Navigation Links
Niacin, the fountain of youth
Date:9/30/2013

ns, Ristow demonstrated that the health-enhancing effect of endurance sports is mediated via an increased formation of reactive oxygen species and that antioxidants abolish this effect. Based on the present study, he concludes that niacin brings about a similar metabolic condition to exercise. "Niacin tricks the body into believing that it is exercising even when this is not the case," says Ristow. Such compounds are known as "exercise mimetics".

The researchers conducted their experiments on the model organism Caenorhabditis elegans. This worm, which is merely one millimetre in length, can be easily maintained and has a lifespan of only a month, making it the ideal model organism for ageing research.

Also relevant for humans

The results of the study may also be of relevance for humans, says Ristow. After all, the metabolic pathway initiated by niacin is very similar in roundworms and higher organisms. Whether niacin has similar effects on the life expectancy of mice is the subject of Ristow's current research. Previous studies also suggest a health-enhancing effect of niacin in humans with elevated blood cholesterol levels.

Niacin and nicotinamide have been approved as dietary supplements for decades. Ristow could easily envisage the substances being used broadly for therapeutic purposes in the future. A whole series of foods naturally contain niacin, including meat, liver, fish, peanuts, mushrooms, rice and wheat bran. Whether nutritional uptake is sufficient for a health-enhancing or lifespan-extending effect, however, remains to be demonstrated, says Ristow.


'/>"/>

Contact: Michael Ristow
michael-ristow@ethz.ch
41-446-557-446
ETH Zurich
Source:Eurekalert

Page: 1 2

Related biology news :

1. Fountain of youth technique rejuvenates aging stem cells
2. Youthful stem cells from bone can heal the heart, Temple scientists report
3. Diet additions may help youth with type 1 diabetes keep producing own insulin
4. Parents say that healthy eating is challenging for youth who play sports
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... 11, 2014 Researchers have pioneered a revolutionary ... new technology, called Virtual Finger, allows scientists to ... neurons and synapses using the flat surface of ... 3D imaging studies orders of magnitude more efficient, ... level across many areas of experimental biology. The ...
(Date:7/11/2014)... cannabinoid receptor type 1 can inhibit voltage-gated ... reduce neurotransmitter release. However, some scholars demonstrated ... extracellular Ca2+ influx and increase neurotransmitter release. ... Hospital Affiliated to Tongji Medical College, Huazhong ... whole cell voltage-clamp and calcium imaging in ...
(Date:7/10/2014)... SPRINGS, Colo. , June 27, 2014 /PRNewswire/ ... that the National Institute of Standards and Technology ... 10 of its academic research and forensic science ... (FSSB).  The Board is an element of the ... AAFS members are among the first appointments made ...
Breaking Biology News(10 mins):Virtual finger enables scientists to navigate and analyze complex 3D images 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 3
... the first edition published 25 years ago, Molecular Biology of ... as the most influential cell biology textbook of its time ... million people around the world. The new ... authority, accuracy, and clarity. The book has been completely revised ...
... -- Detecting pollution, like catching criminals, requires evidence and ... oceans, having enough detectors is easier said than done. ... and air policy specialists at Arizona State University may ... Protection Agency, they have developed a new way to ...
... need look no farther than the broom closet to solve ... all stages of their lives, with an average of 96 ... younger fleas. In fact, the results were so ... insect specialist, repeated the experiments several times to be sure ...
Cached Biology News:Molecular Biology of the Cell celebrates 25 years of publication 2ASU researchers use NASA satellites to improve pollution modeling 2Cat fleas' journey into the vacuum is a 'one-way trip' 2Cat fleas' journey into the vacuum is a 'one-way trip' 3
(Date:7/10/2014)... , July 10, 2014 Research and ... of the "International Photonic Integrated Circuit (Monolithic ... to 2019" report to their offering. ... The concept of photonic integration traces its roots ... The promise of photonic integration went unexplored and ...
(Date:7/10/2014)... in the fight against terrorism with the creation of ... with the use of light and special glass fibres. ... B: Chemical , the researchers describe a novel optical ... low as 6.3 ppm (parts per million). It requires ... "Traditionally explosives detection has involved looking for metals that ...
(Date:7/10/2014)... psychiatric disorders has been extremely challenging because there are ... insufficient to cause disease. Now investigators reporting in the ... Cell Stem Cell describe a strategy that may ... other risk factors or environmental exposures to affect the ... genetic variant that may predispose individuals to schizophrenia. ...
(Date:7/10/2014)... spiders can sit upside down forever. Nanophysics makes sure of ... an article just published in Physical Review E . ... and spiders that seem to be able to sit still ... for many years. We will soon be able to buy ... gecko,s foot. But the fact is, sooner or later the ...
Breaking Biology Technology:International Photonic Integrated Circuit (Monolithic Integration, Hybrid Integration, Module Integration) Market - Forecasts to 2019 2Detecting trace amounts of explosives with light 2New strategy could uncover genes at the root of psychiatric illnesses 2Even geckos can lose their grip 2
... provides the Company and investor an option to sell or ... purchase additional $67.5 million in securities, SEATTLE, April ... CTIC ; MTA) today announced that it has,entered into agreements ... Series E Convertible Preferred Stock (the "Preferred,Stock"), 13.5% Convertible Senior ...
... 29 Onyx,Pharmaceuticals, Inc. (Nasdaq: ONXX ) today ... discuss first quarter 2008 financial,results and provide a general ... Eastern Time (2:00 p.m. Pacific Time). Financial results for ... earlier that day., Interested parties may access a ...
... SOUTH SAN FRANCISCO, Calif., April 29 ,Anesiva, Inc. ... exclusive Zingo(TM),marketing and distribution agreement, with Green Vision ... powder intradermal injection system is approved in the ... IV insertions or blood,draws in children three to ...
Cached Biology Technology:Cell Therapeutics, Inc. Sells $64.5 million Units Consisting of Preferred Stock, New 2014 Convertible Senior Notes and Warrants to a Single Institutional Investor 2Cell Therapeutics, Inc. Sells $64.5 million Units Consisting of Preferred Stock, New 2014 Convertible Senior Notes and Warrants to a Single Institutional Investor 3Anesiva Announces New Zingo Marketing and Distribution Agreement 2Anesiva Announces New Zingo Marketing and Distribution Agreement 3
...
...
... cabinets Heraeus HERAsafe KS convince with an optimum ... new frameless slanted window does not obscure the ... window design makes it easy to work in ... a height of more than 250 mm ensures ...
... Thermo has recently launched a custom ... RNA (siRNA). Thermos siRNA molecules are: ... with 2 DNA bases overhang at ... Delivered fully deprotected and ready-to-use. ...
Biology Products: