Navigation Links
Newly identified proteins make promising targets for blocking graft-vs.-host disease
Date:10/31/2013

The researchers validated their findings in laboratory studies to look at T-cell functions in cell cultures and in mice. Importantly, when they blocked the proteins, it impacted the T-cell function and reduced graft-vs.-host disease in mice.

"We know a lot of proteins play a role in T-cell responses. We're adding more to the armory. Our initial validations in mice are preliminary, but a promising start," says senior study author Pavan Reddy, M.D., professor of hematology/oncology at the U-M Medical School.

This research is still in its early stages. No compounds currently are known to target Wapal or Synj1. Additional research is needed.


'/>"/>

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert  

Page: 1 2

Related biology news :

1. UF: Newly discovered tiger shark migration pattern might explain attacks near Hawaii
2. Newly discovered ocean plume could be major source of iron
3. Newly discovered switch plays dual role in memory formation
4. Newly discovered bacterial partnership changes ocean chemistry
5. ACLS Online Renewal Course from United Medical Education Now Features Newly-Updated Course Materials
6. Newly identified bone marrow stem cells reveal markers for ALS
7. Newly developed medium may be useful for human health, biofuel production, more
8. A newly discovered hormone makes ovaries grow
9. Newly described type of immune cell and T cells share similar path to maturity
10. FRAX newly released as version 3.8 -- Over 5 million online calculations since June 2011
11. Marriage can threaten health: Study finds satisfied newlyweds more likely to gain weight
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Newly identified proteins make promising targets for blocking graft-vs.-host disease
(Date:12/10/2014)... You,ve been here before: you desperately need to sign into ... key or the answer to your secret question. What,s your ... Today, Hoyos Labs , a digital infrastructure security ... an end to the frustration that comes with usernames, passwords ... a user,s smartphone to acquire his or her biometrics to ...
(Date:12/10/2014)... 08, 2014 Research and Markets ... the "Biometrics Market in Japan 2014-2018" ... http://photos.prnewswire.com/prnh/20130307/600769 The integration of ... rural banking and upgradation of the driver,s license ... the market. Besides the aforementioned projects, biometrics is ...
(Date:12/4/2014)... GARDENS, Fla. , Dec. 3, 2014 /PRNewswire/ ... solutions, today announced that its DigitalPersona ® ... fingerprint readers have been deployed throughout First Bank ... , South Carolina and ... in Southern Pines, North Carolina ...
Breaking Biology News(10 mins):The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2First Bank Partners with Crossmatch to Increase Log In Security 2First Bank Partners with Crossmatch to Increase Log In Security 3
... survival strategy of the parasite that causes sleeping sickness could ... found that the parasite, which can transform itself into either ... these. One of these types ensures infection in the bloodstream ... by the tsetse fly and spread to another person or ...
... is available in German . It would ... would have similar genetic blueprints. However, scientists from the Max ... with an international research team have now decoded, for the ... ( Arabidopsis lyrata ), a close relative of the thale ...
... release is available in Spanish . ... Agriculture (USDA) scientists and colleagues can improve polymerase chain ... PCR-based tests are prized tools for diagnosing plant ... among other economic harm. But the test,s ability to ...
Cached Biology News:Evolution can cause a rapid reduction in genome size 2Evolution can cause a rapid reduction in genome size 3New technique improves sensitivity of PCR pathogen detection 2
(Date:12/19/2014)... 18, 2014 Relmada Therapeutics, Inc. (OTCQB: RLMD), ... of chronic pain, announced the results of its annual ... was a transformational year in Relmada,s history and it ... company," said Sergio Traversa , chief executive officer ... on key financial, human resource and clinical development objectives ...
(Date:12/17/2014)... December 17, 2014 Based on ... overall surgical imaging market is dominated by four ... surgical imaging market. These players include GE Healthcare ... Imaging (Germany). , Full Report Copy at ... GE Healthcare can be attributed to its strong ...
(Date:12/17/2014)... Achim Noack has been named global vice president ... position, Noack will assist Jerry Stoller, CEO and president ... and supervise global marketing management and implementation of new ... and experience in the crop protection industry,” says Jerry ... thinking will be a great asset for Stoller Group, ...
(Date:12/17/2014)... Long Beach, CA (PRWEB) December 17, 2014 ... Technology, Inc. to provide a larger packaged waste water ... district in King Abdullah Economic City (KAEC). Two years ... for EMAAR’s Jeddah Gate Development, serving two residential towers ... plant capacity is over a quarter million gallons per ...
Breaking Biology Technology:Relmada Therapeutics Announces Results of Annual Shareholders Meeting 2Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 2Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 3Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 4Achim Noack Joins Stoller Group as Global Vice President of Marketing and Administration 2
... Development of Nano-Materials for Angiogenesis Applications , ... OmegaGenesis announced today that they have entered into a ... nano-materials used for Angiogenesis applications. , , ... variety of medical applications ranging from tissue reactivation and healing ...
... 3 Combination Rule Trial for NDA Submission , ... N.J., Dec. 15 QRxPharma Limited (ASX: QRX and ... the development and commercialization of therapies for pain and ... a comparative study to evaluate the efficacy and safety ...
... N.Y., Dec. 15 Allscripts,announced today that ... multispecialty group practice, has selected Allscripts,Practice Management ... for their 190 physicians. , ... ) , ...
Cached Biology Technology:OmegaGenesis Announces Angiogenesis Application Collaboration 2OmegaGenesis Announces Angiogenesis Application Collaboration 3QRxPharma Initiates Comparative Study for MoxDuoIR(TM) Dual-Opioid(TM) Pain Therapy 2QRxPharma Initiates Comparative Study for MoxDuoIR(TM) Dual-Opioid(TM) Pain Therapy 3Community Care Physicians Selects Allscripts Practice Management System for 190 Physicians in New York Capitol Region 2Community Care Physicians Selects Allscripts Practice Management System for 190 Physicians in New York Capitol Region 3Community Care Physicians Selects Allscripts Practice Management System for 190 Physicians in New York Capitol Region 4Community Care Physicians Selects Allscripts Practice Management System for 190 Physicians in New York Capitol Region 5
Anti-DDDDK-Tag (Enterokinase Cleavage Site), Agarose Conjugate Research Focus: tag Storage: 4C Shipping Temperature: 4C...
Goat polyclonal to XAGE1 ( Abpromise for all tested applications). Antigen: Synthetic peptide: CGFGFRRQGEDNT, corresponding to C terminal amino acids 149-160 of Human XAGE1 Entrez Gene ID: 9...
Sheep polyclonal to Staphylococcus DNase ( Abpromise for all tested applications). Antigen: Full length native protein (purified)....
Mouse monoclonal [MN-8C4] to zona radiata ( Abpromise for all tested applications). Antigen: Purified eggshell proteins (zona radiata proteins and small amounts of zona pellucida proteins) from ...
Biology Products: