th at 8:00 ... in New York. The conference is by invitation only,however ...
Cached Biology Technology:PAREXEL Appoints Charles A. Stevens as Vice President/General Manager of Health Policy and Strategic Reimbursement and Strengthens Capabilities 2PAREXEL Appoints Charles A. Stevens as Vice President/General Manager of Health Policy and Strategic Reimbursement and Strengthens Capabilities 3PAREXEL Appoints Charles A. Stevens as Vice President/General Manager of Health Policy and Strategic Reimbursement and Strengthens Capabilities 4PAREXEL Appoints Charles A. Stevens as Vice President/General Manager of Health Policy and Strategic Reimbursement and Strengthens Capabilities 5Lexicon Pharmaceuticals to Present at RBC Capital Markets Healthcare Conference 2
... Jouan MSC series of Class II ... conditions and certification to the world's ... ensures that the cabinets cannot be ... Natural lighting, low noise and arm ...
... Fluoroskan Ascent is a dedicated ... for all kinds of assays ... and for clinical applications. Cell ... are all important application areas. ...
... A sleek design loaded with class-leading features, the ... that your work is safe and consistent every time ... the new 1400 Series reduces power consumption by as ... of dollars over the life of the cabinet. ...
... The Magnetic Stand-96 is designed for paramagnetic ... and 0.2 ml PCR plates with no ... polyacryl base in a standard SBS 96-well ... strong permanent magnets guarantees easy and fast ...
Biology Products: