Navigation Links
News tips from the journal mBio®
Date:8/31/2011

. The organism manipulates macrophages to create the PV as well as optimal conditions for growth.

Circumstantial evidence has suggested that C. burnetii is able to exert this control using proteins that are delivered via a mechanism called a Dot/Icm type IVB secretion system (T4BSS) which is critical for successful parasitism of macrophages by the organism.

Using new genetic tools, researchers from the National Institute of Allergy and Infectious Diseases and the University of Arkansas for Medical Science have finally verified that Dot/Icm function is in fact essential for productive infection of human macrophages by C. burnetii.

http://mbio.asm.org/content/2/4/e00175-11

________________________________________

Protein Necessary for Bacteria to Produce Ulcers

When it comes to the ability of the bacterium Helicobacter pylori to effectively colonize the stomach and eventually cause ulcers it all comes down to a single protein.

H. pylori strains infect half of all humans worldwide and contribute to the development of peptic ulcers and gastric cancer. They cannot survive the harsh acidic environment inside stomach cavity and must therefore use their flagella to actively swim to and colonize the protective mucus and lining of the stomach. Researchers have discovered a novel protein, called ChePep, that the bacterium requires to swim properly.

Although H. pylori lacking ChePep have normal looking flagella and are mobile, when they swim they have a slight defect that can cause them to go backwards. If they cannot swim away from the acid and into the protective lining of the stomach, they die.

While ChePep is not unique to H. pylori it is unique to the class Epsilonproteobacteria, which includes the foodborne pathogen Campylobacter jejuni and the deep sea hydrothermal vent inhabitant Caminibacter mediatlanticus.

'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Lack of free play among children is causing harm, say experts in American Journal of Play
2. Journal of Vascular and Interventional Radiology increases impact, offers new initiatives
3. Announcing Cell Reports -- a new open-access journal from Cell Press
4. Fadang photo makes the cover of major botanical journal
5. Pensoft Publishers launch a new mycological open-access journal
6. AGU journal highlights -- July 15, 2011
7. Groundbreaking new journal on the applications of digital games to human health
8. Wiley-Blackwell announces continued growth in impact factor journals
9. Editor-in-chief of leading robotics journal responds to Obamas robotics initiative
10. New 2010 impact factors -- Cell Press journals deliver top class performances
11. AGU journal highlights -- June 23, 2011
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/12/2015)... March 12, 2015 IriTech, a leading iris ... of the Texas Instruments Design Network, announced today that ... demonstrated its IriShield USB MK2120U device during a launching ... pension distribution. The iris scanner is ... marketed in India through its ...
(Date:3/12/2015)... Calif. , March 12, 2015 WHEN:Tuesday, ... Complimentary Registration here: http://bit.ly/1G7Os0L . SPEAKERS: , ... Aravind SeshagiriPhoto - http://photos.prnewswire.com/prnh/20150311/181111 ... order to compete in several different markets and ... is currently witnessing an uptrend. ...
(Date:3/10/2015)... NEW YORK , March 10, 2015  Continuing ... and the Unexpected, Hammacher Schlemmer introduces The Eye ... user,s identity before granting access to secure websites or ... trusted to verify travelers at international borders, the device ... 240 distinctive pattern points of the iris, converting them ...
Breaking Biology News(10 mins):Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 2Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 3Biometrics Key to Future Growth in Healthcare, Retail and Financial Markets 2Biometrics Key to Future Growth in Healthcare, Retail and Financial Markets 3Hammacher Schlemmer Introduces The Eye Scanning Password Authenticator 2
... PITTSBURGHResearchers at Carnegie Mellon University and Stanford University are ... game play to create RNA designs that are then tested ... W.M. Keck Foundation. , Among the additions already implemented is ... RNA molecules that change shape in the presence of other ...
... Bethesda, MD March 15, 2012 -- A new ... journal Genetics shows why the development ... so difficult. In the report, an Australian scientist explains how ... from a single human immunodeficiency virus can evolve fast enough ...
... one generation of tree-killing offspring annually, some populations of ... dramatically increasing the potential for the bugs to kill ... researchers have found. Because of the extra annual ... times as many beetles attacking trees in any given ...
Cached Biology News:Keck award enables Carnegie Mellon and Stanford to dramatically expand crowdsourced RNA design 2Computer simulations help explain why HIV cure remains elusive 2Surprising pine beetle breeding habits help explain increasing tree damage, says CU study 2
(Date:3/27/2015)... , 27. März 2015  Peter ... in Biomedical Science für seine bahnbrechende Arbeit ... zwischen Zellkompartimenten transportiert werden, sowie für die ... zur Reaktion auf Stress nutzen, der mit ... Walter ist Professor für Biochemie an der ...
(Date:3/27/2015)... -- WuXi PharmaTech (Cayman) Inc. (NYSE: WX ... platform company serving the global pharmaceutical, biotechnology, and ... New Drug (IND) application for WuXi MedImmune,s novel ... accepted for review by the China Food and ... 2012, MedImmune, the global biologics research and development ...
(Date:3/26/2015)... TORONTO , March 26, 2015 /PRNewswire/ - SQI ... SQIDF) announced that after dealing with certain matters, including ... of shareholders held on March 26, 2015 (the "Meeting") ... until April 8, 2015 at 11:00 a.m. ( ... Meeting has been changed from that previous disclosed. The ...
(Date:3/26/2015)... , March 26, 2015 ... a global clinical research organization , ... a definitive agreement to acquire all of ... ("QSI"), a leading provider of specialized pharmacovigilance ... to the collection, detection, assessment, monitoring, and ...
Breaking Biology Technology:Deutschstämmiger Zellbiologe Peter Walter gewinnt den Vilcek Prize in Biomedical Science 2015 2Deutschstämmiger Zellbiologe Peter Walter gewinnt den Vilcek Prize in Biomedical Science 2015 3Deutschstämmiger Zellbiologe Peter Walter gewinnt den Vilcek Prize in Biomedical Science 2015 4Investigational New Drug Application for WuXi MedImmune's Monoclonal Antibody Accepted for Review by CFDA 2Investigational New Drug Application for WuXi MedImmune's Monoclonal Antibody Accepted for Review by CFDA 3SQI Diagnostics Inc. Announces Adjournment of Meeting 2PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 2PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 3PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 4
... & Development Team, CLINTON, N.J., June ... critical care biotherapeutics company, announced that Michael,Cooreman, ... of Translational,Medicine, reporting to Ralf Rosskamp, M.D., ... Ikaria., As Vice President of Translational ...
... Generation Biofuels,Holdings, Inc. (AMEX: GNB ), a renewable ... (AMEX) in mid-April, will join the Russell,Microcap Index when ... June 27th, after the market closes, according to a,preliminary ... Membership in the Russell Microcap Index, which remains ...
... ... Reporting, MOUNTAIN VIEW, ... provider of software, strategic,consulting, and regulatory services for optimizing clinical drug,development, ... of bundled software coupled with a rapid deployment,service provided at a ...
Cached Biology Technology:Ikaria Introduces Dr. Michael Cooreman as Vice President of Translational Medicine 2Ikaria Introduces Dr. Michael Cooreman as Vice President of Translational Medicine 3New Generation Biofuels Set to Join Russell Microcap Index 2New Generation Biofuels Set to Join Russell Microcap Index 3Pharsight Launches PK Accelerator(TM) 2Pharsight Launches PK Accelerator(TM) 3Pharsight Launches PK Accelerator(TM) 4Pharsight Launches PK Accelerator(TM) 5
...
... Error-free cloning of BAC (100+kb), fosmid (40kb), ... insert stability than any othe BAC vector. ... high yields and easy recombinant DNA purification. ... transcription-free (pSMART VC) vectors for the highest ...
... PCRx Enhancer System is used ... to optimize PCR of problematic ... PCRX Enhancer Solution with 10X ... primer specificity broader magnesium concentration ...
6-carboxy-2',4,4',5',7,7'-hexachlorofluorescein, succinimidyl ester (6-HEX, SE) *single isomer*...
Biology Products: